APIM050160: GS-9973 (ENTOSPLETINIB)
CAS No.: 1229208-44-9.
Purity: >99% Purity (HPLC, detected at 214 and 254 nm).
QC: HPLC-MS, 1HNMR, and Quantitative Elemental Analysis.
Solubility: Soluble in DMSO.APIM050161: GSK-1070916 (NMI-900)
CAS No.: 942918-07-2.
Purity: >99.5% (HPLC at 214 and 254 nm).
QC: HPLC-MS, 1HNMR, and Quatitative Elemental Analysis.
Solubility: In DMSO.APIM050162: GSK1120212 (TRAMETINIB)
CAS No.: 871700-17-3.
Purity: >99.5% (HPLC at 214 and 254 nm).
QC: MS, 1HNMR, HPLC, and quantitative elemental analysis report.
Solubility: Soluble in DMSO.APIM050164: GSK2126458 (OMIPALISIB)
CAS No.: 1086062-66-9.
Purity: >99.5% (HPLC at 214 and 254 nm).
QC: HPLC-MS, 1HNMR, and Quantitative Elemental Analysis.
Solubility: In DMSO.APIM050165: GSK2256098
CAS No.: 1224887-10-8.
Purity: >99.5% by HPLC.
QC: HPLC-MS, NMR and Quantitative Elemental Analysis.APIM050166: GSK2334470
CAS No.: 1227911-45-6.
Purity: 99.9-100% by achiral and chiral HPLCs at 214 and 254 nm. [α]20D = - 32.6 o (c 1.17, MeOH).
QC: HPLC-MS, 1HNMR, Chiral HPLC, and Quantitative Elemental Analysis Report.
Solubility: Soluble in DMSO.APIM050167: GSK2636771
CAS No.: 1372540-25-4.
Purity: >99.5% (HPLC at 214 and 254 nm).
QC: MS, 1HNMR, HPLC.
Solubility: Soluble in DMSO, and water with 1 eq. of base.APIM050168: GSK2982772
CAS No.: 1622848-92-3.
Purity: 99.9% chemical and optical purity (by achiral and chiral HPLCs).
QC: Achiral and Chiral HPLCs, 1H-NMR and Quantitative Elemental Analysis Report.
Solubility: Refer to Certificate of Analysis.APIM050169: GSK461364
CAS No.: 929095-18-1.
Purity: >99% by HPLC, 100% optical purity (Chiral HPLC).
QC: HPLC-MS, 1HNMR, Chiral HPLC, and Quantitative Elemental Analysis.
Solubility: Soluble in DMSO, and water with 2.0 eq. of HCl.APIM050170: GSK690693
CAS No.: 937174-76-0.
Purity: >99.5% chem and optical purity (HPLC and chiral HPLC at 220 nm).
QC: HPLC-MS, 1HNMR, Chiral HPLC, and Quantitative Elemental Analysis.
Solubility: In DMSO, Water with 1 eq of acid.