C105P: Evolocumab Biosimilar, PCSK9 Monoclonal Antibody
Recombinant fully human IgG2 monoclonal antibody.
Specificity/Sensitivity: The monoclonal antibody evolocumab biosimilar specifically binds to the human PCSK9.
Applications: ELISA, flow cytometry, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by evolocumab.C049P: Gemtuzumab Biosimilar, CD33 Monoclonal Antibody
Recombinant Humanized IgG4 Monoclonal Antibody.
Specificity/Sensitivity: The in vivo grade gemtuzumab biosimilar specifically binds to the human CD33 protein.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by gemtuzumab.C009: Herceptin Biosimilar Stable Cell Line (CHO)
The yield of Herceptin biosimilar from the CHO stable cell line was above 2.0 g/L in a 3 liter manufacturing.
C106P: Ifinatamab Biosimilar, B7-H3 Monoclonal Antibody
Recombinant Humanized IgG1 Monoclonal Antibody.
Specificity/Sensitivity: The research grade ifinatamab biosimilar specifically binds to the human B7-H3 (CD276) protein.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by ifinatamab.C011P: Infliximab Biosimilar, TNF alpha Monoclonal Antibody
Recombinant Humanized IgG1 Monoclonal Antibody.
Specificity/Sensitivity: The monoclonal antibody Infliximab biosimilar specifically binds to the human TNF alpha.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by Infliximab.C020P: Omalizumab Biosimilar, Human IgE Monoclonal Antibody
Recombinant Humanized IgG1 Monoclonal Antibody.
Specificity/Sensitivity: The monoclonal antibody Omalizumab specifically binds to the human immunoglobulin E (IgE) free in the blood and interstitial fluid and to membrane-bound form of IgE (mIgE) on the surface of mIgE-expressing B lymphocytes. It does not bind to IgE that is already bound by the high affinity IgE receptor (FcεRI) on the surface of mast cells, basophils, and antigen-presenting dendritic cells.
Applications: Functional assay, neutralization, blocking, ELISA.C021P: Palivizumab Biosimilar, RSV Monoclonal Antibody
Recombinant Humanized IgG1 Monoclonal Antibody.
Specificity/Sensitivity: The monoclonal antibody palivizumab biosimilar specifically binds to an epitope in the A antigenic site of the F protein of RSV (respiratory syncytial virus).
Applications: ELISA, neutralization, functional assays.C012P: Panitumumab Biosimilar, Human EGFR/ErbB-1/HER1 Monoclonal Antibody
Recombinant Humanized IgG2 Monoclonal Antibody.
Specificity/Sensitivity: The monoclonal antibody panitumumab biosimilar specifically binds to the human EGFR, ErbB-1 and HER1.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by panitumumab.C006: Perjeta / Omnitarg Biosimilar Stable Cell Line (CHO)
The yield of Perjeta / Omnitarg biosimilar from the CHO stable cell line was above 3.0 g/L in a 3 liter manufacturing.
C006P: Pertuzumab Biosimilar, Human HER2 Monoclonal Antibody
Recombinant Humanized IgG1 Monoclonal Antibody.
Specificity/Sensitivity: The monoclonal antibody pertuzumab biosimilar specifically binds to the human HER2/ErbB-2/c-neu.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by pertuzumab.