C001: Avastin Biosimilar Stable Cell Line (CHO)
The yield of Avastin biosimilar from the CHO stable cell line was above 1.7 g/L in a 750 liter manufacturing.
C001P: Bevacizumab Biosimilar, Human VEGF Monoclonal Antibody
Recombinant Humanized IgG1 Monoclonal Antibody generated from the same parent mouse antibody as ranibizumab.
Specificity/Sensitivity: The monoclonal antibody bevacizumab biosimilar specifically binds to the human VEGF-A.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by bevacizumab.BP002885-PRO-248: Recombinant Human Endostatin Protein
Source: E. coli-derived.
The activity calculated by ECE migration inhibition was found to be 50,000 IU/mg.
Purity: > 98.0% as determined by RP-HPLC and SDS-PAGE.C005: Lucentis Biosimilar Cell Line (E. coli)
The yield of Lucentis biosimilar from E.coli was above 36 mg/L in a 7.5 liter manufacturing.
PA000228-PA1066: PLGF Polyclonal Antibody
Rabbit Polyclonal Antibody;
Applications: WB;
Reactivity: Human;
Isotype: Rabbit IgG.EK000040-EK0490: Human Placental Growth Factor ELISA Kit
Range 15.6pg/ml-1000pg/ml
Sensitivity < 1 pg/ml
Specificity: no detectable cross-reactivity with any other cytokine.
Application: for quantitive detection of human PLGF in sera, plasma, body fluids, tissue lysates or cell culture supernates.
Expiration: four months at 4°C and eight months at -20°C.C005P: Ranibizumab Biosimilar, Human VEGF Monoclonal Antibody Fragment (Fab)
Recombinant Humanized Monoclonal Antibody Fragment (Fab) generated from the same parent mouse antibody as bevacizumab.
Specificity/Sensitivity: The research grade Fab protein ranibizumab specifically binds to the human VEGF-A.
Applications: Functional assay, neutralization.BP000027-GD1: Recombinant Human VEGF165 (aa 27-191) Protein
Source: HEK 293 cell-derived.
The VEGF activity is measured in a cell proliferation assay using human umbilical vein endothelial cells (HUVEC). The ED50 for this effect is typically 1-5 ng/ml.
Endotoxin: < 1.0 EU per ug of the protein by the LAL method.
Purity: > 95% by SDS-PAGE under reducing conditions.BP000027-C083: Recombinant Human Vascular Endothelial Growth Factor Isoform 165 (VEGF165) Protein
Source: E. coli-derived.
Purity: > 95% by SEC-HPLC and reducing SDS-PAGE.
Endotoxin: < 0.1 ng/ug (1 IEU/ug).BP000027-CYT-200: Recombinant Human VEGF (121 a.a.) Protein, Sf9
Source: Sf9, Insect Cells-derived.
Determined by the dose-dependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVEC) using a concentration range of 2-5 ug/ml corresponding to a Specific Activity of 200,000-500,000 IU/mg.
Purity: >90% by SDS-PAGE and RP-HPLC.