PA007156.m2c: In Vivo Grade Recombinant Anti-mouse CD25 Mouse IgG2c Kappa Monoclonal Antibody
The in vivo grade recombinant anti-mouse CD25 mouse IgG2c monoclonal antibody was produced in CHO cells.
Applications: immunoprecipitation (IP), immunohistochemistry (IHC), Flow Cytometry (FC), and various functional assays, such as in vivo depletion of CD25+CD4+ Treg cells, in vitro blocking of IL-2 binding to low- and high-affinity receptors, and growth inhibition of IL-2-dependent T-cell lines.
Endotoxin Level: Less than 1 EU/mg of protein as determined by LAL method.PA007156.m2caf: In Vivo Grade Recombinant Afucosylated Anti-mouse CD25 Mouse IgG2c Kappa Monoclonal Antibody
The in vivo grade recombinant afucosylated anti-mouse CD25 mouse IgG2c monoclonal antibody was produced in engineered CHO cells which produce afucosylated antibodies.
Applications: immunoprecipitation (IP), immunohistochemistry (IHC), Flow Cytometry (FC), and various functional assays, such as in vivo depletion of CD25+CD4+ Treg cells, in vitro blocking of IL-2 binding to low- and high-affinity receptors, and growth inhibition of IL-2-dependent T-cell lines.
Endotoxin Level: Less than 1 EU/mg of protein as determined by LAL method.PA000274.h1: In vivo Grade Recombinant DYKDDDDK-Tag Monoclonal Antibody (M2, Human IgG1)
The in vivo grade recombinant DYKDDDDK-Tag monoclonal antibody (M2, human IgG1 kappa) is a chimeric mouse/human monoclonal antibody produced in mammalian cells. It consists of mouse variable regions and human IgG1 kappa constant regions.
Applications: ELISA, flow cytometry, immunoblotting, immunoprecipitation, immunocytochemistry, immunofluorescence, chromatin immunoprecipitation, electron microscopy, supershift assays, protein purification if conjugated with agarose or magnetic beads, and isotype controls.
Reactivity: Human, Mouse, Rat, Others.
Clone: M2;
Isotype: human IgG1.APIM050182: LGX818 (ENCORAFENIB)
CAS No.: 1269440-17-6.
Purity: >99.5% Pure by Achiral and Chiral HPLCs.
QC: Achiral and Chiral HPLCs, MS, NMR, and Quantitative Elemental analysis Report.
Solubility: Refer to Certificate of Analysis.APIM050149: GDC-0068
CAS No.: 1001264-89-6.
Purity: 99% chem and stereomeric purity (HPLC and Chiral HPLC).
QC: HPLC-MS, 1HNMR, Chiral HPLC, and Quantitative Elemental Analysis.
Solubility: Soluble in DMSO.APIM050150: GDC-0941 (FREE BASE)
CAS No.: 957054-30-7.
Purity: >99% (HPLC at 214 and 254 nm).
QC: LC/MS, 1HNMR, HPLC.
Solubility: Soluble in DMSO.APIM050151: GDC-0973 (COBIMETINIB)
CAS No.: 934660-93-2.
Purity: >99% chem and optical purity (by achiral and chiral HPLCs).
QC: Achiral HPLC, 1H-NMR, Chiral HPLC, and Quantitative Elemental Analysis.
Solubility: Refer to COA.APIM050152: GDC-0980
CAS No.: 1032754-93-0.
Purity: >99% chem and optical purity (HPLC and Chiral HPLC).
QC: HPLC-MS, 1HNMR, Chiral HPLC, and Quantitative Elemental Analysis.
Solubility: In DMSO.APIM050153: GDC-0994 (RAVOXERTINIB, RG7842)
CAS No.: 1453848-26-4.
Purity: >99.5% chem and optical purity.
QC: HPLC-MS, 1H-NMR, Chiral HPLC, and Quantitative Elemental Analysis report.
Solubility: Refer to Certificate.APIM050154: GEFITINIB
CAS No.: 184475-35-2.
Purity: > 99% (HPLC).
QC: 1HNMR, HPLC.
Solubility: Soluble in DMSO.APIM050155: GILTERITINIB (ASP2215)
CAS No.: 1254053-43-4.
Purity: >99.5% (HPLCs at 220 and 254 nm).
QC: HPLC-MS, 1HNMR, and Quantitative Elemental Analysis.
Solubility: Soluble in DMSO.