PA007380.m2b: In vivo Grade Recombinant Anti-mouse CTLA-4 Monoclonal Antibody, Mouse IgG2b Kappa (Clone: 9D9)

Recombinant Mouse IgG2b Monoclonal Antibody. 
Specificity/Sensitivity: The in vivo grade recombinant mouse monoclonal antibody (clone: 9D9) specifically binds to the mouse CTLA-4 protein.
Applications: ELISA, flow cytometry, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the mouse CTLA-4 protein.

BP004987: Biotinylated Human PD-1/PDCD1 Protein with the C-His-Avi Tag

Source: The recombinant Biotinylated Human PD-1/PDCD1 Protein, (amino acids Leu25-Gln167) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Biotinylated Human PD-1 protein with the C-His-Avi tag at 1 ug/ml (100 ul/Well) on streptavidin (5 ug/ml) precoated plate. Dose response curve for the recombinant Human PD-L1 protein with the C-hFc Tag with the EC50 of 23.5ng/ml determined by ELISA (QC Test). The affinity constant of 2.356 uM as determined in SPR assay (Biacore T200).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP005587: Biotinylated Human PD-1/PDCD1 Protein with the C-hFc-Avi Tag

Source: The recombinant Biotinylated Human PD-1/PDCD1 Protein, (amino acids Leu25-Gln167) fused with a hFc-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human PD-L1 protein with the C-hFc-Avi tag at 2 ug/ml (100 ul/Well). Dose response curve for the recombinant Biotinylated Human PD-1 protein with the C-hFc tag with the EC50 of 0.23 ug/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP003743: Biotinylated Mouse PD-1/PDCD1 Protein with the C-hFc Tag

Source: The recombinant Biotinylated Mouse PD-1/PDCD1 Protein, (amino acids Leu25-Gln167) fused with a hFc tag at the C-terminus, was produced in HEK 293 cells.
Activity: The affinity constant of 3.35 uM as determined in SPR assay (Biacore T200).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

PA005171: In Vivo Grade Recombinant Mouse IgG2c Isotype Control Antibody

The in vivo grade recombinant mouse IgG2c isotype control antibody was produced in mammalian cells.
Applications: an isotype-matched negative control for mouse IgG2c kappa antibodies used in ELISA, Western Blot (WB), Flow Cytometry (Flow), Immunoprecipitation (IP), Immunohistochemistry (Paraffin) (IHC (P)), Immunohistochemistry (Frozen) (IHC (F)), and in vivo animal model research.
Endotoxin Level: Less than 1 EU/mg of protein as determined by LAL method.

PA007141: In Vivo Grade Recombinant Mouse IgG2c-L234A L235A P329G Isotype Control Antibody

The in vivo grade recombinant mouse IgG2c-L234A L235A P329G (mIgG2c LALAPG, Fc silenced) isotype control antibody was produced in mammalian cells.
Applications: an isotype-matched negative control for mouse IgG2c LALAPG kappa antibodies used in ELISA, Western Blot (WB), Flow Cytometry (Flow), Immunoprecipitation (IP), Immunohistochemistry (Paraffin) (IHC (P)), Immunohistochemistry (Frozen) (IHC (F)), and in vivo animal model research.
Endotoxin Level: Less than 1 EU/mg of protein as determined by LAL method.

PA007144: In vivo Grade Recombinant Rat IgG2b Isotype Control Antibody

The in vivo grade recombinant rat IgG2b isotype control antibody was produced in mammalian cells.
Applications: an isotype-matched negative control for rat IgG2b kappa antibodies used in ELISA, Western Blot (WB), Flow Cytometry (Flow), Immunoprecipitation (IP), Immunohistochemistry (Paraffin) (IHC (P)), Immunohistochemistry (Frozen) (IHC (F)), and in vivo animal model research.
Endotoxin: Less than 1 EU/mg of protein as determined by LAL method.

PA007146: In Vivo Grade Recombinant Armenian Hamster IgG1 Isotype Control Antibody

The in vivo grade recombinant hamster IgG1 isotype control antibody was produced in mammalian cells.
Applications: an isotype-matched negative control for hamster IgG1 kappa antibodies used in ELISA, Western Blot (WB), Flow Cytometry (Flow), Immunoprecipitation (IP), Immunohistochemistry (Paraffin) (IHC (P)), Immunohistochemistry (Frozen) (IHC (F)), and in vivo animal model research.
Endotoxin: Less than 1 EU/mg of protein as determined by LAL method.

PA007148: In Vivo Grade Recombinant Syrian Hamster IgG1 Isotype Control Antibody

The in vivo grade recombinant hamster IgG1 isotype control antibody was produced in mammalian cells.
Applications: an isotype-matched negative control for hamster IgG1 kappa antibodies used in ELISA, Western Blot (WB), Flow Cytometry (Flow), Immunoprecipitation (IP), Immunohistochemistry (Paraffin) (IHC (P)), Immunohistochemistry (Frozen) (IHC (F)), and in vivo animal model research.
Endotoxin: Less than 1 EU/mg of protein as determined by LAL method.

PA008002.m2cLA: In Vivo Grade Recombinant Anti-mouse PD-1 / PD-L1 Bispecific Antibody, Mouse IgG2c LALAPG Kappa (Clone RMP1-14.1 / 10F.9G2.1)

The in vivo grade recombinant anti-mouse PD-1 / PD-L1 bispecific antibody (mouse IgG2c-LALAPG kappa) was produced in mammalian cells.
Applications: immunohistochemistry (IHC), Flow Cytometry (FC), and various in vitro and in vivo functional assays.
Endotoxin Level: Less than 1 EU/mg of protein as determined by LAL method.

PA008003.m2cLA: In Vivo Grade Recombinant Anti-mouse PD-L1 / PD-1 Bispecific Antibody, Mouse IgG2c LALAPG Kappa (Clone 10F.9G2.1 / RMP1-14.1)

The in vivo grade recombinant anti-mouse PD-L1 / PD-1 bispecific antibody (mouse IgG2c-LALAPG kappa) was produced in mammalian cells.
Applications: immunohistochemistry (IHC), Flow Cytometry (FC), and various in vitro and in vivo functional assays.
Endotoxin Level: Less than 1 EU/mg of protein as determined by LAL method.

BP002609-CF25: Recombinant Human Programmed Cell Death Protein 10 (PDCD10)

Source: E. coli-derived.
Purity: > 95% by SEC-HPLC and reducing SDS-PAGE.
Endotoxin: < 0.1 ng/ug (1 IEU/ug).

PA007163.m2cLA: In Vivo Grade Recombinant Anti-mouse PD-1 Mouse IgG2c-L234A L235A P329G (LALAPG) Kappa Monoclonal Antibody (Clone 29F.1A12.1)

The in vivo grade recombinant anti-mouse PD-1 monoclonal antibody (mouse IgG2c-LALAPG kappa) was produced in mammalian cells.
Applications: western blot (WB), immunohistochemistry (IHC), Flow Cytometry (FC), and various in vitro and in vivo functional assays.
Endotoxin Level: Less than 1 EU/mg of protein as determined by LAL method.

PA007163.r2a: In Vivo Grade Recombinant Anti-mouse PD-1 Rat IgG2a Kappa Monoclonal Antibody (Clone 29F.1A12.1)

The in vivo grade recombinant anti-mouse PD-1 monoclonal antibody (rat IgG2a kappa) was produced in mammalian cells.
Applications: western blot (WB), immunohistochemistry (IHC), Flow Cytometry (FC), and various in vitro and in vivo functional assays.
Endotoxin Level: Less than 1 EU/mg of protein as determined by LAL method.

PA007162.r2a: In Vivo Grade Recombinant Anti-mouse PD-1 Monoclonal Antibody (Clone RMP1-14.1), Rat IgG2a Kappa

The in vivo grade recombinant anti-mouse PD-1 / CD279 monoclonal antibody (rat IgG2a kappa) was produced in mammalian cells. Its affintiy to the mouse PD-1 protein is <2 nM.
Applications: immunohistochemistry (IHC), Flow Cytometry (FC), and various in vitro and in vivo functional assays.
Endotoxin Level: Less than 1 EU/mg of protein as determined by LAL method.

PA007162.m2cLA: In Vivo Grade Recombinant Anti-mouse PD-1 Monoclonal Antibody (Clone RMP1-14.1), Mouse IgG2c-L234A L235A P329G (LALAPG) Kappa

The in vivo grade recombinant anti-mouse PD-1 / CD279 monoclonal antibody (mouse IgG2c-LALAPG kappa) was produced in mammalian cells.
Applications: immunohistochemistry (IHC), Flow Cytometry (FC), and various in vitro and in vivo functional assays.
Endotoxin Level: Less than 1 EU/mg of protein as determined by LAL method.