APIM050243: TAK-632
CAS No.: 1228591-30-7.
Purity: >99.5% (HPLC at 214 and 254 nm).
QC: HPLC-MS, 1HNMR.
Solubility: Soluble in DMSO.APIM050244: TAK-931 (SIMUROSERTIB)
CAS No.: 1330782-76-7.
Purity: >99.7% chem and optical purity (by achiral and chiral HPLCs).
QC: Achiral and Chiral HPLCs, 1H-NMR, and Quantitative Elemental Analysis Report.
Solubility: Refer to Certificate of Analysis.APIM050245: TANDUTINIB
CAS No.: 387867-13-2.
Purity: 99% (HPLC).
QC: 1HNMR, HPLC.
Solubility: Soluble in DMSO.APIM050246: TG100-115
CAS No.: 677297-51-7.
Purity: >99% (HPLC).
QC: LC/MS, 1HNMR.
Solubility: Soluble in DMSO.APIM050247: TG101348 (FEDRATINIB, SAR302503)
CAS No.: 936091-26-8.
Purity: >99% (HPLC at 220 and 254 nm).
QC: HPLC, 1HNMR, and Quantitative Elemental Analysis.
Solubility: Soluble in DMSO.APIM050248: TGX-221
CAS No.: 663619-89-4.
Purity: >99% (HPLC at 214 and 254 nm).
QC: LC/MS, 1HNMR.
Solubility: Soluble in DMSO and Alcohols.APIM050249: TORIN 2
CAS No.: 1223001-51-1.
Purity: 99.9% by HPLC at 214 and 254 nm.
QC: HPLC-MS, 1H-NMR, and Quantitative Elemental Analysis Report.
Solubility: Refer to Certificate of Analysis.APIM050250: ULIXERTINIB (BVD-523, VRT752271)
CAS No.: 869886-67-9.
Purity: 100% optical purity (Chiral HPLC), 99.5% chemical purity (HPLC at 214 and 254 nm).
QC: HPLC-MS, 1HNMR, Chiral HPLC and Quantitative Elemental Analysis.
Solubility: Soluble in DMSO.APIM050251: UPROSERTIB (GSK2141795)
CAS No.: 1047634-65-0 (free base) 1047635-80-2 (HCl salt).
Purity: 99.5% chem purity (HPLC at 214 and 254 nm), 100% optical purity (Chiral HPLC), [α]20D = +5.4 o (c 1.0, MeOH).
QC: HPLC-MS, 1HNMR, Chiral HPLC, and Quantitative Elemental Analysis Report.
Solubility: Soluble in DMSO.APIM050252: VANDETANIB
CAS No.: 443913-73-3.
Purity: >99% (HPLC).
QC: 1HNMR, HPLC.
Solubility: Soluble in DMSO.