PA007128: In Vivo Grade Recombinant Human IgG4-S228P Isotype Control Antibody (hIgG4 Isotype Control)

The recombinant human IgG4-S228P isotype control antibody (hIgG4 S228P isotype control) was produced in CHO cells.
Applications: an isotype-matched negative control for human IgG4 kappa antibodies used in ELISA, Western Blot (WB), Flow Cytometry (Flow), Immunoprecipitation (IP), Immunohistochemistry (Paraffin) (IHC (P)), Immunohistochemistry (Frozen) (IHC (F)), and in vivo animal model research.
Endotoxin Level: Less than 1 EU/mg of protein as determined by LAL method. Endotoxin ≤0.05 EU/mg for PA007128.05, in vivo grade recombinant human IgG4-S228P isotype control antibody, premium grade (endotoxin ≤0.05 EU/mg).

PA007131: In Vivo Grade Recombinant Human IgG4-S228P L235E P329G Isotype Control Antibody (hIgG4 SPLEPG Isotype Control Mutant)

The recombinant human IgG4-S228P L235E P329G isotype control antibody (hIgG4 SPLEPG isotype control mutant, Fc silenced) was produced in mammalian cells.
Applications: an isotype-matched negative control for human IgG4 SPLEPG kappa antibodies used in ELISA, Western Blot (WB), Flow Cytometry (Flow), Immunoprecipitation (IP), Immunohistochemistry (Paraffin) (IHC (P)), Immunohistochemistry (Frozen) (IHC (F)), and in vivo animal model research.
Endotoxin Level: Less than 1 EU/mg of protein as determined by LAL method.

PA007500.r2b: Recombinant Anti-mouse CD8b Monoclonal Antibody (Clone: YTS 156.7), Rat IgG2b Kappa

Recombinant Rat IgG2b Monoclonal Antibody.
Conjugation: Non-conjugated.
Specificity/Sensitivity: The recombinant YTS 156.7 antibody specifically binds to mouse CD8b protein.
Applications: Flow cytometry (FC), and Immunohistochemistry - Frozen (IHC-F).

PA007500.h1Fs: Recombinant Anti-mouse CD8b Monoclonal Antibody (Clone: YTS 156.7), Human IgG1 Fc Silent Kappa

Recombinant human IgG1 Monoclonal Antibody with Fc silent mutation.
Conjugation: Non-conjugated.
Specificity/Sensitivity: The recombinant YTS 156.7 antibody specifically binds to mouse CD8b protein.
Applications: Flow cytometry (FC), and Immunohistochemistry - Frozen (IHC-F).

PA007729.h1Fs-b: Biotinylated Recombinant Anti-mouse CD8b Monoclonal Antibody (Clone: YTS 156.7), Human IgG1 Fc Silent Kappa

Recombinant human IgG1 monoclonal antibody with site-directed biotinylation through the Avi tag at the C-terminus of the antibody heavy chain.
Conjugation: Biotin-conjugated.
Specificity/Sensitivity: The site-directed biotinylated recombinant YTS 156.7 antibody specifically binds to mouse CD8b protein.
Applications: Flow cytometry (FC) with various dye conjugation through streptavidin; conjugation to streptavidin agarose beads or streptavidin magnetic beads.

PA007490.m2a: Recombinant Anti-mouse CD28 Monoclonal Antibody (Clone: PV-1), Mouse IgG2a Kappa

Recombinant Mouse IgG2a Monoclonal Antibody.
Conjugation: Non-conjugated.
Specificity/Sensitivity: The recombinant PV-1 antibody specifically binds to mouse CD28.
Applications: Flow cytometry (FC), and Immunohistochemistry - Frozen (IHC-F).

PA007490.h1Fs: Recombinant Anti-mouse CD28 Monoclonal Antibody (Clone: PV-1), Human IgG1 Fc Silent Kappa

Recombinant human IgG1 Monoclonal Antibody with Fc silent mutation.
Conjugation: Non-conjugated.
Specificity/Sensitivity: The recombinant PV-1 antibody specifically binds to mouse CD28.
Applications: Flow cytometry (FC), and Immunohistochemistry - Frozen (IHC-F).

PA007720.h1Fs-b: Biotinylated Recombinant Anti-mouse CD28 Monoclonal Antibody (Clone: PV-1), Human IgG1 Fc Silent Kappa

Recombinant human IgG1 monoclonal antibody with site-directed biotinylation through the Avi tag at the C-terminus of the antibody heavy chain.
Conjugation: Biotin-conjugated.
Specificity/Sensitivity: The site-directed biotinylated recombinant PV-1 antibody specifically binds to mouse CD28.
Applications: Flow cytometry (FC) with various dye conjugation through streptavidin; conjugation to streptavidin agarose beads or streptavidin magnetic beads.

PA007413.m2a: Non-conjugated Recombinant Anti-human CD4 Monoclonal Antibody (Clone: OKT4A), Mouse IgG2a Kappa

Recombinant  mouse IgG2a Monoclonal Antibody. 
Conjugation: Non-conjugated.
Specificity/Sensitivity: The recombinant OKT4A antibody specifically binds to human and non-human primate CD4.
Applications: Flow cytometry (FC), and Immunohistochemistry - Frozen (IHC-F). 

PA007413.h1Fs: Non-conjugated Recombinant Anti-human CD4 Monoclonal Antibody (Clone: OKT4A), Human IgG1 Fc Silent Kappa

Recombinant  human IgG1 Monoclonal Antibody. 
Conjugation: Non-conjugated.
Specificity/Sensitivity: The recombinant OKT4A antibody specifically binds to human and non-human primate CD4.
Applications: Flow cytometry (FC), and Immunohistochemistry - Frozen (IHC-F).

PA007477.m1: In vivo Grade Recombinant Anti-Human CD28 Monoclonal Antibody, Mouse IgG1 Kappa (Clone: CD28.2)

The in vivo grade recombinant anti-human CD28 Mouse IgG1 Kappa monoclonal antibody was produced in mammalian cells. 
Specificity/Sensitivity: The in vivo grade recombinant mouse monoclonal antibody (clone: CD28.2) specifically binds to human CD28.
Applications: ELISA, flow cytometry, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the human CD28 protein.

PA007637.r2a: In Vivo Grade Recombinant Anti-mouse CD366 (TIM-3) Monoclonal Antibody (Clone: RMT3-23), Rat IgG2a Kappa

Recombinant Rat IgG2a Monoclonal Antibody.
Specificity/Sensitivity: The in vivo grade recombinant rat monoclonal antibody (clone: RMT3-23) specifically binds to mouse CD366 (TIM-3).
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the mouse CD366 (TIM-3) protein.

PA007561.r2a: In Vivo Grade Recombinant Anti-mouse CD62L (L-Selectin) Monoclonal Antibody (Clone: MEL-14), Rat IgG2a Kappa

Recombinant rat IgG2a Monoclonal Antibody.
Specificity/Sensitivity: The in vivo grade recombinant rat monoclonal antibody (clone: MEL-14) specifically binds to mouse CD62L (L-Selectin).
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the mouse CD62L (L-Selectin) protein.

PA007156.m2c: In vivo Grade Recombinant Anti-mouse CD25 Monoclonal Antibody (Clone PC61.5.3), Mouse IgG2c Kappa

The in vivo grade recombinant anti-mouse CD25 mouse IgG2c monoclonal antibody was produced in CHO cells.
Applications: immunoprecipitation (IP), immunohistochemistry (IHC), Flow Cytometry (FC), and various functional assays, such as in vivo depletion of CD25+CD4+ Treg cells, in vitro blocking of IL-2 binding to low- and high-affinity receptors, and growth inhibition of IL-2-dependent T-cell lines.
Endotoxin Level: Less than 1 EU/mg of protein as determined by LAL method.

PA007156.m2caf: In vivo Grade Recombinant Afucosylated Anti-mouse CD25 Monoclonal Antibody (Clone PC61.5.3), Mouse IgG2c Kappa

The in vivo grade recombinant afucosylated anti-mouse CD25 mouse IgG2c monoclonal antibody was produced in engineered CHO cells which produce afucosylated antibodies.
Applications: immunoprecipitation (IP), immunohistochemistry (IHC), Flow Cytometry (FC), and various functional assays, such as in vivo depletion of CD25+CD4+ Treg cells, in vitro blocking of IL-2 binding to low- and high-affinity receptors, and growth inhibition of IL-2-dependent T-cell lines.
Endotoxin Level: Less than 1 EU/mg of protein as determined by LAL method.

PA007550.r1: In Vivo Grade Recombinant Anti-mouse CD106 (VCAM-1) Monoclonal Antibody (Clone: M/K-2.7), Rat IgG1 Kappa

Recombinant Rat IgG1 Monoclonal Antibody.
Specificity/Sensitivity: The in vivo grade recombinant rat monoclonal antibody (clone: M/K-2.7) specifically binds to mouse CD106 (VCAM-1) .
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the mouse CD106 (VCAM-1) protein.

APIM050006: ADU-S100 (MIW815)

CAS No.: 1638750-95-4 (Sodium Salt), 1638241-89-0 (Free Acid)
Purity: >99.5% by HPLC (at 214 nm).
QC: HPLC, MS, ¹H-, ³¹P-NMRs,
Solubility: Water (>36.7mg/ml, >50 mM).