BP4091: In Vivo Grade Recombinant Human IgG1 Fc protein (hIgG1 Fc)
Source: mammalian cell-derived.
Purity: >95% by SDS-PAGE under reducing conditions
Endotoxin Level: Less than 1 EU/mg of protein as determined by LAL method.Recombinant human IgG1 Fc protein mutants available including hIgG1 Fc C103S; hIgG1 Fc D265A; hIgG1 Fc R214K; hIgG1 Fc R214K/N297A; hIgG1 Fc L234A/L235A; hIgG1 Fc L234F/L235E/P331S; hIgG1 Fc L235A/G237A. Recombinant human IgG1 isotype control antibody and mutants are available. Biotinylated hIgG1 Fc, and hIgG1 Fc with Avi-, His-, and Flag-tags are also available.
APIM050182: LGX818 (ENCORAFENIB)
CAS No.: 1269440-17-6.
Purity: >99.5% Pure by Achiral and Chiral HPLCs.
QC: Achiral and Chiral HPLCs, MS, NMR, and Quantitative Elemental analysis Report.
Solubility: Refer to Certificate of Analysis.APIM050304: IACS-010759 (IACS-10759)
CAS No.: 1570496-34-2.
Purity: 99.8% by HPLC (at 220 and 254 nm).
QC: HPLC-MS, 1H-, 2D- NMRs, and Elemental Analysis Report.
Solubility: Refer to certificate of analysis.APIM050146: FORETINIB
CAS No.: 849217-64-7.
Purity: >99% (HPLC at 214 and 254 nm).
QC: HPLC-MS, 1HNMR and Quantitative Elemental Analysis.
Solubility: In DMSO, alcohols, water with 1 eq. of acid.APIM050147: FRAX486
CAS No.: 1232030-35-1.
Purity: >99% (HPLC at 214 and 254 nm).
QC: HPLC-MS, 1HNMR, and Microanalysis.
Solubility: Soluble in DMSO.APIM050148: GDC-0032 (TASELISIB)
CAS No.: 1282512-48-4.
Purity: >99.5% (HPLC at 214 and 254 nm).
QC: HPLC-MS, 1HNMR, and Quantitative Elemental Analysis.
Solubility: Soluble in DMSO.APIM050149: GDC-0068
CAS No.: 1001264-89-6.
Purity: 99% chem and stereomeric purity (HPLC and Chiral HPLC).
QC: HPLC-MS, 1HNMR, Chiral HPLC, and Quantitative Elemental Analysis.
Solubility: Soluble in DMSO.APIM050150: GDC-0941 (FREE BASE)
CAS No.: 957054-30-7.
Purity: >99% (HPLC at 214 and 254 nm).
QC: LC/MS, 1HNMR, HPLC.
Solubility: Soluble in DMSO.APIM050151: GDC-0973 (COBIMETINIB)
CAS No.: 934660-93-2.
Purity: >99% chem and optical purity (by achiral and chiral HPLCs).
QC: Achiral HPLC, 1H-NMR, Chiral HPLC, and Quantitative Elemental Analysis.
Solubility: Refer to COA.APIM050152: GDC-0980
CAS No.: 1032754-93-0.
Purity: >99% chem and optical purity (HPLC and Chiral HPLC).
QC: HPLC-MS, 1HNMR, Chiral HPLC, and Quantitative Elemental Analysis.
Solubility: In DMSO.