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Home > Antibodies > Anti-Human Antibodies (In Vivo) > Anti-Human CD19 Monoclonal Antibodies (Clone: B43)

Anti-Human CD19 Monoclonal Antibodies (Clone: B43)

B-lymphocyte antigen CD19, Cluster of Differentiation 19, B-Lymphocyte Surface Antigen B4, T-Cell Surface Antigen Leu-12, CVID3

Catalog No. Product Name Size List Price (US$) Quantity
PA007272.m2a In vivo Grade Recombinant Anti-human CD19 Monoclonal Antibody (Clone: B43), Mouse IgG2a Kappa 1 mg 150.00
PA007272.m2a In vivo Grade Recombinant Anti-human CD19 Monoclonal Antibody (Clone: B43), Mouse IgG2a Kappa 5 mg 350.00
PA007272.m2a In vivo Grade Recombinant Anti-human CD19 Monoclonal Antibody (Clone: B43), Mouse IgG2a Kappa 25 mg 900.00
PA007272.h1Fs In vivo Grade Recombinant Anti-human CD19 Monoclonal Antibody (Clone: B43), Human IgG1 Fc Silent Kappa 1 mg 150.00
PA007272.h1Fs In vivo Grade Recombinant Anti-human CD19 Monoclonal Antibody (Clone: B43), Human IgG1 Fc Silent Kappa 5 mg 350.00
PA007272.h1Fs In vivo Grade Recombinant Anti-human CD19 Monoclonal Antibody (Clone: B43), Human IgG1 Fc Silent Kappa 25 mg 900.00
Description

PA007272.m2a: In vivo Grade Recombinant Anti-human CD19 Monoclonal Antibody, Mouse IgG2a Kappa (Clone: B43)

Recombinant mouse IgG2a Monoclonal Antibody. 
Clone: B43.
Isotype: Mouse IgG2a kappa.
Source: The anti-human CD19 monoclonal antibody (clone: B43) was produced in mammalian cells.
Specificity/Sensitivity: The in vivo grade recombinant mouse monoclonal antibody (clone: B43) specifically binds to the human CD19 protein.
Applications: ELISA, flow cytometry, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the human CD19 protein. 
Form of Antibody: 0.2 uM filtered solution, pH 7.4, no stabilizers or preservatives.
Endotoxin: < 1 EU per 1 mg of the protein by the LAL method.
Purity: >95% by SDS-PAGE under reducing conditions and HPLC.

PA007272.h1Fs: In vivo Grade Recombinant Anti-human CD19 Monoclonal Antibody, Human IgG1 Fc Silent Kappa (Clone: B43)

Recombinant human IgG1 monoclonal antibody with Fc silent mutation.
Clone: B43.
Isotype: Human IgG1 kappa.
Source: The anti-human CD19 monoclonal antibody (clone: B43) was produced in mammalian cells.
Specificity/Sensitivity: The in vivo grade recombinant mouse monoclonal antibody (clone: B43) specifically binds to the human CD19 protein.
Applications: ELISA, flow cytometry, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the human CD19 protein. 
Form of Antibody: 0.2 uM filtered solution, pH 7.4, no stabilizers or preservatives.
Endotoxin: < 1 EU per 1 mg of the protein by the LAL method.
Purity: >95% by SDS-PAGE under reducing conditions and HPLC.

Shipping: The antibody is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70°C as supplied.
1 month from date of receipt, 2 to 8°C as supplied.

Background

The B43 antibody binds to the human CD19 protein, a transmembrane protein expressed in all B lineage cells including human plasma cells. CD19 plays two major roles in human B cells: it acts as an adaptor protein to recruit cytoplasmic signaling proteins to the membrane, and works within the CD19/CD21 complex to decrease the threshold for B cell receptor signaling pathways. CD19 is a biomarker for B lymphocyte development, lymphoma diagnosis and can be utilized as a target for leukemia immunotherapies.

Syd Labs also provides the following in vivo grade recombinant anti-human CD19 antibodies:
Anti-human CD19 monoclonal antibody (Clone: B43)
Anti-human CD19 monoclonal antibody (Clone: SJ25C1)
Anti-human CD19 monoclonal antibody (Clone: FMC63)

Syd Labs provides the following in vivo grade recombinant anti-mouse CD19 antibodies:
Anti-mouse CD19 monoclonal antibody (Clone: 1D3)

Syd Labs provides the following recombinant anti-human CD19 antibodies for flow cytometry:
Anti-human CD19 monoclonal antibody (Clone: SJ25C1) for flow cytometry

Syd Labs provides the following recombinant anti-mouse CD19 antibodies for flow cytometry:
Anti-mouse CD19 monoclonal antibody (Clone: 1D3) for flow cytometry

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