APIM050289: AB-680

CAS No.: 2105904-82-1.
Purity: >99% by Achiral and Chiral HPLCs.
QC: Achiral and Chiral HPLCs, MS, NMR, and Quantitative Elemental Analysis Report.
Solubility: Refer to Certificate of Analysis.

C039P: Abciximab Biosimilar (Research Grade), Anti-human Glycoprotein IIb/IIIa Receptor Monoclonal Antibody

Recombinant Humanized IgG1 Monoclonal Antibody.
Specificity/Sensitivity: The monoclonal antibody abciximab biosimilar specifically binds to the human Glycoprotein IIb/IIIa Receptor protein.
Applications: ELISA, flow cytometry, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by abciximab.

C003P: Adalimumab Biosimilar, TNF alpha Monoclonal Antibody

Recombinant Humanized IgG1 Monoclonal Antibody.
Specificity/Sensitivity: The monoclonal antibody adalimumab biosimilar specifically binds to the human TNF alpha.
Applications: ELISA, flow cytometry, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by adalimumab.

C040P: Alemtuzumab Biosimilar, CD52 Monoclonal Antibody

Recombinant Humanized IgG1 Monoclonal Antibody.
Specificity/Sensitivity: The monoclonal antibody alemtuzumab biosimilar specifically binds to the human CD52, a protein present on the surface of mature lymphocytes.
Applications: ELISA, flow cytometry, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by alemtuzumab.

PA007573.m2a:In Vivo Grade Recombinant Anti-human CD25 (IL-2R alpha) Monoclonal Antibody (Clone: 7G7B6), Mouse IgG2a Kappa

Recombinant mouse Igg2a Monoclonal Antibody.
Specificity/Sensitivity: The in vivo grade recombinant mouse monoclonal antibody (clone: 7G7B6) specifically binds to human CD25 (IL-2R alpha).
Applications:ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the human CD25 (IL-2R alpha) protein.

PA007481.m1: Recombinant Anti-human CD28 Monoclonal Antibody (Clone: CD28.2), Mouse IgG1 Kappa

Recombinant mouse IgG1 Monoclonal Antibody.
Conjugation: Non-conjugated.
Specificity/Sensitivity: The recombinant CD28.2 antibody specifically binds to human CD28.
Applications: Flow cytometry (FC), and Immunohistochemistry - Frozen (IHC-F).

PA007481.h1Fs: Recombinant Anti-human CD28 Monoclonal Antibody (Clone: CD28.2), Human IgG1 Fc Silent Kappa

Recombinant human IgG1 Monoclonal Antibody with Fc silent mutation.
Conjugation: Non-conjugated.
Specificity/Sensitivity: The recombinant CD28.2 antibody specifically binds to human CD28.
Applications: Flow cytometry (FC), and Immunohistochemistry - Frozen (IHC-F).

PA007764.h1Fs-b: Biotinylated Recombinant Anti-human CD28 Monoclonal Antibody (Clone: CD28.2), Human IgG1 Fc Silent Kappa

Recombinant  human IgG1 monoclonal antibody with site-directed biotinylation through the Avi tag at the C-terminus of the antibody heavy chain. 
Conjugation: Biotin-conjugated.
Specificity/Sensitivity: The site-directed biotinylated recombinant CD28.2 antibody specifically binds to human CD28.
Applications: Flow cytometry (FC) with various dye conjugation through streptavidin; conjugation to streptavidin agarose beads or streptavidin magnetic beads.

PA007222.m1: Non-conjugated Recombinant Anti-human CD3e Monoclonal Antibody (Clone: UCHT1), Mouse IgG1 Kappa

Recombinant mouse IgG1 Monoclonal Antibody.
Conjugation: non-conjugated.
Specificity/Sensitivity: The recombinant mouse monoclonal antibody (clone: UCHT1) specifically binds to the human T cell receptor CD3.
Applications: Flow cytometry (FC), and Immunohistochemistry - Frozen (IHC-F).
 

PA007222.h1Fs: Non-conjugated Recombinant Anti-human CD3e Monoclonal Antibody (Clone: UCHT1), Human IgG1 Fc Silent Kappa

Recombinant human IgG1 Monoclonal Antibody with Fc silent mutation.
Conjugation: non-conjugated.
Specificity/Sensitivity: The recombinant UCHT1 antibody specifically binds to the human T cell receptor CD3.
Applications: Flow cytometry (FC), and Immunohistochemistry - Frozen (IHC-F).
 

PA007223.h1Fs-b: Biotinylated Recombinant Anti-human CD3e Monoclonal Antibody (Clone: UCHT1), Human IgG1 Fc Silent Kappa

Recombinant human IgG1 monoclonal antibody with site-directed biotinylation through the Avi tag at the C-terminus of the antibody heavy chain.
Conjugation: biotin-conjugated.
Specificity/Sensitivity: The site-directed biotinylated recombinant UCHT1 antibody specifically binds to the human T cell receptor CD3.
Applications:  Flow cytometry (FC) with various dye conjugation through streptavidin; conjugation to streptavidin agarose beads or streptavidin magnetic beads.

PA007385.m1: In vivo Grade Recombinant Anti-human CD4 Monoclonal Antibody, Mouse IgG1 Kappa (Clone: 13B8.2)

Recombinant mouse IgG1 Monoclonal Antibody. 
Specificity/Sensitivity: The in vivo grade recombinant mouse monoclonal antibody (clone: 13B8.2) specifically binds to human CD4.
Applications: ELISA, flow cytometry, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the human CD4 protein.

PA007156.m2c: In vivo Grade Recombinant Anti-mouse CD25 Monoclonal Antibody (Clone PC61.5.3), Mouse IgG2c Kappa

The in vivo grade recombinant anti-mouse CD25 mouse IgG2c monoclonal antibody was produced in CHO cells.
Applications: immunoprecipitation (IP), immunohistochemistry (IHC), Flow Cytometry (FC), and various functional assays, such as in vivo depletion of CD25+CD4+ Treg cells, in vitro blocking of IL-2 binding to low- and high-affinity receptors, and growth inhibition of IL-2-dependent T-cell lines.
Endotoxin Level: Less than 1 EU/mg of protein as determined by LAL method.

PA007156.m2caf: In vivo Grade Recombinant Afucosylated Anti-mouse CD25 Monoclonal Antibody (Clone PC61.5.3), Mouse IgG2c Kappa

The in vivo grade recombinant afucosylated anti-mouse CD25 mouse IgG2c monoclonal antibody was produced in engineered CHO cells which produce afucosylated antibodies.
Applications: immunoprecipitation (IP), immunohistochemistry (IHC), Flow Cytometry (FC), and various functional assays, such as in vivo depletion of CD25+CD4+ Treg cells, in vitro blocking of IL-2 binding to low- and high-affinity receptors, and growth inhibition of IL-2-dependent T-cell lines.
Endotoxin Level: Less than 1 EU/mg of protein as determined by LAL method.

PA007489.r1: Recombinant Anti-mouse CD25 Monoclonal Antibody (Clone: PC61.5.3), Rat IgG1 Lambda

Recombinant Rat IgG1 Monoclonal Antibody. 
Conjugation: Non-conjugated.
Specificity/Sensitivity: The recombinant PC61.5.3 antibody specifically binds to mouse CD25 protein.
Applications: Flow cytometry (FC), and Immunohistochemistry - Frozen (IHC-F). 

PA007489.h1Fs: Recombinant Anti-mouse CD25 Monoclonal Antibody (Clone: PC61.5.3), Human IgG1 Fc Silent Kappa

Recombinant  human IgG1 Monoclonal Antibody with Fc silent mutation. 
Conjugation: Non-conjugated.
Specificity/Sensitivity: The recombinant PC61.5.3 antibody specifically binds to mouse CD25 protein.
Applications: Flow cytometry (FC), and Immunohistochemistry - Frozen (IHC-F).

PA007718.h1Fs-b: Biotinylated Recombinant Anti-mouse CD25 Monoclonal Antibody (Clone: PC61.5.3), Human IgG1 Fc Silent Kappa

Recombinant human IgG1 Monoclonal Antibody with site-directed biotinylation through the Avi tag at the C-terminus of the antibody heavy chain.
Conjugation: Biotin-conjugated.
Specificity/Sensitivity: The site-directed biotinylated recombinant PC61.5.3 antibody specifically binds to mouse CD25 protein.
Applications: Flow cytometry (FC) with various dye conjugation through streptavidin; conjugation to streptavidin agarose beads or streptavidin magnetic beads.