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Home > Antibodies > Anti-Human Antibodies for Flow Cytometry > Anti-Human CD4 Monoclonal Antibodies for Flow Cytometry

Anti-Human CD4 Monoclonal Antibodies for Flow Cytometry

cluster of differentiation 4, leu-3, T4

Catalog No. Product Name Size List Price (US$) Quantity
PA007416.m1 Recombinant Anti-human CD4 Monoclonal Antibody (Clone: SK3 / Anti-Leu 3a), Mouse IgG1 Kappa 50 ug 25.00
PA007416.m1 Recombinant Anti-human CD4 Monoclonal Antibody (Clone: SK3 / Anti-Leu 3a), Mouse IgG1 Kappa 200 ug 45.00
PA007416.h1Fs Recombinant Anti-human CD4 Monoclonal Antibody (Clone: SK3 / Anti-Leu 3a), Human IgG1 Fc Silent Kappa 50 ug 50.00
PA007416.h1Fs Recombinant Anti-human CD4 Monoclonal Antibody (Clone: SK3 / Anti-Leu 3a), Human IgG1 Fc Silent Kappa 200 ug 90.00
PA007759.h1Fs-b Biotinylated Recombinant Anti-human CD4 Monoclonal Antibody (Clone: SK3 / Anti-Leu 3a), Human IgG1 Fc Silent Kappa 50 ug 45.00
PA007759.h1Fs-b Biotinylated Recombinant Anti-human CD4 Monoclonal Antibody (Clone: SK3 / Anti-Leu 3a), Human IgG1 Fc Silent Kappa 200 ug 90.00
Description

PA007416.m1: Non-conjugated Recombinant Anti-human CD4 Monoclonal Antibody (Clone: SK3 / Anti-Leu 3a), Mouse IgG1 Kappa

Recombinant  Mouse IgG1 Monoclonal Antibody. 
Clone: SK3 / Anti-Leu 3a.
Isotype:  Mouse IgG1 kappa.
Source: The anti-human CD4 monoclonal antibody (clone: SK3 / Anti-Leu 3a) was produced in mammalian cells.
Conjugation: Non-conjugated.
Specificity/Sensitivity: The recombinant SK3 / Anti-Leu 3a antibody specifically binds to human CD4.
Applications: Flow cytometry (FC), and Immunohistochemistry - Frozen (IHC-F). 
Form of Antibody: 0.2 uM filtered solution, pH 7.4, no stabilizers or preservatives.
Purity: >95% by SDS-PAGE under reducing conditions.

PA007416.h1Fs: Non-conjugated Recombinant Anti-human CD4 Monoclonal Antibody (Clone: SK3 / Anti-Leu 3a), Human IgG1 Fc Silent Kappa

Recombinant  Human IgG1 Monoclonal Antibody with Fc silent mutation. 
Clone: SK3 / Anti-Leu 3a.
Isotype: Human IgG1 kappa.
Source: The anti-human CD4 monoclonal antibody (clone: SK3 / Anti-Leu 3a) was produced in mammalian cells.
Conjugation: Non-conjugated.
Specificity/Sensitivity: The recombinant SK3 / Anti-Leu 3a antibody specifically binds to human CD4.
Applications: Flow cytometry (FC), and Immunohistochemistry - Frozen (IHC-F). 
Form of Antibody: 0.2 uM filtered solution, pH 7.4, no stabilizers or preservatives.
Purity: >95% by SDS-PAGE under reducing conditions.

PA007759.h1Fs-b: Biotinylated Recombinant Anti-human CD4 Monoclonal Antibody (Clone: SK3 / Anti-Leu 3a), Human IgG1 Fc Silent Kappa

Recombinant  human IgG1 monoclonal antibody with site-directed biotinylation through the Avi tag at the C-terminus of the antibody heavy chain.
Clone: SK3 / Anti-Leu 3a.
Isotype:  Human IgG1 Fc Silent Kappa.
Source: The site-directed biotinylated anti-human CD4 monoclonal antibody (clone: SK3 / Anti-Leu 3a) was produced in mammalian cells.
Conjugation: Biotin-conjugated.
Specificity/Sensitivity: The site-directed biotinylated recombinant SK3 / Anti-Leu 3a antibody specifically binds to human CD4.
Applications: Flow cytometry (FC) with various dye conjugation through streptavidin; conjugation to streptavidin agarose beads or streptavidin magnetic beads.
Form of Antibody: 0.2 uM filtered solution, pH 7.4, no stabilizers or preservatives.
Purity: >95% by SDS-PAGE under reducing conditions.

Shipping: The SK3 / Anti-Leu 3a antibody is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 
12 months from date of receipt, -20 to -70°C as supplied.
1 month from date of receipt, 2 to 8°C as supplied.

Background:

The recombinant SK3 / Anti-Leu 3a antibody binds to the human CD4 protein (cluster of differentiation 4), a glycoprotein and the co-receptor for the T-cell receptor (TCR). The CD4 protein is expressed on the surface of immune cells such as helper T cells, monocytes, macrophages, and dendritic cells.

References of Anti-Human CD4 Monoclonal Antibody (Clone: SK3 / Anti-Leu 3a)

Hirahara, K., et al. Int Immunol. 2016 Apr;28(4):163-71. doi: 10.1093/intimm/dxw006. PMID: 26969728
The SK3 antibody (anti-human CD4, Leu 3a) was used in flow cytometry to identify CD4+ T-helper subsets in human peripheral blood mononuclear cells. SK3 staining enabled accurate gating of CD4+ cells, revealing distinct cytokine profiles in inflammatory conditions and highlighting novel therapeutic targets for autoimmune diseases.
(Tags: activity of SK3 / Anti-Leu 3a antibody; function of SK3 / Anti-Leu 3a antibody)
For more technical references or data sheets regarding the Anti-Human CD4 Monoclonal Antibody (Clone: SK3 / Anti-Leu 3a) formats, please contact our scientific support team at message@sydlabs.com.

Syd Labs provides the following in vivo grade recombinant anti-mouse CD4 monoclonal antibodies:
Recombinant Anti-mouse CD4 monoclonal antibody (Clone: GK1.5)
Recombinant Anti-mouse CD4 monoclonal antibody (Clone: YTS191)
Recombinant Anti-mouse CD4 monoclonal antibody (Clone: YTS 177.9.6.1)
Recombinant Anti-mouse CD4 monoclonal antibody (Clone: YTA 3.1.2)

Syd Labs provides the following in vivo grade recombinant anti-human CD4 monoclonal antibodies:
Recombinant Anti-human CD4 monoclonal antibody (Clone: SK3 / Anti-Leu 3a)
Recombinant Anti-human CD4 monoclonal antibody (Clone: OKT4)
Recombinant Anti-human CD4 monoclonal antibody (Clone: 13B8.2)
Recombinant Anti-human CD4 monoclonal antibody (Clone: OKT4A)
Clenoliximab biosimilar, research grade, anti-human CD4 monoclonal antibody
Ibalizumab biosimilar, research grade, anti-human CD4 monoclonal antibody

Syd Labs provides the following recombinant anti-mouse CD4 monoclonal antibodies for flow cytometry:
Recombinant Anti-mouse CD4 monoclonal antibody (Clone: GK1.5) for flow cytometry

Syd Labs provides the following recombinant anti-human CD4 monoclonal antibodies for flow cytometry:
Recombinant Anti-human CD4 monoclonal antibody (Clone: SK3 / Anti-Leu 3a) for flow cytometry
Recombinant Anti-human CD4 monoclonal antibody (Clone: OKT4) for flow cytometry
Recombinant Anti-human CD4 monoclonal antibody (Clone: 13B8.2) for flow cytometry
Recombinant Anti-human CD4 monoclonal antibody (Clone: OKT4A) for flow cytometry

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