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Background Information:
A Potent and specific PI3K p110β inhibitor.
Reference:
1. Hennessy, B.T., et al. Exploiting the PI3K/AKT pathway for cancer drug discovery. Nature Reviews Drug Discovery, 4, 988-1004 (2005).
2. Jackson, S.P., et al., PI 3-kinase p110β: A new target for antithrombotic therapy. Nature Med 11(5) 507-514 (2005).
APIM050248: TGX-221
CAS No.: 663619-89-4.
Molecular Formula: C21H24N4O2.
Molecular Weight: 364.44.
Purity: >99% (HPLC at 214 and 254 nm).
QC: LC/MS, 1HNMR.
Solubility: Soluble in DMSO and Alcohols.
Storage: Store at 0°C (short term), -20°C (long term), desiccated.
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