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Infliximab Biosimilar, TNF alpha Monoclonal Antibody

Anti-TNF alpha Chimeric Monoclonal Antibody

Catalog No. Product Name Size List Price (US$) Quantity
C011P Infliximab Biosimilar, TNF alpha Monoclonal Antibody 10 mg 500.00
C011P Infliximab Biosimilar, TNF alpha Monoclonal Antibody 50 mg 750.00
C011P Infliximab Biosimilar, TNF alpha Monoclonal Antibody 100 mg 1000.00
C011P Infliximab Biosimilar, TNF alpha Monoclonal Antibody 1 g 3000.00
Description

C011P: Infliximab Biosimilar, TNF alpha Monoclonal Antibody

Recombinant Chimeric IgG1 Monoclonal Antibody.
Isotype: Human IgG1 kappa.
Source: The monoclonal antibody Infliximab biosimilar was produced in the Infliximab biosimilar CHO stable cell line.
Specificity/Sensitivity: The monoclonal antibody Infliximab biosimilar specifically binds to the human TNF alpha.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by Infliximab.
Form of Antibody: 0.2 uM filtered solution, pH 7.2, no stabilizers or preservatives.
Endotoxin: < 0.1 EU per 1 ug of the protein by the LAL method.
Purity: >95% by SDS-PAGE under reducing conditions and HPLC.

Shipping: The monoclonal antibody Infliximab biosimilar is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month from date of receipt, 2 to 8°C as supplied.

Background

Infliximab, a chimeric anti-TNF-α monoclonal antibody, is used to treat psoriasis, Crohn's disease, ankylosing spondylitis, psoriatic arthritis, rheumatoid arthritis, and ulcerative colitis. Infliximab interferes TNF-α from binding to its receptor in the cell.

Mainly produced by activated macrophages (M1), Tumor necrosis factor (TNF, cachexin, cachectin, tumor necrosis factor alpha, TNFα) plays important roles in the regulation of autoimmune reaction.

Syd Labs also provides the following anti-TNF antibody biosimilar protein:
Adalimumab Biosimilar, research grade

Syd Labs also provides the following research grade antibody biosimilar proteins:
Bevacizumab Biosimilar, research grade (VEGF-A)
Ranibizumab Biosimilar, research grade (VEGF-A, Fab produced in E. coli)
Cetuximab Biosimilar, research grade (HER1, ErbB-1, EGFR)
Panitumumab Biosimilar, research grade (HER1, ErbB-1, EGFR)
Trastuzumab Biosimilar, research grade (HER2, ErbB-2, c-neu)
Pertuzumab Biosimilar, research grade (HER2, ErbB-2, c-neu)
Infliximab biosimilar, research grade (TNF alpha)
Adalimumab biosimilar, research grade (TNF alpha)
Rituximab biosimilar, research grade (CD20)
Denosumab biosimilar, research grade (RANKL, RANK ligand, OPGL, TNFSF11, CD254, TRANCE, ODF)
Palivizumab Biosimilar, research grade (RSV)
Omalizumab biosimilar, research grade (IgE)
Eculizumab biosimilar, research grade (C5)

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