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Services for synthesis, detection, identification, separation, purification, production, quantification, and modification of oligonucleotides, RNA, DNA, peptides, and proteins, such as peptide synthesis, gene synthesis, DNA cloning and subcloning, protein expression, custom antibody development, cell line generation, cell and tissue culture, and cell-based assays.
    86 Services
  • BS076: Biotin Conjugation Service

    1. Highly efficient process to conjugate biotin to clients' peptides, proteins or antibodies
    2. The highest possible conjugation yield and stability
    3. Final product can be stored for at least 12 months at -20 C.
    4. Fast turnaround time: 3-5 days

  • BS054: Magnetic Bead Conjugation Service

    Highly efficient process to conjugate magnetic beads to clients' peptides, proteins, and antibodies: the ratio is 20 ug protein or antibody per mg magnetic microbeads in the conjugation reaction; about 6 ug protein or antibody would be conjugated onto the beads at a concentration of 6 ug antibody per mg magnetic beads.

    Fast turnaround time: 3-5 days.

  • - Reliable results. Through development of genome-wide qPCR primers, we have successfully tested over 30,000 genes in qPCR assays. Relative and absolute analysis of gene expression by qPCR is available for all known genes in any organism.
    - Save money. No need to buy real-time PCR instruments or reagents. Our reverse transcription and qPCR reagents are used to save clients' cost.

  • - Reliable results. Through development of genome-wide qPCR primers, we have successfully tested over 30,000 genes in qPCR assays. Relative and absolute analysis of gene expression by qPCR is available for all known genes in any organism.
    - Save money. No need to buy real-time PCR instruments or reagents. Our reverse transcription and qPCR reagents are used to save clients' cost.

  • Custom Ilama and alpaca monoclonal antibody development (VHH, sdAb or nanobody) by Ilama or alpaca immunization and phage display screening.

    Production of camel, Ilama or alpaca VHH in E.coli or VHH-Fc in HEK 293 cells.

    Fast turnaround: 4-6 months once the antigen is available.

  • Our complete custom Adeno-associated Virus (AAV) production services include: 1) AAV plasmid vector construction; 2) AAV packaging; 3) AAV purification by iodixanol or column chromatography; 4) AAV titering by qPCR.

    We have always optimized our AAV production systems, including AAV plasmid vector design and construction and low endotoxin plasmid preparation, host cells for AAV packaging, cell culture medium and AAV packaging process, small and large scale AAV purification process.

    Fast turnaround: 2-3 weeks.

  • The most comprehensive murine hybridoma generation for therapeutic antibody services:

    Genetic background: white, black, immunodeficiency, knock-out, and humanized mice; rat; hamster;

    Antigens: proteins, peptides, DNA, cells expressing certain proteins.

    All are done in US.

  • The most comprehensive rabbit polyclonal antibody production services with the gold standard of rabbit immunization service (1 immunization and 4 boosts): custom production of rabbit polyclonal antibodies (pAb) against non-modified, phospho-specific, methylation-specific, and acetylation-specific peptides and proteins; rabbit polyclonal antibodies for ELISA, Western blot, IP, IF, ICC, and IHC applications.

    The highest quality standard in the field of rabbit polyclonal antibody production services: guaranteed ELISA > 1:64,000 (antisera) and > 1: 128,000 (purified antibodies).

    Fast turnaround: 10 weeks once the antigen is available.

  • The most comprehensive rabbit monoclonal antibody production services: custom production of rabbit monoclonal antibodies against non-modified, phospho-specific, methylation-specific, and acetylation-specific peptides and proteins; rabbit monoclonal antibodies for ELISA, Western blot, IP, IF, ICC, and IHC applications. Syd Labs team has successfully developed a large number of high specificity and high affinity rabbit monoclonal antibodies against a wide range of difficult targets such as small molecules, antibody idiotype, and antigens non-immunogenic in murine, camel or Ilama.

    Fast turnaround: 18 weeks once the antigen is available.

  • Single B cell antibody cloning and sequencing has become popular for antibody discovery, especially for those difficult to obtain.  After antigen specific single B cell sorting, the single B cells can be directly used for antibody seqencing or cultured for 2 weeks before antibody sequencing. Single B cell sequencing by Sanger DNA sequencing or next generation sequencing (NGS) has been successfully applied to single B cell antibody technologies.

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