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Services for synthesis, detection, identification, separation, purification, production, quantification, and modification of oligonucleotides, RNA, DNA, peptides, and proteins, such as peptide synthesis, gene synthesis, DNA cloning and subcloning, protein expression, custom antibody development, cell line generation, cell and tissue culture, and cell-based assays.
    86 Services
  • One-stop sequence optimization, gene synthesis, and DNA subcloning services.
    Various bacterial expression vectors developed by ourselves or our partners.

    Fast turnaround: 6-7 weeks.

    We have a lot of experience in dealing with difficult-to-express proteins.
    While the success rate of stable cell line generation is highly dependent on the target genes and Syd Labs can not guarantee 100% success rate, our in-house data show a success rate greater than 90%.

  • Fast turnaround: 3-6 months with our proprietary optimization algorithm.

    Antibody affinity can be improved by about 10 folds after each round of antibody affinity maturation.

  • Experienced scientists working on antibody and cell line development services for decades. >90% success rate of stable cell line generation.

    Stable cell lines developed with our proprietary recombinant antibody expression system with multiple selectable markers is very productive in expressing target proteins.

    Fast turnaround:

    Basic service: 7-8 weeks.
    Premium service: 12-14 weeks.
    Pool cells: 6 weeks.

  • Biologics production stable cell line development services utilize advanced technology platforms to generate cell lines expressing the target gene at very high levels for the manufacturing of recombinant proteins and antibodies.

    - Performed under GLP; manufactured product may be used in FDA Nonclinical Laboratory Studies.
    - Parental cell line is cGMP banked with certification.
    - Set licensing fee arrangement for commercial production license.
    - Cell lineage history of the cell line and testing details facilitate IND filing.

  • Experienced scientists working on protein engineering, expression, and purification, and cell line development services for decades. >90% success rate of stable cell line generation.

    Stable cell lines developed with our proprietary protein expression system with multiple selectable markers is very productive in expressing target proteins.

    Fast turnaround:

    1 week for synthesizing a gene for expressing the target protein.
    1 week for molecular construction of the gene.
    5-6 weeks for generation of suspension CHO stable cell lines expressing the target protein.
    5-6 weeks for additional services included in the premium package.

  • Denaturation and reduction followed by LC-MS (liquid chromatography-mass spectrometry) analysis.

    Fast turnaround time: 1- 2 weeks.

    Sample requirement: >100 ug at 1 mg/ml.

  • Peptide mapping by LC-MS/MS can be used to determine detailed information about the peptide's sequence and post-translational modifications.
     

  • Capillary electrophoresis (CE) analysis using Caliper LC90.

    Sample requirement: 50-100 ug.

    Fast turnaround time: 1 - 2 weeks.

  • Capillary isoelectric focusing is an analytical technique for characterization of protein mixtures and determination of protein isoelectric points.

    Sample requirement: 50-100 ug.

    Fast turnaround time: 1 - 2 weeks.

  • Sample requirement: 50-100 ug.

    Fast turnaround time: 1 - 2 weeks.

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