BP003660: Human CCR8 Protein with the C-hFc Tag
Source: The recombinant Human CCR8 Protein, (amino acids Met1-Lys35) fused with a hFc tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human-CCR8 protein with the C-hFc tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Biotinylated Anti-CCR8 Antibody protein with the C-hFc tag with the EC50 of 29.6 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.BP003634: Human CCR8 Protein with the C-mFc Tag
Source: The recombinant Human CCR8 Protein, (amino acids Met1-Lys35) fused with a mFc tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human CCR8 protein with the C-mFc tag at 0.5 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Anti-CCR8 Antibody protein with the C-hFc tag with the EC50 of 11.1 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.BP003158: Human CCR7 (nanodisc) Protein with the C-His Tag
Source: The recombinant Human CCR7 (nanodisc) Protein, (amino acids Met1-Pro378) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human CCR7 (Nanodisc) protein with the C-His tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Anti-CCR7 Antibody protein with the C-hFc tag with the EC50 of 0.21 ug/ml determined by ELISA (QC Test). The affinity constant of 4.11 nM as determined in SPR assay (Biacore T200).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.BP004739: Human CCR2b Protein-VLP
Source: The recombinant Human CCR2b Protein-VLP, (amino acids Met1-Leu360), was produced in HEK 293 cells.
Activity: Immobilized recombinant Human CCR2b VLP at 5 ug/ml (100 ul/Well) on the plate. Dose response curve for the recombinant Anti-CCR2b Antibody, hFc tag with the EC50 of 0.11 ug/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.BP003482: Cynomolgus CCR8 Protein with the C-mFc Tag
Source: The recombinant Cynomolgus CCR8 Protein, (amino acids Met1-Lys35) fused with a mFc tag at the C-terminus, was produced in HEK 293 cells.
Activity: The affinity constant of 0.27 uM as determined in SPR assay (Biacore T200).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.BP004738: Biotinylated Human CCR2b Protein-VLP
Source: The recombinant Biotinylated Human CCR2b Protein-VLP, (amino acids Met1-Leu360) , was produced in HEK 293 cells.
Activity: The affinity constant of 5.24 nM as determined in SPR assay (Biacore T200).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.C053P: Mogamulizumab Biosimilar, CCR4 Monoclonal Antibody
Recombinant Humanized IgG1 Monoclonal Antibody.
Specificity/Sensitivity: The in vivo grade mogamulizumab biosimilar specifically binds to the human CC chemokine receptor 4 (CCR4).
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by mogamulizumab.BP001544-PRO-908: Recombinant Mouse CCR4-NOT Transcription Complex, Subunit 7 (CNOT7) Protein
Source: E. coli-derived.
Purity: > 80.0% as determined by SDS-PAGE.BP000306-CHM-240: Recombinant Human TARC (CCL17)
Source: E. coli-derived.
A single,non-glycosylated, polypeptide chain containing 71 amino acids and having a molecular mass of 8 kDa.
Determined by its ability to chemoattract human T-Lymphocytes using a concentration range of 1.0-10.0 ug/ml corresponding to a Specific Activity of 10,000-100,000 IU/mg.
Purity > 97%, by SDS-PAGE and RP-HPLC.BP000306-CHM-270: Recombinant Mouse TARC (CCL17)
Source: E. coli-derived.
A non-glycosylated, Polypeptide chain containing 70 amino acids and having a molecular mass of 7.9 kDa.
Fully biologically active when compared to standard. The ED50 as determined by its ability to chemoattract BaF3 mouse pro-B cells transfected with human CCR4 is typically 2-10 ug/ml.
Purity > 97%, by SDS-PAGE and RP-HPLC.BP000306-CHM-359: Recombinant Human TARC (CCL17), His Tag
Source: E. coli-derived.
A non-glycosylated, Polypeptide chain containing 92 amino acids (24-94 a.a.) and having a molecular mass of 10.3 kDa.
Purity > 95%, by SDS-PAGE.