Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
|---|
In vivo grade recombinant natural and engineered rabbit IgG Fc proteins (rIgG Fc), and recombinant rabbit IgG isotype control antibody and mutants are available. Biotinylated rIgG Fc, and rIgG Fc with Avi-, His-, and Flag-tags are also available.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
In vivo grade recombinant natural and engineered rabbit IgG Fc proteins (rIgG Fc), and recombinant rabbit IgG isotype control antibody and mutants are available. Biotinylated rIgG Fc, and rIgG Fc with Avi-, His-, and DYKDDDDK-tags are also available. Please contact us to ask for a quote for the engineered rabbit IgG Fc proteins, biotinylated rIgG Fc, and rIgG Fc with Avi-, His-, and Flag-tags. The recombinant rabbit IgG Fc protein and mutants can be used as the isotype control of the rIgG antibodies and the rIgG Fc fusion proteins in various in vitro and in vivo experiments.
The in vivo grade recombinant rabbit IgG Fc protein (rIgG Fc, Cys 105 - Lys 323 of the constant region of the IgG heavy chain, Accession # P01870-1) was produced in mammalian cells and purified by protein A. The rIgG Fc protein includes the CH2 (114-213) and CH3 (222-323) domains of the heavy chain constant region as well as the hinge region (105-113) before the CH2 domain.
Molecular weight: Predicted 24.8 kDa. Due to glycosylation, the recombinant rabbit IgG Fc protein migrates to 28-32 kDa based on the Bis-Tris PAGE result.
Purity: >95% by SDS-PAGE under reducing conditions
Endotoxin Level: Less than 1 EU/mg of protein as determined by LAL method.
Formulation: 0.2 μM filtered solution of 1x PBS.
Shipping: The in vivo grade recombinant rabbit IgG Fc protein is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
1 month from date of receipt, 2 to 8°C as supplied.
3 months from date of receipt, -20°C to -70°C as supplied.
Macrophage-derived extracellular vesicles transfer mitochondria to adipocytes and promote adipocyte-myofibroblast transition in epidural fibrosis.
Hua, F., et al. NPJ Regen Med. 2024 Dec 30;9(1):43. doi: 10.1038/s41536-024-00388-6. PMID: 39738050
Briefly, the embedded tissues were cut into 4 ?m thick sections and incubated with anti-?-SMA and anti-PLIN1 at 4°C for 24?h. Then, the slides were incubated with goat anti-rabbit IgG and goat anti-mouse IgG for 2?h at 27°C and then observed under the fluorescence microscope. ...Following this, the slides were incubated with goat anti-rabbit IgG and goat anti-rat IgG for 2?h at 27°C and then observed under a fluorescence microscope. ...Epidural fibrosis post laminectomy is the leading cause of failed back surgery syndrome. ...Little is known about the role and mechanisms of adipose tissues in epidural fibrosis. ...Mechanistically, large extracellular vesicles (EVs) from M2-type macrophages transfer mitochondria into adipocytes and promote AMT by activating the TGF-? and PAI-1 pathways. Blocking the PAI-1 pathway significantly attenuated the transition of adipocytes into myofibroblasts.
Tags: activity of Rabbit IgG Fc Protein; Rabbit IgG Fc Protein
The MuSK-BMP pathway maintains myofiber size in slow muscle through regulation of Akt-mTOR signaling.
Jaime, D., et al. Skelet Muscle. 2024 Jan;14(1):1. doi: 10.1186/s13395-023-00329-9. PMID: 38172960
For muscle fiber sizing experiments, sections of WT and ?Ig3-MuSK TA and soleus muscles were rehydrated and blocked in 20% goat serum then incubated with anti-dystrophin diluted to 1:400 overnight and detected with goat anti-rabbit IgG Alexa Fluor 488 secondary antibodies. ...Sections were fixed with 1% PFA, washed, and blocked with 2% BSA and 5% goat serum in PBS. ...Images were acquired on a Nikon Ti2-E inverted microscope equipped with a Photometrics Prime 95B sCMOS camera for fluorescence imaging and a 16-megapixel Nikon DS-Ri2 color camera for imaging histology slides. ...For visualization of NMJs in whole mount preparations, muscles were collected and pinned at resting length for removal of connective tissue, fixed in 4% PFA for 20 min, fileted into bundles, washed with PBS 3?×?10 min, and labeled with tetramethylrhodamine-conjugated ?-bungarotoxin for 15 min at room temperature. ...MuSK is expressed at all neuromuscular junctions and is also present extrasynaptically in the mouse soleus, whose predominantly oxidative fiber composition is akin to that of human muscle.
Tags: Rabbit IgG Fc Protein for mouse tumor model; function of Rabbit IgG Fc Protein
For more references about Rabbit IgG Fc Protein please contact our scientific support team with message@sydlabs.com.
Other Recombinant IgG Fc Proteins:
In vivo Grade Recombinant Human IgG1 Fc Protein (hIgG1)
In vivo Grade Recombinant Human IgG2 Fc Protein (hIgG2)
In vivo Grade Recombinant Human IgG4 Fc Protein (hIgG4)
In vivo Grade Recombinant Mouse IgG1 Fc Protein (mIgG1)
In vivo Grade Recombinant Mouse IgG2a Fc Protein (mIgG2a)
In vivo Grade Recombinant Mouse IgG2b Fc Protein (mIgG2b)
In vivo Grade Recombinant Mouse IgG2c Fc Protein (mIgG2c)
In vivo Grade Recombinant Mouse IgG3 Fc Protein (mIgG3)
In vivo Grade Recombinant Rat IgG2a Fc Protein (rtIgG2a)
In vivo Grade Recombinant Rat IgG2b Fc Protein (rtIgG2b)
In vivo Grade Recombinant Llama IgG2b Fc Protein (lIgG2b)
In vivo Grade Recombinant Rabbit IgG Fc Protein (rIgG)
Recombinant IgG Reference Antibodies:
In vivo Grade Recombinant Human IgG1 Isotype Control Antibody and Mutants
In vivo Grade Recombinant Human IgG2 Isotype Control Antibody
In vivo Grade Recombinant Human IgG3 Isotype Control Antibody
In vivo Grade Recombinant Human IgG4-S228P Isotype Control Antibody and Mutants
In vivo Grade Recombinant Mouse IgG1 Isotype Control Antibody and Mutants
In vivo Grade Recombinant Mouse IgG2a Isotype Control Antibody and Mutants
In vivo Grade Recombinant Mouse IgG2b Isotype Control Antibody and Mutants
In vivo Grade Recombinant Mouse IgG2c Isotype Control Antibody and Mutants
In vivo Grade Recombinant Mouse IgG3 Isotype Control Antibody
In vivo Grade Recombinant Rat IgG1 Isotype Control Antibody
In vivo Grade Recombinant Rat IgG2a Isotype Control Antibody
In vivo Grade Recombinant Rat IgG2b Isotype Control Antibody
In vivo Grade Recombinant Rat IgG2c Isotype Control Antibody
Fc ELISA Kits and Reagents:
Human Fc ELISA Kit
Mouse Fc ELISA Kit
Human Fc ELISA Reagent Kit
Mouse Fc ELISA Reagent Kit
Protein A, Resin, Columns, and ELISA Kits:
Recombinant Protein A
Protein A Affinity Resin
Pre-packed Protein A Column
Protein A ELISA Kit
Copyright © 2009-2025 sydlabs.com. All rights reserved.
Use of this website means that you have read, understood, and accepted the Syd Labs Privacy Policy and Terms & Conditions.
Friend Link: Ushelf