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Services for synthesis, detection, identification, separation, purification, production, quantification, and modification of oligonucleotides, RNA, DNA, peptides, and proteins, such as peptide synthesis, gene synthesis, DNA cloning and subcloning, protein expression, custom antibody development, cell line generation, cell and tissue culture, and cell-based assays.
    90 Services
  • Custom measurement of endotoxins levels in biological samples such as DNA and protein preparations.
    Maximum sensitivity of 0.01 EU/mL (Endotoxin Units per milliliter).
    Fast turnaround: 3 business days.

  • High quality plasmid DNA for demanding downstream applications: the endotoxin levels in delivered samples are below 0.1 EU per microgram of DNA. Excellent for in vivo and cell culture experiments, transfection and expression.
    Fast turnaround: 5 business days.

  • The standard Western Blot protocol will be used to detect protein expression in solution, cell or tissue samples.

  • - Reliable results. Through development of genome-wide qPCR primers, we have successfully tested over 30,000 genes in qPCR assays. Relative and absolute analysis of gene expression by qPCR is available for all known genes in any organism.
    - Save money. No need to buy real-time PCR instruments or reagents.
    - Save time. Let our technical experts do the experiments for you.

  • - Reliable results. Through development of genome-wide qPCR primers, we have successfully tested over 30,000 genes in qPCR assays. Relative and absolute analysis of gene expression by qPCR is available for all known genes in any organism.
    - Save money. No need to buy real-time PCR instruments or reagents.
    - Save time. Let our technical experts do the experiments for you.

  • - Any gene;
    - Any host cell, including primary cell;
    - Highly efficient and precise.

    Fast turnaround:

    Knock-out cell line generation: 16-19 weeks.
    Knock-in cell line generation: 20-24 weeks.

  • Experienced scientists working on antibody and cell line development services for decades. >90% success rate of stable cell line generation.

    Stable cell lines developed with our proprietary recombinant antibody expression system with multiple selectable markers is very productive in expressing target proteins.

    Fast turnaround:

    Basic service: 7-8 weeks.
    Premium service: 12-14 weeks.
    Pool cells: 6 weeks.

  • Experienced scientists working on antigen and antibody production, antibody engineering, lentivirus, and cell line development services for decades. >90% success rate of stable cell line generation.

    Fast turnaround:

    Antigen (peptide or protein) production: 3-6 weeks.
    Mouse monoclonal antibody production: 20-24 weeks.
    Screening phage or yeast libraries for fully human antibodies: 8-12 weeks.
    Sequencing hybrioma antibody: 1-3 weeks.
    Chimeric antibody production: 3-4 weeks.
    Antibody humanization: 8-10 weeks.
    Construction of CAR cassette, lentivirus packaging and production: 4-5 weeks.
    T-cell activation, transduction, and CAR T-cell expansion: 4-5 weeks.
    Confirmation of CAR expression, IFN-gamma ELISA, and cytotoxicity assay of transduced and expanded T-cells: 2 weeks.

  • While the success rate of stable cell line generation is highly dependent on the target genes and Syd Labs can not guarantee 100% success rate, our in-house data show a success rate greater than 90%.

    Fast turnaround of stable cell line development: 6-7 weeks.

    We have a lot of experience in dealing with difficult-to-express proteins.

  • Biologics production stable cell line development services utilize advanced technology platforms to generate cell lines expressing the target gene at very high levels for the manufacturing of recombinant proteins and antibodies.

    - Performed under GLP; manufactured product may be used in FDA Nonclinical Laboratory Studies.
    - Parental cell line is cGMP banked with certification.
    - Set licensing fee arrangement for commercial production license.
    - Cell lineage history of the cell line and testing details facilitate IND filing.

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