PA007527.r1: In Vivo Grade Recombinant Anti-mouse VEGFR-2 Monoclonal Antibody (Clone: DC101), Rat IgG1 Kappa
The in vivo grade recombinant anti-mouse VEGFR-2 rat IgG1 monoclonal antibody (clone of DC101) was produced in mammalian cells.
Applications: Western blot, immunoprecipitation (IP), Flow Cytometry (FC), and various in vitro and in vivo functional assays.C013P: Aflibercept Biosimilar
Recombinant protein composed of the binding domains of two human vascular endothelial growth factor (VEGF) receptors fused with the Fc region of human immunoglobulin gamma 1 (IgG1).
Specificity/Sensitivity: The aflibercept biosimilar protein specifically binds to the human VEGF.
Applications: Functional assays, and those assays for studying biological pathways affected by aflibercept.C005P: Ranibizumab Biosimilar, Human VEGF Monoclonal Antibody Fragment (Fab)
Recombinant Humanized Monoclonal Antibody Fragment (Fab) generated from the same parent mouse antibody as bevacizumab.
Specificity/Sensitivity: The research grade Fab protein ranibizumab specifically binds to the human VEGF-A.
Applications: Functional assay, neutralization.C061P: Ramucirumab Biosimilar, Human VEGFR2 Monoclonal Antibody
Recombinant Human IgG1 Monoclonal Antibody.
Specificity/Sensitivity: The monoclonal antibody ramucirumab biosimilar specifically binds to the human VEGFR2 (KDR).
Applications: ELISA, flow cytometry, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by ramucirumab.C001P: Bevacizumab Biosimilar, Human VEGF Monoclonal Antibody
Recombinant Humanized IgG1 Monoclonal Antibody generated from the same parent mouse antibody as ranibizumab.
Specificity/Sensitivity: The monoclonal antibody bevacizumab biosimilar specifically binds to the human VEGF-A.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by bevacizumab.C005: Lucentis Biosimilar Cell Line (E. coli)
The yield of Lucentis biosimilar from E.coli was above 36 mg/L in a 7.5 liter manufacturing.
C001: Avastin Biosimilar Stable Cell Line (CHO)
The yield of Avastin biosimilar from the CHO stable cell line was above 1.7 g/L in a 750 liter manufacturing.
APIM050203: MOTESANIB (FREE BASE)
CAS No.: 453562-69-1.
Purity: > 99% (HPLC).
QC: LC/MS, 1HNMR.
Solubility: Soluble in DMSO.APIM050204: MOTESANIB DIPHOSPHATE
CAS No.: 857876-30-3.
Purity: > 99% (HPLC).
QC: LC/MS, 1HNMR.
Solubility: Soluble in water.C013: Zaltrap / Eylea Biosimilar Stable Cell Line (CHO)
The yield of Zaltrap / Eylea biosimilar from the CHO stable cell line was above 2.1 g/L in a 3 liter manufacturing.