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| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
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Recombinant human PDL1-Fc fusion protein (IgG1), recombinant human PDL1-Flag fusion protein, and recombinant human PD1-Fc fusion protein are also available.
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Source: HEK 293 cell-derived.
The recombinant human PD1-His fusion protein is the human PD1 ECD (amino acids 25-167) fused with a polyhistidine tag at the C-terminus.
Purity: >95% by SDS-PAGE under reducing conditions.
Activity: The recombinant human PD1-his fusion protein binds the recombinant human PDL1 protein at sub-micromolar range.
Formulation: 0.2 μM filtered solution of 30 mM HEPES, 150 mM NaCl, pH 7.
Endotoxin Level: Less than 1 EU/ug of protein as determined by LAL method.
Shipping: The product is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
1 month from date of receipt, 2 to 8°C as supplied.
3 months from date of receipt, -20°C to -70°C as supplied.
Background
Programmed death-1 (PD-1) is a type I transmembrane protein belonging to the CD28/CTLA-4 family of immunoreceptors that mediate signals for regulating immune responses. Members of the CD28/CTLA-4 family both up-regulate (CD28 and ICOS) and downregulate T cell activation (CTLA-4 and PD-1). PD-1 is expressed on activated T cells, B cells, myeloid cells and on a subset of thymocytes. Mouse and human PD-1 share approximately 60% amino acid sequence identity.
Other Recombinant PD1 Protein:
Recombinant Human PD1-Fc Fusion Protein (IgG1)
Recombinant PDL1 Protein:
Recombinant Human PDL1-Fc Fusion Protein (IgG1)
Recombinant Human PDL1-FLAG Fusion Protein
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