PA007594.r1:In Vivo Grade Recombinant Anti-human IL-12 Monoclonal Antibody (Clone: 20C2), Rat IgG1 Kappa
Recombinant Rat IgG1 Monoclonal Antibody.
Specificity/Sensitivity: The in vivo grade recombinant rat monoclonal antibody (clone: 20C2) specifically binds to human IL-12.
Applications:ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the human IL-12 protein.PA007574.r2a: In Vivo Grade Recombinant Anti-mouse IL-12 Monoclonal Antibody (Clone: R1-5D9), Rat IgG2a Kappa
Recombinant Rat IgG2a Monoclonal Antibody.
Specificity/Sensitivity: The in vivo grade recombinant rat monoclonal antibody (clone: R1-5D9) specifically binds to mouse IL-12.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the mouse IL-12 protein.PA007570.r2b: In Vivo Grade Recombinant Anti-mouse IL-12 p75 Monoclonal Antibody (Clone: R2-9A5), Rat IgG2b Kappa
Recombinant rat IgG2b Monoclonal Antibody.
Specificity/Sensitivity: The in vivo grade recombinant rat monoclonal antibody (clone: R2-9A5) specifically binds to mouse IL-12 p75.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the mouse IL-12 p75 protein.BP005012: Biotinylated Human IL-12 Protein with the C-His-Avi Tag
Source: The recombinant Biotinylated Human IL-12 Protein, (amino acids Ile23-Ser328(IL-12B) & Arg23-Ser219(IL-12A)) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Anti-IL-12 Antibody protein with the C-His-Avi tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Biotinylated Human IL-12 protein with the C-His tag with the EC50 of 10.8 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.BP003986: Cynomolgus IL-12B/p40/NKSF2 Protein with the C-His Tag
Source: The recombinant Cynomolgus IL-12B/p40/NKSF2 Protein , (amino acids Ile23-Ser328) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Cynomolgus IL-12B protein with the C-His tag at 0.5 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Anti-IL-12 Antibody protein with the C-hFc tag with the EC50 of 2.3 ng/ml determined by ELISA (QC Test).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.EK000022-EK0421: Human IL-12 (p70) ELISA Kit
Range 7.8pg/ml-500pg/ml
Sensitivity < 2 pg/ml
Specificity: no detectable cross-reactivity with any other cytokine.
Application: for quantitive detection of human IL-12(p70) in sera, plasma, body fluids, tissue lysates or cell culture supernates.
Expiration: four months at 4°C and eight months at -20°C.EK000022-EK0423: Human IL-12 (p40) ELISA Kit
Range 31.2pg/ml-2000pg/ml
Sensitivity < 2 pg/ml
Specificity: cross-reactivates with IL-12(p70), IL-23(p19/p40) < 5%.
Application: for quantitive detection of human IL-12(p40) in sera, plasma, body fluids, tissue lysates or cell culture supernates.
Expiration: four months at 4°C and eight months at -20°C.BP005622: Human IL-12 Protein with the C-His-Avi Tag
Source: The recombinant Human IL-12 Protein, (amino acids Ile23-Ser328(IL-12B) & Arg23-Ser219(IL-12A)) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human IL-12 protein with the C-His-Avi tag at 0.5 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Anti-IL-12 Antibody protein with the C-hFc tag with the EC50 of 2.1 ng/ml determined by ELISA (QC Test).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.BP005179: Human IL-12B/p40/NKSF2 Protein with the C-His Tag
Source: The recombinant Human IL-12B/p40/NKSF2 Protein, (amino acids Ile23-Ser328) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human IL-12B protein with the C-His tag at 1 ug/ml (100 ul/Well) on the plate. Dose response curve for the recombinant Anti-IL-12 Antibody protein with the C-hFc tag with the EC50 of 18.5 ng/ml determined by ELISA. The affinity constant of 98.1 nM as determined in SPR assay (Biacore T200).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.BP000135-CYT-362: Recombinant Human IL-12
Source: E. coli-derived.
It is recommended to reconstitute the lyophilized Interleukin-12 in sterile 18 M?-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Purity > 98%, by SDS-PAGE and RP-HPLC.