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Enlicitide Synthetic Peptide

Enlicitide; MK-0616; Enlicitide (MK-0616) Decanoate

Catalog No. Product Name Size List Price (US$) Quantity
C135PS Enlicitide Synthetic Peptide 20 mg 400.00
C135PS Enlicitide Synthetic Peptide 60 mg 800.00
C135PS Enlicitide Synthetic Peptide 180 mg 3200.00
Description

C135PS: Enlicitide Synthetic Peptide

Source: The enlicitide peptide was synthesized. 
Sequence: cyclo-Ala-D-Ala-Phe-Trp-Pro-Thr-Tyr-Pro-NH2 (core structure).
CAS No.: 2861205-06-1.
Molecular Formula: C92H129FN14O17.
Molecular Weight: 1722.1.
Applications: ELISA, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by enlicitide.
Form of Peptide: lyophilized, no stabilizers or preservatives.
Purity: >98% by HPLC.

Shipping: The research grade enlicitide synthetic peptide is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month from date of receipt, 2 to 8°C as supplied.

Background

What is research grade enlicitide decanoate synthetic peptide? Research-grade Enlicitide Decanoate Synthetic Peptide is a synthetic macrocyclic peptide inhibitor targeting proprotein convertase subtilisin/kexin type 9 (PCSK9), a key regulator of low-density lipoprotein receptor (LDLR) metabolism and cholesterol homeostasis. Enlicitide decanoate (MK-0616) is designed to inhibit the interaction between PCSK9 and LDLR, thereby preventing PCSK9-mediated LDL receptor degradation, promoting LDLR recycling, and enhancing cellular uptake of low-density lipoprotein cholesterol (LDL-C). As a novel peptide-based PCSK9 inhibitor, Enlicitide Decanoate features a highly constrained macrocyclic structure that enables high-affinity target binding and improved peptide stability compared with conventional linear peptides. Research-grade Enlicitide Decanoate Synthetic Peptide is widely used as a valuable tool for studying PCSK9 signaling, LDLR regulation, cholesterol metabolism, lipid homeostasis, cardiovascular biology, and next-generation peptide drug discovery. This product is supplied for research use only (RUO) and is not intended for human therapeutic applications.

Syd Labs also provides the following GLP-1 receptor agonist synthetic peptide:
Liraglutide Synthetic Peptide
Semaglutide Synthetic Peptide
Tirzepatide Synthetic Peptide

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