PA007512.m1: In Vivo Grade Recombinant Anti-mouse/human/rat/monkey/hamster/canine/bovine TGF-β Monoclonal Antibody (Clone: 1D11.16.8), Mouse IgG1 Kappa

The in vivo grade recombinant anti-mouse/human/rat/monkey/hamster/canine/bovine TGF-β mouse IgG1 kappa monoclonal antibody was produced in mammalian cells. 
Specificity/Sensitivity: The in vivo grade recombinant mouse monoclonal antibody (clone: 1D11.16.8) specifically binds to mouse/human/rat/monkey/hamster/canine/bovine TGF-β.
Applications: ELISA, flow cytometry, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the TGF-β protein.

BP004232: Mouse Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein with the C-His Tag

Source: The recombinant Mouse Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein, (amino acids Phe31-Val988(ITGAV)acidic tail & Gly22-Asn706(ITGB6)basic tail) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Mouse ITGAV&ITGB6 protein with the C-His tag at 1 ug/ml (100 ul/Well) on the plate. Dose response curve for the recombinant Biotinylated Human Latent TGF beta 1 protein with the C-His tag with the EC50 of 41.8 ng/ml determined by ELISA (QC Test).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP004141: Mouse Integrin alpha V beta 8 (ITGAV&ITGB8) Heterodimer Protein with the C-His Tag

Source: The recombinant Mouse Integrin alpha V beta 8 (ITGAV&ITGB8) Heterodimer Protein, (amino acids Phe31-Val988(ITGAV)acidic tail & Gly22-Ser679(ITGB8)basic tail) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Mouse ITGAV&ITGB8 protein with the C-His tag at 5 ug/ml (100 ul/Well) on the plate. Dose response curve for the recombinant Biotinylated Human Latent TGF beta 1 protein with the C-His tag with the EC50 of 0.97 ug/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP005189: Human Integrin alpha V beta 8 (ITGAV&ITGB8) Heterodimer Protein with the C-His-Avi Tag

Source: The recombinant Human Integrin alpha V beta 8 (ITGAV&ITGB8) Heterodimer Protein, (amino acids Phe31-Val992(ITGAV) acidic tail & Glu43-Arg684(ITGB8) basic tail) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human ITGAV&ITGB8 protein with the C-His-Avi tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Biotinylated Human Latent TGF beta 1 protein with the C-His tag with the EC50 of 0.85 ug/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP005288: Human Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein with the C-His-Avi Tag

Source: The recombinant Human Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein, (amino acids Phe31-Val992(ITGAV) acidic tail & Gly22-Asn707(ITGB6) basic tail) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human ITGAV&ITGB6 protein with the C-His-Avi tag at 2 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Biotinylated Human Latent TGF beta 1 protein with the C-His tag with the EC50 of 63.3 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP003882: Human GARP&Latent TGF Beta 2 Complex Protein with the C-His-Avi Tag

Source: The recombinant Human GARP&Latent TGF Beta 2 Complex Protein, (amino acids His20-Leu628(GARP) & Leu21-Ser414(Latent TGF Beta 2)) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity:
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP003955: Biotinylated Human Integrin alpha V beta 8 (ITGAV&ITGB8) Heterodimer Protein with the C-His-Avi Tag

Source: The recombinant Biotinylated Human Integrin alpha V beta 8 (ITGAV&ITGB8) Heterodimer Protein, (amino acids Phe31-Val992(ITGAV) acidic tail & Glu43-Arg684(ITGB8) basic tail) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human Latent TGF beta 1 protein with the C-His-Avi tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Biotinylated Human ITGAV&ITGB8 protein with the C-His tag with the EC50 of 9.62 ug/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP004118: Biotinylated Human Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein with the C-His-Avi Tag

Source: The recombinant Biotinylated Human Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein, (amino acids Phe31-Val992(ITGAV) acidic tail & Gly22-Asn707(ITGB6) basic tail) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human Latent TGF beta 1 protein with the C-His-Avi tag at 2 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Biotinylated Human ITGAV&ITGB6 protein with the C-His tag with the EC50 of 2.2 ug/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP005248: Human TGF-beta RII/TGFBR2 Protein with the C-mFc-Avi Tag

Source: The recombinant Human TGF-beta RII/TGFBR2 Protein, (amino acids Ile24-Asp159) fused with a mFc-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human Mature TGF beta 1 protein with the C-mFc-Avi tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Human TGF-beta RII protein with the C-mFc tag with the EC50 of 3.8 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP005594: Human TGF-beta RII/TGFBR2 Protein with the N-hFc Tag

Source: The recombinant Human TGF-beta RII/TGFBR2 Protein, (amino acids Ile24-Asp159) fused with a hFc tag at the N-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human Mature TGF beta 1 protein with the N-hFc tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Human TGF-beta RII protein with the N-hFc tag with the EC50 of 11.0 ng/ml determined by ELISA (QC Test). The affinity constant of 2.21 uM as determined in SPR assay (Biacore T200).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP005169: Cynomolgus GARP&Latent TGF beta 1 Complex Protein with the C-His-Avi Tag

Source: The recombinant Cynomolgus GARP&Latent TGF beta 1 Complex Protein, (amino acids Ala18-Leu628(GARP) & Leu30-Ser390(Latent TGF beta 1)) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Cynomolgus GARP&Latent TGF beta 1 Complex protein with the C-His-Avi tag at 5 ug/ml (100 ul/Well) on the plate. Dose response curve for the recombinant Anti-GARP&Latent TGF Beta 1 Antibody protein with the C-hFc tag with the EC50 of 10.1 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.