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Conditions of optimal 2'-OMe-iBu-G-CE-Phosphoramidite performance should be determined experimentally by the investigator. Its precursors, 2'-OMe-G (CAS # 2140-71-8) and N2-iBu-2'-OMe-5'-O-DMT-G (CAS # 114745-26-5), are available.
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APIM050505: 2'-OMe-iBu-G-CE-Phosphoramidite
CAS No.: 150780-67-9.
Molecular Formula: C45H56N7O9P.
Molecular Weight: 869.94.
Appearance: (visual inspection) white to off-white powder.
Identity: (molecular weight by MS) conforms to structure molecular weight; (1H NMR) conforms to structure.
Purity: (31P NMR) ≥99.0%; (RP-HPLC) ≥99.0%.
Impurity profile: (HPLC) any single critical impurity ≤ 0.15%; total critical impurities ≤ 0.3%; total impurities ≤ 1.0%.
Assay: (HPLC) 98.0%~102.0%.
Sulfate ash: (muffle furnace) ≤0.1%.
Residual solven: (GC) ≤1.5%.
Moisture content: (Karl Fischer) ≤0.2%
Clarity of solution: (visual inspection) the solution shall be clear and free of insoluble substances.
Storage: -20±5℃.
2-Meo-Phosphoramidites:
2'-OMe-Bz-A-CE-Phosphoramidite (CAS No.: 110782-31-5)
2'-OMe-iBu-G-CE-Phosphoramidite (CAS No.: 150780-67-9)
2'-OMe-Bz-C-CE-Phosphoramidite (CAS No.: 110764-78-8)
2'-OMe-U-CE-Phosphoramidite(CAS No.: 110764-79-9)
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