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Home > Antibodies > Anti-Mouse Antibodies (In Vivo) > Anti-Mouse TCR gamma/delta Monoclonal Antibodies

Anti-Mouse TCR gamma/delta Monoclonal Antibodies

TCR gamma, TCRG, TCR delta, TCRD, TCRDV1

Catalog No. Product Name Size List Price (US$) Quantity
PA007541.m1 In Vivo Grade Recombinant Anti-mouse TCR gamma/delta Monoclonal Antibody (Clone: UC7-13D5), Mouse IgG1 Kappa 1 mg 150.00
PA007541.m1 In Vivo Grade Recombinant Anti-mouse TCR gamma/delta Monoclonal Antibody (Clone: UC7-13D5), Mouse IgG1 Kappa 5 mg 350.00
PA007541.m1 In Vivo Grade Recombinant Anti-mouse TCR gamma/delta Monoclonal Antibody (Clone: UC7-13D5), Mouse IgG1 Kappa 25 mg 900.00
PA007541.hs In Vivo Grade Recombinant Anti-mouse TCR gamma/delta Monoclonal Antibody (Clone: UC7-13D5), Armenian Hamster IgG Kappa 1 mg 150.00
PA007541.hs In Vivo Grade Recombinant Anti-mouse TCR gamma/delta Monoclonal Antibody (Clone: UC7-13D5), Armenian Hamster IgG Kappa 5 mg 350.00
PA007541.hs In Vivo Grade Recombinant Anti-mouse TCR gamma/delta Monoclonal Antibody (Clone: UC7-13D5), Armenian Hamster IgG Kappa 25 mg 900.00
Description

PA007541.m1: In Vivo Grade Recombinant Anti-mouse TCR gamma/delta Monoclonal Antibody (Clone:  UC7-13D5), Mouse IgG1 Kappa

Recombinant mouse IgG1 Monoclonal Antibody.
Clone: UC7-13D5.
Isotype: Mouse IgG1 kappa.
Source: The anti-mouse TCR gamma/delta monoclonal antibody (clone: UC7-13D5) was produced in mammalian cells.
Specificity/Sensitivity: The in vivo grade recombinant mouse monoclonal antibody (clone: UC7-13D5) specifically binds to mouse TCR gamma/delta.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the mouse TCR gamma/delta protein.
Form of Antibody: 0.2 uM filtered solution, pH 7.4, no stabilizers or preservatives.
Endotoxin: < 1 EU per 1 mg of the protein by the LAL method.
Purity: >95% by SDS-PAGE under reducing conditions and HPLC.

PA007541.hs: In Vivo Grade Recombinant Anti-mouse TCR gamma/delta Monoclonal Antibody (Clone:  UC7-13D5), Armenian Hamster IgG Kappa

Recombinant Hamster IgG Monoclonal Antibody.
Clone: UC7-13D5.
Isotype: Armenian Hamster IgG Kappa.
Source: The anti-mouse TCR gamma/delta monoclonal antibody (clone: UC7-13D5) was produced in mammalian cells.
Specificity/Sensitivity: The in vivo grade recombinant hamster monoclonal antibody (clone: UC7-13D5) specifically binds to mouse TCR gamma/delta.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the mouse TCR gamma/delta protein.
Form of Antibody: 0.2 uM filtered solution, pH 7.4, no stabilizers or preservatives.
Endotoxin: < 1 EU per 1 mg of the protein by the LAL method.
Purity: >95% by SDS-PAGE under reducing conditions and HPLC.

Shipping: The in vivo grade recombinant anti-mouse TCR gamma/delta monoclonal antibody of clone UC7-13D5 is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month from date of receipt, 2 to 8°C as supplied.

References of Anti-mouse TCR γ/δ Monoclonal Antibody (Clone: UC7-13D5)

Benevides, L., et al. Cancer Res. 2015 Sep 15;75(18):3788-99. PMID: 26208902
We found that CD3+CD4+, CD3+CD8+, and CD3+γδ+ T cells produced IL17A and IFN-γ at all assessed points. ...In particular, we observed an increase in the number of IL17A-producing CD3+CD4+ and TCRγδ+ T cells at 25 and 35 dpi. ...For T-cell analysis, antibodies to the following mouse proteins were obtained: CD3 (145-2C11), CD4 (RM4-5), CD8 (53-6.7), TCR γδ (UC7-13D5), IL17A (TC11-18H10), and IFN-γ (XMG1.2).
(Tags: anti-mouse TCR gamma/delta UC7-13D5; anti-mouse TCR gamma/delta UC7-13D5 antibody)
Gillard, G. O., et al. PLoS Pathog. 2011 Aug;7(8):e1002141. PMID: 21829360
Ten days prior to a secondary vaccinia virus challenge we began administering isotype control antibodies or a cocktail of T cell-depleting monoclonal antibodies (clones GK1.5 (αCD4), H57-597 (αTCRαβ), and UC7-13D5 (αTCRγδ) ip) to groups of naïve and primed animals. ...The efficiency of T cell depletion was monitored by flow cytometric analysis of peripheral blood stained with a panel of monoclonal antibodies, including antibodies specific for CD3, TCRαβ, TCRγδ, and NK1.1. ...Very few of those cells that fall within the CD3+ gate in the depleted mice showed staining for TCRαβ, TCRγδ, or CD8α.
(Tags: anti-mouse TCR gamma/delta UC7-13D5 in vivo; anti-mouse TCR gamma/delta UC7-13D5 in animal model)
Skyberg, J. A., et al. PLoS One. 2011 Jul;6(7):e21978. PMID: 21765931
Third panel from top, cells were gated on γδ T cells (CD3+/TCRγδ+) and assayed for IFN-γ production. ...γδ T cells were found to be the major producer of IL-17 during infection and were also found to produce IFN-γ. ...Neutralization of γδ T cells enhanced the susceptibility of both wt and IL-17R-/- γδ-/- mice, and IL-17 receptor deficiency did not impact splenomegaly, nor tissue colonization by B. abortus. ...Deficiency of either IFN-γ or γδ T cells enhanced susceptibility to colonization by ~10-fold at one-week post-infection.
(Tags: anti-mouse TCR gamma/delta UC7-13D5 mAb in animal model; anti-mouse TCR gamma/delta UC7-13D5 in cancer research)
For more technical references or data sheets regarding the Anti-mouse TCR gamma/delta Monoclonal Antibody (Clone: UC7-13D5) formats, please contact our scientific support team at message@sydlabs.com.
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