Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
| Catalog No. | Product Name | Size | List Price (US$) | Quantity |
|---|
Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Or leave a message with a formal purchase
order (PO) Or credit card.
Background Information:
TAK-632 is a potent and selective pan-RAF inhibitor targeting B-RAF V600E (IC?? = 2.4 nM), C-RAF (IC?? 1.4 nM) and VEGFR (IC?? = 160 nM), displaying significant cellular activity against mutated BRAF and mutated NRAS cancer cell lines.
Reference:
1. M.Okaniwa , et al., Discovery of a Selective Kinase Inhibitor (TAK-632) Targeting Pan-RAF Inhibition: Design, Synthesis, and Biological Evaluation of C-7-Substituted 1,3-Benzothiazole Derivatives, J. Med. Chem., 2013, 56 (16), pp 6478–6494.
APIM050243: TAK-632
CAS No.: 1228591-30-7.
Molecular Formula: C27H18F4N4O3S.
Molecular Weight: 554.5.
Purity: >99.5% (HPLC at 214 and 254 nm).
QC: HPLC-MS, 1HNMR.
Solubility: Soluble in DMSO.
Storage: Store at 0°C (short term), -20°C (long term), desiccated.
Copyright © 2009-2022 sydlabs.com. All rights reserved.
Use of this website means that you have read, understood, and accepted the Syd Labs Privacy Policy and Terms & Conditions.