PA007394.r2a: In vivo Grade Recombinant Anti-mouse CD115 Monoclonal Antibody, Rat IgG2a Kappa (Clone: AFS98)

The in vivo grade recombinant anti-mouse CD115 rat IgG2a monoclonal antibody was produced in mammalian cells. 
Specificity/Sensitivity: The in vivo grade recombinant rat monoclonal antibody (clone: AFS98) specifically binds to mouse CD115.
Applications: ELISA, flow cytometry, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the mouse CD115 protein.

PA007484.r2a: Recombinant Anti-mouse CD115 Monoclonal Antibody (Clone: AFS98), Rat IgG2a Kappa

Recombinant rat IgG2a Monoclonal Antibody.
Conjugation: Non-conjugated.
Specificity/Sensitivity: The recombinant AFS98 antibody specifically binds to mouse CD115.
Applications: Flow cytometry (FC), and Immunohistochemistry - Frozen (IHC-F).

PA007484.h1Fs: Recombinant Anti-mouse CD115 Monoclonal Antibody (Clone: AFS98), Human IgG1 Fc Silent Kappa

Recombinant human IgG1 Monoclonal Antibody with Fc silent mutation.
Conjugation: Non-conjugated.
Specificity/Sensitivity: The recombinant AFS98 antibody specifically binds to mouse CD115.
Applications: Flow cytometry (FC), and Immunohistochemistry - Frozen (IHC-F).

PA007716.h1Fs-b: Biotinylated Recombinant Anti-mouse CD115 Monoclonal Antibody (Clone: AFS98), Human IgG1 Fc Silent Kappa

Recombinant human IgG1 monoclonal antibody with site-directed biotinylation through the Avi tag at the C-terminus of the antibody heavy chain.
Conjugation: Biotin-conjugated.
Specificity/Sensitivity: The site-directed biotinylated recombinant AFS98 antibody specifically binds to mouse CD115.
Applications:  Flow cytometry (FC) with various dye conjugation through streptavidin; conjugation to streptavidin agarose beads or streptavidin magnetic beads.

BP005774: Biotinylated Human M-CSF R/CSF1R/CD115 Protein with the C-His-Avi Tag

Source: The recombinant Biotinylated Human M-CSF R/CSF1R/CD115 Protein, (amino acids Ile20-Glu512) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Anti-CSF R Antibody protein with the C-His-Avi tag at 0.5 ug/ml (100 ul/Well) on the plate. Dose response curve for the recombinant Biotinylated Human M-CSF R protein with the C-His tag with the EC50 of 27.7 ng/ml determined by ELISA (QC Test). The affinity constant of 0.81 uM as determined in SPR assay (Biacore T200).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP005053: Cynomolgus M-CSF R/CSF1R/CD115 Protein with the C-His Tag

Source: The recombinant Cynomolgus M-CSF R/CSF1R/CD115 Protein, (amino acids Ile99-Pro596) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Cynomolgus M-CSF R protein with the C-His tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Anti-M-CSF R Antibody protein with the C-hFc tag with the EC50 of 17.6 ng/ml determined by ELISA (QC Test). The affinity constant of 0.889 uM as determined in SPR assay (Biacore T200).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP003084: Recombinant Human M-CSF R / CSF1R / CD115 Protein

Source: mammalian cells.
Purity: > 95% by Bis-Tris PAGE and HPLC.

BP003280: Human M-CSF R/CSF1R/CD115 Protein with No Tag

Source: The recombinant Human M-CSF R/CSF1R/CD115 Protein, (amino acids Ile20-Glu512) fused with No Tag, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human M-CSF R protein with No tag at 0.5 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Anti-M-CSF R Antibody, hFc tag with the EC50 of 7.1 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP005052: Human M-CSF R/CSF1R/CD115 Protein with the C-hFc Tag

Source: The recombinant Human M-CSF R/CSF1R/CD115 Protein, (amino acids Ile20-Glu512) fused with a hFc tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human M-CSF protein with the C-hFc tag at 0.5 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Human M-CSF R protein with the C-hFc tag with the EC50 of 26.3 ng/ml determined by ELISA (QC Test). The affinity constant of 0.24 nM as determined in SPR assay (Biacore T200).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP005506: Human M-CSF R/CSF1R/CD115 Protein with the C-His-Avi Tag

Source: The recombinant Human M-CSF R/CSF1R/CD115 Protein, (amino acids Ile20-Glu512) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human M-CSF R protein with the C-His-Avi tag at 1 ug/ml (100 ul/Well). Dose response curve for the recombinant Anti-M-CSF R Antibody protein with the C-hFc tag with the EC50 of 6.0 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP004603: Mouse M-CSF R/CSF1R/CD115 Protein with the C-His Tag

Source: The recombinant Mouse M-CSF R/CSF1R/CD115 Protein, (amino acids Ala20-Ser511) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Activity: The affinity constant of 1.70 nM as determined in SPR assay (Biacore T200).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

PA007143: In Vivo Grade Recombinant Rat IgG2a Isotype Control Antibody

The in vivo grade recombinant rat IgG2a isotype control antibody was produced in mammalian cells.
Applications: an isotype-matched negative control for rat IgG2a kappa antibodies used in ELISA, Western Blot (WB), Flow Cytometry (Flow), Immunoprecipitation (IP), Immunohistochemistry (Paraffin) (IHC (P)), Immunohistochemistry (Frozen) (IHC (F)), and in vivo animal model research.
Endotoxin: Less than 1 EU/mg of protein as determined by LAL method.