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Home > Antibodies > Anti-Mouse Antibodies (In Vivo) > Anti-Mouse LPAM-1 Monoclonal Antibodies

Anti-Mouse LPAM-1 Monoclonal Antibodies

alpha 4 beta 7 Integrin, CD49d/beta 7, LPAM-1, ITGA4, ITGB7

Catalog No. Product Name Size List Price (US$) Quantity
PA007543.r2a In Vivo Grade Recombinant Anti-mouse LPAM-1 (Intergrin alpha 4 beta 7) Monoclonal Antibody (Clone: DATK32), Rat IgG2a Kappa 1 mg 150.00
PA007543.r2a In Vivo Grade Recombinant Anti-mouse LPAM-1 (Intergrin alpha 4 beta 7) Monoclonal Antibody (Clone: DATK32), Rat IgG2a Kappa 5 mg 350.00
PA007543.r2a In Vivo Grade Recombinant Anti-mouse LPAM-1 (Intergrin alpha 4 beta 7) Monoclonal Antibody (Clone: DATK32), Rat IgG2a Kappa 25 mg 900.00
Description

PA007543.r2a: In Vivo Grade Recombinant Anti-mouse LPAM-1 (Integrin α4β7) Monoclonal Antibody (Clone:  DATK32), Rat IgG2a Kappa

Recombinant Rat IgG2a Monoclonal Antibody.
Clone: DATK32.
Isotype: Rat IgG2a kappa.
Source: The anti-mouse LPAM-1 (Integrin α4β7) monoclonal antibody (clone: DATK32) was produced in mammalian cells.
Specificity/Sensitivity: The in vivo grade recombinant rat monoclonal antibody (clone: DATK32) specifically binds to mouse LPAM-1 (Integrin α4β7) .
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the mouse LPAM-1 (Integrin α4β7) protein.
Form of Antibody: 0.2 uM filtered solution, pH 7.4, no stabilizers or preservatives.
Endotoxin: < 1 EU per 1 mg of the protein by the LAL method.
Purity: >95% by SDS-PAGE under reducing conditions and HPLC.

Shipping: The in vivo grade recombinant anti-mouse LPAM-1 (Integrin α4β7) monoclonal antibody of clone DATK32 is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month from date of receipt, 2 to 8°C as supplied.

References of Anti-mouse LPAM-1 (Integrin α4β7) Monoclonal Antibody (Clone: DATK32)

 
 
Bemark, M., et al. Nat Commun. 2016 Sep 6;7:12698. PMID: 27596266
Expression of the gut homing α4β7 receptor (LPAM integrin) in GFP+ memory B cells, as opposed to that found in GFP− B cells or non-B cells in the PP and Spl. ...For blocking gut homing, we used the antibody clone DATK32 specific for the integrin α4β7 (Bio X Cell, West Lebanon, NH); 250µg of the antibody was injected i.p. 3 days before, on the day of and 3 days after booster immunization. ...Orally primed mice were treated with α4β7-blocking DATK32 Mab before and during p.o. or i.p. challenge immunizations with NP-CT and the number of GFP+ plasma cells in SI LP sections were determined. ...To address whether GC formation was needed for mucosal memory B-cell responses, we boosted p.o. primed mice after 6 months in the presence or absence of a GC-disrupting treatment with an anti-CD40L Mab in vivo.
(Tags: clone DATK32 of anti-mouse LPAM-1 (Integrin α4β7) mAb; DATK32 anti-mouse LPAM-1 (Integrin α4β7) antibody)
For more technical references or data sheets regarding the Anti-mouse LPAM-1 (Integrin α4β7) Monoclonal Antibody formats, please contact our scientific support team at message@sydlabs.com.
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