PA007168.m2a: In Vivo Grade Recombinant Anti-Mouse OX40 Mouse IgG2a Kappa Monoclonal Antibody

The in vivo grade recombinant anti-mouse OX40 mouse IgG2a monoclonal antibody (clone of OX86) was produced in mammalian cells.
Applications: ELISA, Western blot (WB), immunofluorescence (IF), Flow Cytometry (FC), and various in vitro and in vivo functional assays.

PA007168.r1: In Vivo Grade Recombinant Anti-Mouse OX40 Rat IgG1 Kappa Monoclonal Antibody

The in vivo grade recombinant anti-mouse OX40 rat IgG1 monoclonal antibody (clone of OX86) was produced in mammalian cells.
Applications: ELISA, Western blot (WB), immunofluorescence (IF), Flow Cytometry (FC), and various in vitro and in vivo functional assays.

PA007503.r1: Recombinant Anti-mouse OX40 Monoclonal Antibody (Clone: OX86), Rat IgG1 Kappa

Recombinant Rat IgG1 Monoclonal Antibody.
Conjugation: Non-conjugated.
Specificity/Sensitivity: The recombinant OX86 antibody specifically binds to mouse OX40 protein.
Applications: Flow cytometry (FC), and Immunohistochemistry - Frozen (IHC-F).

PA007503.h1Fs: Recombinant Anti-mouse OX40 Monoclonal Antibody (Clone: OX86), Human IgG1 Fc Silent Kappa

Recombinant human IgG1 Monoclonal Antibody with Fc silent mutation.
Conjugation: Non-conjugated.
Specificity/Sensitivity: The recombinant OX86 antibody specifically binds to mouse OX40 protein.
Applications: Flow cytometry (FC), and Immunohistochemistry - Frozen (IHC-F).

PA007732.h1Fs-b: Biotinylated Recombinant Anti-mouse OX40 Monoclonal Antibody (Clone: OX86), Human IgG1 Fc Silent Kappa

Recombinant human IgG1 monoclonal antibody with site-directed biotinylation through the Avi tag at the C-terminus of the antibody heavy chain. 
Conjugation: Biotin-conjugated.
Specificity/Sensitivity: The site-directed biotinylated recombinant OX86 antibody specifically binds to mouse OX40 protein.
Applications: Flow cytometry (FC) with various dye conjugation through streptavidin; conjugation to streptavidin agarose beads or streptavidin magnetic beads.

PA007274.r2a: In vivo Grade Recombinant Anti-mouse CD40 Monoclonal Antibody, Rat IgG2a Kappa (Clone: FGK4.5)

Recombinant rat IgG2a Monoclonal Antibody. 
Specificity/Sensitivity: The in vivo grade recombinant rat monoclonal antibody (clone: FGK4.5) specifically binds to the mouse CD40 protein.
Applications: ELISA, flow cytometry, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the mouse CD40 protein.

PA007274.m2a: In vivo Grade Recombinant Anti-mouse CD40 Monoclonal Antibody, Mouse IgG2a Kappa (Clone: FGK4.5)

Recombinant mouse IgG2a Monoclonal Antibody. 
Specificity/Sensitivity: The in vivo grade recombinant mouse monoclonal antibody (clone: FGK4.5) specifically binds to the mouse CD40 protein.
Applications: ELISA, flow cytometry, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the mouse CD40 protein.

BP000106-CYT-598: Recombinant Human B-Cell Maturation Antigen

Source: E. coli-derived.
Purity > 98%, by SDS-PAGE and RP-HPLC.

PA007502.r2a: Recombinant Anti-mouse GITR Monoclonal Antibody (Clone: DTA-1), Rat IgG2b Lambda

Recombinant Rat IgG2b Monoclonal Antibody.
Conjugation: Non-conjugated.
Specificity/Sensitivity: The recombinant DTA-1 antibody specifically binds to mouse GITR protein.
Applications: Flow cytometry (FC), and Immunohistochemistry - Frozen (IHC-F).

PA007502.h1Fs: Recombinant Anti-mouse GITR Monoclonal Antibody (Clone: DTA-1), Human IgG1 Fc Silent Kappa

Recombinant human IgG1 Monoclonal Antibody with Fc silent mutation.
Conjugation: Non-conjugated.
Specificity/Sensitivity: The recombinant DTA-1 antibody specifically binds to mouse GITR protein.
Applications: Flow cytometry (FC), and Immunohistochemistry - Frozen (IHC-F).

PA007731.h1Fs-b: Biotinylated Recombinant Anti-mouse GITR Monoclonal Antibody (Clone: DTA-1), Human IgG1 Fc Silent Kappa

Recombinant human IgG1 monoclonal antibody with site-directed biotinylation through the Avi tag at the C-terminus of the antibody heavy chain.
Conjugation: Biotin-conjugated.
Specificity/Sensitivity: The site-directed biotinylated recombinant DTA-1 antibody specifically binds to mouse GITR protein.
Applications: Flow cytometry (FC) with various dye conjugation through streptavidin; conjugation to streptavidin agarose beads or streptavidin magnetic beads.

BP000125-CYT-422: Recombinant Human Tumor Necrosis Factor Receptor (TNFR)

Source: CHO-derived.
A dimeric, glycosylated, polypeptide chain consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1. The Fc component of TNFR contains the CH2 domain, the CH3 domain and hinge region, but not the CH1 domain of IgG1.
Potency is determined by its ability to neutralize TNF-alpha mediated growth inhibition of A375 cells, corresponding to a Specific Activity of 17,000,000 IU/mg.
Purity > 98%, by SDS-PAGE and RP-HPLC.

BP000227-CYT-266: Recombinant Human Osteoprotegerin/Fc Chimera

Source: Pichia Pastoris-derived.
Contains 412 amino acid residues, including 180 residues from mature OPG (a.a 22-201) and 232 residues from the Fc protein of human IgG1, and has a calculated molecular mass of 46.5 kDa.
Determined by its ability to neutralize the stimulation of U937 cells treated with 10 ug/ml of soluble RANKL (sRANKL) corresponding to a Specific Activity of 100,000 IU/mg.
Purity > 90%, by SDS-PAGE and RP-HPLC.

BP000051-GD14: Recombinant Human OPG-Fc Fusion Protein

Source: HEK 293-derived.
The Osteoprotegerin / OPG / TNFRSF11B / OCIF / OBF activity is calculated by its ability to inhibit TRAIL-mediated cytotoxicity using L929 mouse fibrosarcoma cells treated with TRAIL. The ED50 for this effect is typically 5 ng/ml.
Endotoxin: < 5.0 EU per 1 ug of the protein by the LAL method.
Purity: > 90% by SDS-PAGE and RP-HPLC.

BP000227-CYT-290: Recombinant Human Osteoprotegerin, His Tag

Source: E. coli-derived.
A single, non-glycosylated, polypeptide chain containing amino acids 201-401 and having a molecular mass of 31 kDa which includes a 4 kDa His tag.
Purity > 80%, by SDS-PAGE and RP-HPLC.
Applications: Positive control for Western blot; Antibody production; Protein assay.