C020P: Omalizumab Biosimilar, Human IgE Monoclonal Antibody
Recombinant Humanized IgG1 Monoclonal Antibody.
Specificity/Sensitivity: The monoclonal antibody Omalizumab specifically binds to the human immunoglobulin E (IgE) free in the blood and interstitial fluid and to membrane-bound form of IgE (mIgE) on the surface of mIgE-expressing B lymphocytes. It does not bind to IgE that is already bound by the high affinity IgE receptor (FcεRI) on the surface of mast cells, basophils, and antigen-presenting dendritic cells.
Applications: Functional assay, neutralization, blocking, ELISA.C021P: Palivizumab Biosimilar, RSV Monoclonal Antibody
Recombinant Humanized IgG1 Monoclonal Antibody.
Specificity/Sensitivity: The monoclonal antibody palivizumab biosimilar specifically binds to an epitope in the A antigenic site of the F protein of RSV (respiratory syncytial virus).
Applications: ELISA, neutralization, functional assays.C012P: Panitumumab Biosimilar, Human EGFR/ErbB-1/HER1 Monoclonal Antibody
Recombinant Humanized IgG2 Monoclonal Antibody.
Specificity/Sensitivity: The monoclonal antibody panitumumab biosimilar specifically binds to the human EGFR, ErbB-1 and HER1.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by panitumumab.C006P: Pertuzumab Biosimilar, Human HER2 Monoclonal Antibody
Recombinant Humanized IgG1 Monoclonal Antibody.
Specificity/Sensitivity: The monoclonal antibody pertuzumab biosimilar specifically binds to the human HER2/ErbB-2/c-neu.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by pertuzumab.C061P: Ramucirumab Biosimilar, Human VEGFR2 Monoclonal Antibody
Recombinant Human IgG1 Monoclonal Antibody.
Specificity/Sensitivity: The monoclonal antibody ramucirumab biosimilar specifically binds to the human VEGFR2 (KDR).
Applications: ELISA, flow cytometry, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by ramucirumab.C005P: Ranibizumab Biosimilar, Human VEGF Monoclonal Antibody Fragment (Fab)
Recombinant Humanized Monoclonal Antibody Fragment (Fab) generated from the same parent mouse antibody as bevacizumab.
Specificity/Sensitivity: The research grade Fab protein ranibizumab specifically binds to the human VEGF-A.
Applications: Functional assay, neutralization.BP000050-GD13: Recombinant Human RANKL Protein
Source:E. coli-derived.
The RANKL / TNFSF11 / TRANCE / OPGL / CD254 activity is calculated by its ability to induce osteoclast differentiation on RAW 264.7 mouse macrophages. The ED50 for this effect is 2-12 ng/ml.
Endotoxin Level: <1.0 EU per ug of the protein by the LAL method.
Purity > 95%, by SDS-PAGE and SEC-HPLC.C010P: Rituximab Biosimilar, CD20 Monoclonal Antibody
Recombinant Humanized IgG1 Monoclonal Antibody.
Specificity/Sensitivity: The monoclonal antibody rituximab biosimilar specifically binds to the human TNF alpha.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by rituximab.C034P: Secukinumab Biosimilar, Human IL17A Monoclonal Antibody
Recombinant fully human IgG1 monoclonal antibody.
Specificity/Sensitivity: The monoclonal antibody Secukinumab biosimilar specifically binds to the human IL17A.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by Secukinumab.BP000173-CYT-320: Recombinant Mouse RANK Ligand Soluble
Source: E. coli-derived.
A single, non-glycosylated, polypeptide chain containing 174 amino acids and having a total molecular mass of 19.9 kDa.
Measured by its ability to induce osteoclast formation on murine RAW264.7 cells using a concentration of 5.0-10.0 ug/ml, corresponding to a specific activity of 100,000-200,000 Units/mg.
Purity > 95%, by SDS-PAGE and RP-HPLC.