Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
|---|
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Background Information:
GSK2636771 is an orally bioavailable PI3K β isoform-selective inhibitor, currently in clinical trials.
Reference:
1. RA Rivero, et al, Identification of GSK2636771, a potent and selective, orally bioavailable inhibitor of phosphatidylinositol 3-kinase-beta (PI3Kβ) for the treatment of PTEN deficient tumors. Cancer Res. 2012, 72(8 Supplement), 2913.
2. RM Sanchez, et al., Synthesis and structure–activity relationships of 1,2,4-triazolo[1,5-a]pyrimidin-7(3H)-ones as novel series of potent β isoform selective phosphatidylinositol 3-kinase inhibitors. Bioorg. Med. Chem. Lett. 2012, 22(9), 3198-3202.
3. n vivo Grade. Through recrystallization and de-coloring (on Activated Carbon), the product GSK2636771 offered is a white powder, in sharp contrast to the yellow one offered by many other vendors.
APIM050167: GSK2636771
CAS No.: 1372540-25-4.
Molecular Formula: C22H22F3N3O3.
Molecular Weight: 433.4 (Refer to The Certificate of Analysis, batch-specific).
Purity: >99.5% (HPLC at 214 and 254 nm).
QC: MS, 1HNMR, HPLC.
Solubility: Soluble in DMSO, and water with 1 eq. of base.
Storage: Store at 0°C (short term), -20°C (long term), desiccated.
Copyright © 2009-2022 sydlabs.com. All rights reserved.
Use of this website means that you have read, understood, and accepted the Syd Labs Privacy Policy and Terms & Conditions.