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Home > Services > Antibody Services
Services for antigen preparation, custom antibody production, antibody purification, antibody modification, characterization/testing antibodies, packaging antibodies, and various antibody applications.
    29 Antibody Services
  • BS046B:
    Gene synthesis of the variable regions of the recombinant IgG antibodies;
    Molecular construction of the recombinant IgG antibodies;
    0.04 Liter transient production of the recombinant IgG antibodies in CHO cells;
    Protein A purification.

  • BS079B:
    Gene synthesis of the variable regions of the recombinant scFv-Fc antibodies;
    Molecular construction of the recombinant scFv-Fc antibodies;
    0.04 Liter transient production of the recombinant scFv-Fc antibodies in CHO cells;
    Protein A purification.

  • The most comprehensive rat monoclonal antibody development services: custom production of rat monoclonal antibodies against non-modified, phospho-specific, methylation-specific, and acetylation-specific peptides and proteins; monoclonal antibodies for ELISA, Western blot, IP, IF, ICC, and IHC applications.

    The highest quality standard in the field of rat monoclonal antibody development services: guaranteed ELISA > 1:40,000.

    Choice for licensing antibodies to save your cost and even make money.

    Fast turnaround: 24 weeks once the antigen is available.

  • The most comprehensive hybridoma-based mouse monoclonal antibody production services: custom production of monoclonal antibodies against non-modified, phospho-specific, methylation-specific, and acetylation-specific peptides and proteins as well as small molecular compounds; for ELISA, Western blot, IHC, and flow cytometry applications.

    The lowest custom mouse monoclonal antibody production price: $6000.

    Fast turnaround: 24 weeks once the antigen is available.

  • Custom Ilama and alpaca monoclonal antibody development (VHH, sdAb or nanobody) by Ilama or alpaca immunization and phage display screening.

    Production of camel, Ilama or alpaca VHH in E.coli or VHH-Fc in HEK 293 cells.

    Fast turnaround: 4-6 months once the antigen is available.

  • The most comprehensive murine hybridoma generation for therapeutic antibody services:

    Genetic background: white, black, immunodeficiency, knock-out, and humanized mice; rat; hamster;

    Antigens: proteins, peptides, DNA, cells expressing certain proteins.

    All are done in US.

  • The most comprehensive rabbit polyclonal antibody production services with the gold standard of rabbit immunization service (1 immunization and 4 boosts): custom production of rabbit polyclonal antibodies (pAb) against non-modified, phospho-specific, methylation-specific, and acetylation-specific peptides and proteins; rabbit polyclonal antibodies for ELISA, Western blot, IP, IF, ICC, and IHC applications.

    The highest quality standard in the field of rabbit polyclonal antibody production services: guaranteed ELISA > 1:64,000 (antisera) and > 1: 128,000 (purified antibodies).

    Fast turnaround: 10 weeks once the antigen is available.

  • The most comprehensive rabbit monoclonal antibody production services: custom production of rabbit monoclonal antibodies against non-modified, phospho-specific, methylation-specific, and acetylation-specific peptides and proteins; rabbit monoclonal antibodies for ELISA, Western blot, IP, IF, ICC, and IHC applications. Syd Labs team has successfully developed a large number of high specificity and high affinity rabbit monoclonal antibodies against a wide range of difficult targets such as small molecules, antibody idiotype, and antigens non-immunogenic in murine, camel or Ilama.

    Fast turnaround: 18 weeks once the antigen is available.

  • Single B cell antibody cloning and sequencing has become popular for antibody discovery, especially for those difficult to obtain.  After antigen specific single B cell sorting, the single B cells can be directly used for antibody seqencing or cultured for 2 weeks before antibody sequencing. Single B cell sequencing by Sanger DNA sequencing or next generation sequencing (NGS) has been successfully applied to single B cell antibody technologies.

  • 100000 cells per hybridoma clone are sufficient for cloning and sequencing the monoclonal antibody variable regions (both VH and VL) and full length. Welcome to challenge us with smaller number of clonal B cells or non-viable cells for hybridoma rescue.

    - Reliable results. With optimized workflow and PCR primers, we have successfully cloned and sequenced >3000 antibodies from various species in the past 10 years. Syd Labs has become a reliable CRO supplier of antibody sequencing to biotech and biopharma companies, government agencies including FDA and NIH, and universities. Clients' samples of hybridoma cell lines or clonal B cells just need to meet 2 requirements: functional antibodies are secreted by the cells; enough RNA remains.
    - Save time. One may learn how to clone and sequence antibody genes by studying hybridoma antibody cloning and antibody sequencing protocols that we collected from public literature. Generally speaking, it is more difficult to clone antibody genes from rodents than other species; among isotypes, it is the easiest to clone IgG genes, especially IgG1. A couple of companies sell such kits and PCR primers. However, it takes time to become a highly efficient and experienced professional for so many lab skills and bioinformatics analysis involved in such projects. In addition, there are some samples invaluable but difficult to work. Some service suppliers spend months but could not solve the problem, just wasting clients' samples and time.
    - Save money. Since we process samples from multiple clients in the same time, our cost is lower than clients'. Our low cost molecular biology reagents further save clients' cost.

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