APIM050506: 2'-OMe-Bz-C-CE-Phosphoramidite
CAS No.: 199593-09-4.
Molecular Formula: C47H54N5O9P.
Molecular Weight: 863.94.
Purity: (31P NMR) ≥99.0%; (RP-HPLC) ≥99.0%.
Impurity profile: (HPLC) any single critical impurity ≤ 0.15%; total critical impurities ≤ 0.3%; total impurities ≤ 1.0%.
Assay: (HPLC) 98.0%~102.0%.APIM050505: 2'-OMe-iBu-G-CE-Phosphoramidite
CAS No.: 150780-67-9.
Molecular Formula: C45H56N7O9P.
Molecular Weight: 869.94.
Purity: (31P NMR) ≥99.0%; (RP-HPLC) ≥99.0%.
Impurity profile: (HPLC) any single critical impurity ≤ 0.15%; total critical impurities ≤ 0.3%; total impurities ≤ 1.0%.
Assay: (HPLC) 98.0%~102.0%.APIM050504: 2'-OMe-Bz-A-CE-Phosphoramidite
CAS No.: 110782-31-5.
Molecular Formula: C48H54N7O8P.
Molecular Weight: 887.96.
Purity: (31P NMR) ≥99.0%; (RP-HPLC) ≥99.0%.
Impurity profile: (HPLC) any single critical impurity ≤ 0.15%; total critical impurities ≤ 0.3%; total impurities ≤ 1.0%.
Assay: (HPLC) 98.0%~102.0%.- nucleophosmin
- 10
- C. et al. “Abstract P5-04-07: GDC-9545: A novel ER antagonist and clinical candidate that combines desirable mechanistic and pre-clinical DMPK attributes”
- and inhibits MAPK pathway signaling. BI-3406 (BI3406) binds to the catalytic domain of SOS1
- 98 nM (BRD3 BD2)
- highly selective against other CDKs (>60 fold).
CAS No.: 2416874-75-2
IUPAC/Chemical Name: (R)-1-cyanobutan-2-yl ((S)-1-(3-(3-(3-methoxy-4-(oxazol-5-yl)phenyl)ureido)phenyl)ethyl)carbamate
Molecular Formula: C16H25N5•2HCl
Molecular Weight: 360.3
Purity: >99% pure by Achiral and Chiral HPLCs
QC: Achiral and Chiral HPLCs""""""" - 2-a]pyridin-3-yl]sulfonyl]-1H-pyrazolo[4