BP005195: Biotinylated Human IL-17A/CTLA-8 Protein with the C-His-Avi Tag
Source: The recombinant Biotinylated Human IL-17A/CTLA-8 Protein, (amino acids Gly24-Ala155) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Biotinylated Human IL-17A protein with the C-His-Avi tag at 2 ug/ml (100 ul/well) on the streptavidin precoated plate (5 ug/ml). Dose response curve for the recombinant Human IL-17R alpha protein with the C-hFc tag with the EC50 of 18.2 ng/ml determined by ELISA (QC Test). The affinity constant of 2.18 nM as determined in SPR assay (Biacore T200).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.BP005192: Biotinylated Mouse IL-17A/CTLA-8 Protein with the C-His-Avi Tag
Source: The recombinant Biotinylated Mouse IL-17A/CTLA-8 Protein, (amino acids Ala26-Ala158) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Mouse IL-17R alpha protein with the C-His-Avi tag at 2 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Biotinylated Mouse IL-17A protein with the C-His tag with the EC50 of 28.3 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.C041P: Briakinumab Biosimilar, IL-12 / IL-23 Monoclonal Antibody
Recombinant Humanized IgG1 Monoclonal Antibody.
Specificity/Sensitivity: The in vivo grade briakinumab biosimilar specifically binds to the human interleukin-12 (IL-12) and interleukin-23 (IL-23).
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by briakinumab.BP005475: Cynomolgus IL-17A/CTLA-8 Protein with the C-His-Avi Tag
Source: The recombinant Cynomolgus IL-17A/CTLA-8 Protein, (amino acids Gly24-Ala155) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Cynomolgus IL-17A protein with the C-His-Avi tag at 2 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Anti-IL-17A Antibody protein with the C-hFc tag with the EC50 of 4.4 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.BP005194: Human IL-17A/CTLA-8 Protein with the C-His Tag
Source: The recombinant Human IL-17A/CTLA-8 Protein, (amino acids Gly24-Ala155) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human IL-17A protein with the C-His tag at 2 ug/ml (100 ul/Well) on the plate. Dose response curve for the recombinant Human IL-17Rc protein with the C-hFc tag with the EC50 of 33.8 ng/ml determined by ELISA (Routine Test). The affinity constant of 1.57 nM as determined in SPR assay (Biacore T200).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.BP000139-CYT-623: Recombinant Human IL-17 A/F Heterodimer
Source: E. coli-derived.
Purity > 98%, by SDS-PAGE.BP000139-CYT-640: Recombinant Mouse IL-17 A/F Heterodimer
Source: E. coli-derived.
Purity > 97%, by SDS-PAGE.BP000139-CYT-677: Recombinant Rat IL-17 A/F Heterodimer
Source: E. coli-derived.
Purity > 97%, by SDS-PAGE.BP000140-C021: Recombinant Human Interleukin-17A (IL-17A) Protein
Source: E. coli-derived.
The ED50 as determined by the dose-dependent induction of IL-6 in primary human foreskin fibroblasts was found to be approximately 2 ug/ml, corresponding to a Specific Activity of 5 x 105 IU/mg.
Purity: > 95% by RP-HPLC and reducing SDS-PAGE.
Endotoxin: < 0.1 ng/ug (1 IEU/ug).BP000140-CYT-102: Recombinant Human Interleukin-17A (IL-17A), HEK Protein
Source: HEK-derived.
The specific activity was determined by the dose-dependent induction of IL-6 secretion from NDHF Adult fibroblasts and is typically 5-25 ug/ml.
Purity: > 95% as obsereved by SDS-PAGE.