BP000221-CYT-357: Recombinant Ovine Leptin Antagonist Quadruple Mutant
Source: E. Coli-derived.
ProSpec leptin qA is capable of inhibiting leptin-induced proliferation of BAF/3 cells stably transfected with the long form of ovine leptin receptor. It also inhibits various leptin effects in several in vitro bioassays.
Purity > 98.0% as determined by Gel filtration analysis and SDS-PAGE.BP000221-CYT-566: Recombinant Mouse Leptin Antagonist Triple Mutant Pegylated
Source: E. Coli-derived.
Purity > 99.0% as determined by Gel filtration analysis and SDS-PAGE.BP000221-CYT-567: Recombinant Rat Leptin Antagonist Triple Mutant Pegylated
Source: E. Coli-derived.
Purity > 99.0% as determined by Gel filtration analysis and SDS-PAGE.BP000221-CYT-702: Recombinant Human Leptin Antagonist Triple Mutant Pegylated
Source: E. Coli-derived.
Capable of inhibiting leptin-induced proliferation of BAF/3 cells stably transfected with the long form of human leptin receptor. Its in vitro activity is 6-8 fold lower than the non-pegylated antagonist but in vivo it has profound weight gain effect (as compared to the non-pegylated antagonist), resulting mainly from increased food intake. Its in vivo activity compared to that of PEG-MLA is 9-27 fold higher.
Purity > 98.0% by Gel filtration analysis and SDS-PAGE.BP000221-CYT-703: Recombinant Ovine Leptin Antagonist Triple Mutant Pegylated
Source: E. Coli-derived.
Purity > 95.0% as determined by Gel filtration analysis and SDS-PAGE.BP000221-CYT-530: Recombinant Pufferfish Leptin
Source: E. Coli-derived.
Biological active as evidenced by inducing proliferation of BAF/3 cells stably transfected with the long form of human leptin receptor. The affinity of human leptin receptors is considerably lower campared to mammalian leptins.
Purity > 99.0% by reducing SDS?PAGE and SEC-HPLC.BP000221-CYT-531: Recombinant Ovine Leptin, MTS tag
Source: E. Coli-derived.
Biological active as evidenced by inducing proliferation of BAF/3 cells stably transfected with the long form of human leptin receptor.
Purity > 98.0% by reducing SDS?PAGE and SEC-HPLC.BP000221-CYT-591: Recombinant Mouse Pegylated Leptin
Source: E. Coli-derived.
Pegylated mouse Leptin is capable of stimulatng proliferation of BAF/3 cells stably transfected with the long form of human leptin receptor. Pegylated mouse Leptin in vitro activity is only slightly lower than the non-pegylated antagonist but in vivo it has profound weight reducing effect (as compared to the non-pegylated leptin), resulting mainly from reduced food intake.
Purity > 99.0% by Gel-Filtration and SDS?PAGE.BP000221-CYT-683: Human Leptin
Source: E. Coli-derived.
Purity > 95.0% by RP-HPLC.