PA007541.m1: In Vivo Grade Recombinant Anti-mouse TCR gamma/delta Monoclonal Antibody (Clone:  UC7-13D5), Mouse IgG1 Kappa

Recombinant mouse IgG1 Monoclonal Antibody.
Specificity/Sensitivity: The in vivo grade recombinant mouse monoclonal antibody (clone: UC7-13D5) specifically binds to mouse TCR gamma/delta.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the mouse TCR gamma/delta protein.

PA007541.hs: In Vivo Grade Recombinant Anti-mouse TCR gamma/delta Monoclonal Antibody (Clone:  UC7-13D5), Armenian Hamster IgG Kappa

Recombinant Hamster IgG Monoclonal Antibody.
Specificity/Sensitivity: The in vivo grade recombinant hamster monoclonal antibody (clone: UC7-13D5) specifically binds to mouse TCR gamma/delta.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the mouse TCR gamma/delta protein.

C038P: Ustekinumab Biosimilar, IL-12 / IL-23 Monoclonal Antibody

Recombinant Humanized IgG1 Monoclonal Antibody.
Specificity/Sensitivity: The in vivo grade ustekinumab biosimilar specifically binds to the human interleukin-12 (IL-12) and interleukin-23 (IL-23).
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by ustekinumab.

C041P: Briakinumab Biosimilar, IL-12 / IL-23 Monoclonal Antibody

Recombinant Humanized IgG1 Monoclonal Antibody.
Specificity/Sensitivity: The in vivo grade briakinumab biosimilar specifically binds to the human interleukin-12 (IL-12) and interleukin-23 (IL-23).
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by briakinumab.

C032P: Tocilizumab Biosimilar, Anti-Human IL-6R Monoclonal Antibody

Recombinant Humanized IgG1 Monoclonal Antibody.
Specificity/Sensitivity: The in vivo grade tocilizumab biosimilar specifically binds to the human interleukin-6 receptor (IL-6R).
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by tocilizumab.

BP000140-CYT-250: Recombinant Human Interleukin-17A (IL-17A) Protein

Source: E. coli-derived.
The ED50 as determined by the dose-dependent induction of IL-6 in Hs68 cell line was found to be approximately 2 ug/ml corresponding to a Specific Activity of 500,000 IU/mg.
Purity: > 95% by SDS-PAGE.

C034P: Secukinumab Biosimilar, Human IL17A Monoclonal Antibody

Recombinant fully human IgG1 monoclonal antibody.
Specificity/Sensitivity: The monoclonal antibody Secukinumab biosimilar specifically binds to the human IL17A.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by Secukinumab.

BP005475: Cynomolgus IL-17A/CTLA-8 Protein with the C-His-Avi Tag

Source: The recombinant Cynomolgus IL-17A/CTLA-8 Protein, (amino acids Gly24-Ala155) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Cynomolgus IL-17A protein with the C-His-Avi tag at 2 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Anti-IL-17A Antibody protein with the C-hFc tag with the EC50 of 4.4 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP005194: Human IL-17A/CTLA-8 Protein with the C-His Tag

Source: The recombinant Human IL-17A/CTLA-8 Protein, (amino acids Gly24-Ala155) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human IL-17A protein with the C-His tag at 2 ug/ml (100 ul/Well) on the plate. Dose response curve for the recombinant Human IL-17Rc protein with the C-hFc tag with the EC50 of 33.8 ng/ml determined by ELISA (Routine Test). The affinity constant of 1.57 nM as determined in SPR assay (Biacore T200).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP005195: Biotinylated Human IL-17A/CTLA-8 Protein with the C-His-Avi Tag

Source: The recombinant Biotinylated Human IL-17A/CTLA-8 Protein, (amino acids Gly24-Ala155) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Biotinylated Human IL-17A protein with the C-His-Avi tag at 2 ug/ml (100 ul/well) on the streptavidin precoated plate (5 ug/ml). Dose response curve for the recombinant Human IL-17R alpha protein with the C-hFc tag with the EC50 of 18.2 ng/ml determined by ELISA (QC Test). The affinity constant of 2.18 nM as determined in SPR assay (Biacore T200).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP005476: Mouse IL-17A/CTLA-8 Protein with the C-His-Avi Tag

Source: The recombinant Mouse IL-17A/CTLA-8 Protein, (amino acids Ala26-Ala158) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Mouse IL-17A protein with the C-His-Avi tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Mouse IL-17RA protein with the C-hFc tag with the EC50 of 122.6 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.