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Fc (IgG1) Protein

Fc Protein (IgG1)
Catalog No. Product Name Size List Price (US$) Quantity
BP4111 Recombinant Mouse Fc Protein (IgG1) 1 mg 1800.00
Description

Background

The Fc (Fragment, crystallizable) region, located in the base of the Y-shape antibody and composed of two heavy chains with two or three constant domains depending on the class of the antibody, binds to a specific class of Fc receptors and other immune molecules, such as complement proteins, to induce an appropriate immune response for a given antigen. The Fc region bears two highly conserved N-glycosylation sites, one on each heavy chain. The N-glycans attached to this site are predominantly core-fucosylated diantennary structures of the complex type. In addition, small amounts of these N-glycans also bear bisecting GlcNAc and α-2,6-linked sialic acid residues.

BP4111: Recombinant Mouse Fc protein (IgG1)

The recombinant mouse IgG1 Fc protein was produced in HEK 293 cells and purified by protein A.
Molecular weight: about 55 kDa.
Purity: >95% by SDS-PAGE under reducing conditions
Endotoxin Level: Less than 1 EU/ug of protein as determined by LAL method.
Formulation: 0.2 μM filtered solution of 200 mM HEPES, 100 mM NaCl, 50 mM NaOAc, pH 7.

Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
1 month from date of receipt, 2 to 8°C as supplied.
3 months from date of receipt, -20°C to -70°C as supplied.

Other Recombinant IgG Fc Proteins:
Recombinant Human Fc Protein (IgG1)
Recombinant Human Fc Protein (IgG2)
Recombinant Human Fc Protein (IgG4)

Recombinant IgG Reference Antibodies:
Recombinant Human IgG1 Reference Antibody
Recombinant Human IgG2 Reference Antibody
Recombinant Human IgG4-S228P Reference Antibody
Recombinant Mouse IgG1 Reference Antibody
Recombinant Mouse IgG2a Reference Antibody
Recombinant Mouse IgG2b Reference Antibody

Fc ELISA Kits and Reagents:
Human Fc ELISA Kit
Mouse Fc ELISA Kit
Human Fc ELISA Reagent Kit
Mouse Fc ELISA Reagent Kit

Protein A, Resin, Columns, and ELISA Kits:
Recombinant Protein A
Protein A Affinity Resin
Pre-packed Protein A Column
Protein A ELISA Kit

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