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Conditions of optimal DMT-2'-O-MOE-A(Bz)-CE-Phosphoramidite performance should be determined experimentally by the investigator. Its precursors, 2'-O-MOE-A (CAS # 168427-74-5) and N6-Bz-2'-O-MOE-5'-O-DMT-A (CAS # 251647-48-0), are available.
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APIM050512: DMT-2'-O-MOE-A(Bz)-CE-Phosphoramidite
CAS No.: 251647-53-7.
Molecular Formula: C50H58N7O9P.
Molecular Weight: 932.03.
Appearance: (visual inspection) white to off-white powder.
Identity: (molecular weight by MS) conforms to structure molecular weight; (1H NMR) conforms to structure.
Purity: (31P NMR) ≥99.0%; (RP-HPLC) ≥99.0%.
Impurity profile: (HPLC) any single critical impurity ≤ 0.15%; total critical impurities ≤ 0.3%; total impurities ≤ 1.0%.
Assay: (HPLC) 98.0%~102.0%.
Sulfate ash: (muffle furnace) ≤0.1%.
Residual solven: (GC) ≤1.5%.
Moisture content: (Karl Fischer) ≤0.2%
Clarity of solution: (visual inspection) the solution shall be clear and free of insoluble substances.
Storage: -20±5℃.
2-MOE-Phosphoramidites:
DMT-2'-O-MOE-A(Bz)-CE-Phosphoramidite (CAS No.: 251647-53-7)
DMT-2'-O-MOE-G(iBu)-CE-Phosphoramidite (CAS No.: 251647-55-9)
5-Me-DMT-2'-O-MOE-C(Bz)-CE-Phosphoramidite(CAS No.: 163759-94-2)
DMT-2'-O-MOE-T-CE-Phosphoramidite (CAS No.: 163878-63-5)
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