PA007636.r2b: In Vivo Grade Recombinant Anti-mouse CD4 Monoclonal Antibody (Clone: YTA 3.1.2), Rat IgG2b Kappa

Recombinant Rat IgG2b Monoclonal Antibody.
Specificity/Sensitivity: The in vivo grade recombinant rat monoclonal antibody (clone: YTA 3.1.2) specifically binds to mouse CD4.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the mouse CD4 protein.

PA007618.m1:In Vivo Grade Recombinant Anti-human MHC Class II HLA-DP/DQ/DR Monoclonal Antibody (Clone: IVA12), Mouse IgG1 Kappa

Recombinant Mouse IgG1 Monoclonal Antibody.
Specificity/Sensitivity: The in vivo grade recombinant mouse monoclonal antibody (clone: IVA12) specifically binds to human MHC Class II HLA-DP/DQ/DR.
Applications:ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the human MHC Class II HLA-DP/DQ/DR protein.

BP005406: Human TNFR2/CD120b/TNFRSF1B Protein with the C-His Tag

Source: The recombinant Human TNFR2/CD120b/TNFRSF1B Protein, (amino acids Leu23-Asp257) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human TNFR2 protein with the C-His tag at 5 ug/ml (100 ul/Well). Dose response curve for the recombinant Biotinylated Human TNF alpha protein with the C-His tag with the EC50 of 14.6 ng/ml determined by ELISA (QC Test).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP003360: Human TNFR2/CD120b/TNFRSF1B Protein with the C-hFc Tag

Source: The recombinant Human TNFR2/CD120b/TNFRSF1B Protein, (amino acids Leu23-Asp257) fused with a hFc tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human TNF alpha protein with the C-hFc tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Human TNFR2 protein with the C-hFc tag with the EC50 of 7.1 ng/ml determined by ELISA (QC Test).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP005559: Human TNFR2/CD120b/TNFRSF1B Protein with the C-mFc Tag

Source: The recombinant Human TNFR2/CD120b/TNFRSF1B Protein, (amino acids Leu23-Asp257) fused with a mFc tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human TNF alpha protein with the C-mFc tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Human TNFR2 protein with the C-mFc tag with the EC50 of 45.8 ng/ml determined by ELISA (QC Test). The affinity constant of 1.62 nM as determined in SPR assay (Biacore T200).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP005162: Human TNFR1/CD120a/TNFRSF1A Protein with the C-His Tag

Source: The recombinant Human TNFR1/CD120a/TNFRSF1A Protein, (amino acids Leu30-Thr211) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human TNFR1 protein with the C-His tag at 0.5 ug/ml (100 ul/Well). Dose response curve for the recombinant Biotinylated Human TNF alpha protein with the C-His tag with the EC50 of 16.5 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP005161: Human TNFR1/CD120a/TNFRSF1A Protein with the C-hFc Tag

Source: The recombinant Human TNFR1/CD120a/TNFRSF1A Protein, (amino acids Leu30-Thr211) fused with a hFc tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human TNF alpha protein with the C-hFc tag at 1 ug/ml (100 ul/Well) on the plate. Dose response curve for the recombinant Human TNFR1 protein with the C-hFc tag with the EC50 of 3.8 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP003710: Cynomolgus TNFR1/CD120a/TNFRSF1A Protein with the C-His Tag

Source: The recombinant Cynomolgus TNFR1/CD120a/TNFRSF1A Protein, (amino acids Leu30-Thr211) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Cynomolgus TNFR1 protein with the C-His tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Biotinylated Human TNF alpha protein with the C-His tag with the EC50 of 17.2 ng/ml determined by ELISA (QC Test). The affinity constant of 0.23 nM as determined in SPR assay (Biacore T200).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

C009P: Trastuzumab Biosimilar, HER2/ErbB-2/c-neu Monoclonal Antibody

Recombinant Humanized IgG1 Monoclonal Antibody.
Specificity/Sensitivity: The monoclonal antibody trastuzumab biosimilar specifically binds to the human HER2 / ErbB-2 / c-neu.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by trastuzumab.

C002P: Cetuximab Biosimilar, Human EGFR Monoclonal Antibody

Recombinant Chimeric IgG1 Monoclonal Antibody.
Specificity/Sensitivity: The monoclonal antibody cetuximab biosimilar specifically binds to the human EGFR.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by cetuximab.

C010P: Rituximab Biosimilar, CD20 Monoclonal Antibody

Recombinant Humanized IgG1 Monoclonal Antibody.
Specificity/Sensitivity: The monoclonal antibody rituximab biosimilar specifically binds to the human TNF alpha.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by rituximab.

C075P: Etanercept Biosimilar

Recombinant protein composed of the soluble TNF receptor 2 fused with the Fc region of human immunoglobulin gamma 1 (hIgG1).
Specificity/Sensitivity: The etanercept biosimilar protein specifically binds to the human TNF alpha.
Applications: Functional assays, and those assays for studying biological pathways affected by etanercept.

C040P: Alemtuzumab Biosimilar, CD52 Monoclonal Antibody

Recombinant Humanized IgG1 Monoclonal Antibody.
Specificity/Sensitivity: The monoclonal antibody alemtuzumab biosimilar specifically binds to the human CD52, a protein present on the surface of mature lymphocytes.
Applications: ELISA, flow cytometry, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by alemtuzumab.