Syd Labs has successfully developed human and monkey monoclonal antibodies using antigen specific single B cell-based antibody generation technologies. After detection and isolation of antigen specific memory B cells by flow cytometry-based single B cell sorting, the antibody variable regions (VH and VL) from single or clonal B cells are cloned and sequenced. Recombinant rabbit monoclonal antibodies are produced, purified, and tested for various applications, such as drug development and diagnostics.
Fast turnaround: 8-10 weeks once the polyclonal sera, PBMC, and antigen is available.Custom Ilama and alpaca monoclonal antibody development (VHH, sdAb or nanobody) by Ilama or alpaca immunization and phage display screening.
Production of camel, Ilama or alpaca VHH in E.coli or VHH-Fc in HEK 293 cells.
Fast turnaround: 4-6 months once the antigen is available.