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Services for synthesis, detection, identification, separation, purification, production, quantification, and modification of oligonucleotides, RNA, DNA, peptides, and proteins, such as peptide synthesis, gene synthesis, DNA cloning and subcloning, protein expression, custom antibody development, cell line generation, cell and tissue culture, and cell-based assays.
    86 Services
  • The antibody variable regions of both heavy chain (VH) and light chain (VL) are analyzed for liabilities including, but not limited to N-linked glycosylation, deamidation, isomerization, pyroglutamate formation, and oxidation.

    Fast turnaround time: 1 week per antibody, but may require more time depending on the complexity of analysis.

  • N-terminal Edman sequencing of proteins or peptides can be used to determine the N-terminal amino acid residues of purified protein samples in addition to cleavage sites, and to identify an unknown protein or confirm the identity of a known protein, or to design oligonucleotide probes.

    High sensitivity: even with picomoles of protein.

    Various formats: in solution, gels or on PVDF blots.

    Fast turnaround time: 1-2 weeks per sample, but may require more time depending on the complexity of analysis.

  • Kinetic analysis is used to determine the affinity of an antibody to its soluble antigen using surface plasmon resonance (SPR) or biolayer interferometry (BLI), which can measure kon, koff, and kD. Association and dissociation are measured on the Biacore T100 or the ForteBio Octet QKe using various concentrations of the antigen and the kD is calculated using an appropriate curve-fitting model.

    Fast turnaround time: 2-3 days per antibody-antigen pair, but may require more time depending on the complexity of analysis.

  • We may synthesize codon-optimized cDNA, gene variants, artificially designed DNA, or any other sequence for your research.
    Fast turnaround: 10 days.

    One-stop gene synthesis and DNA subcloning.
    Various mammalian expression vectors developed by ourselves or our partners.
    Free sequence optimization to meet your goals such as protein expression at high and reliable levels.

  • Small to large scale of in vivo ascites production service starting with mouse and rat hybridomas.

  • Small to large scale production of monoclonal antibodies and recombinant proteins using mammalian cell culture of hybridoma, CHO, NSO, and HEK-293 cells.

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