To produce hapten-carrier conjugates for immunization of laboratory animals.
- IA000025-1007
Divinyl Sulfone (DVS) Activated Beads are rigid Sepharose beads loaded with high density of reactive groups. The matrix is suitable for binding amino, or hydroxyl groups, Present on biomolecules such as proteins and carbohydrates. The DVS activated beads are stable for extended period of time when stored refrigerated and light-protected. Coupling reactions to biomolecules may be done between pH values of 8-10 pH. - IA000024-1002
Divinyl Sulfone - A (DVS-A) Activated Beads are rigid Sepharose beads loaded with high density of reactive groups. The matrix is optimized for binding thiol groups, Present on biomolecules such as proteins and peptides. The DVS-A activated beads are stable for extended period of time when stored refrigerated and light-protected. Coupling reactions to biomolecules may be done between pH values of 6-8 pH. - IA000023-1015
Ig-Thio-Capture Beads absorbent is a chemical based immunoadsorbent aimed for the purification of immunoglobulins. Ig-Thio-Capture Beads support is based on the ability of some proteins, especially immunoglobulins, to bind to an immobilized chemical ligand that contains a sulfone group in close proximity to a thioether. The Ig-Thio-Capture Beads also termed thiophilic adsorption chromatography provides a low cost,efficient alternative to other antibody purification methods. The purification withthiophilic gel is a simple, rapid, one step purification method for antibody purification from serum, ascites or tissue culture supernatant. In addition, the method exhibits good protein recovery with excellent preservation of antibody activity due to gentle elution conditions, which usually yield concentrated, essentially salt-free, highly purified immunoglobulins at near neutral pH. The gel has a high binding capacity and it has a broad specificity toward immunoglobulins derived from various animal species irrespective of the type of immunoglobulin or the immunoglobulin subclass. - IA000022-1017: Protein G Beads
Protein G originated from Streptococci is a monomeric protein with a molecular weight of about 50,000 kDa. Protein G binds with high affinity to the Fc region of most classes and subclasses of immunoglobulins from Mouse, Rabbit, Goat and Human. Due to this binding ability, Protein G is commonly used in the purification and recovery of either polyclonal or monoclonal immunoglobulins. Recombinant Protein-G used in Syd Labs's Protein G beads is a genetically engineered form of Protein-G. Non-essential regions have been removed while leaving the IgG binding sites intact. The recombinant Protein G has been immobilized on Sepharose beads in order to create a versatile product for both the purification of various mammalian immunoglobulins and for isolating immune complexes by immunoprecipitation (IP). - IA000020-1042: Protein G
Recombinant Protein-G used in Protein G beads is a genetically engineered form of Protein-G. Non-essential regions have been removed while leaving the IgG binding sites intact.
Protein G has been extensively used for the isolation of IgG from several species of mammals. Although binding of Protein G to IgG's is not equivalent for all IgG subclasses, Protein-G possesses properties that have made it a popular choice for antibodies isolation. Protein G binds immunoglobulins at the Fc region of leaving the Fab region free to bind the antigen. Hence, Protein G is extremely useful for isolating of immune complexes. - IA000027-5007
It is a proprietary adjuvant mixture, formulated for the immunization of laboratory animals such as Mice and Rabbits. Composition is guaranteed to minimize stress to the animals by minimizing inflammatory responses, while maintaining excellent humeral immune response to antigen, resulting with the induction of high affinity and high titer antibodies. - IA000028-5009
Platinum Adjuvant is a proprietary adjuvant mixture, formulated for the immunization of laboratory animals such as Mice and Rabbits. Composition is guaranteed to minimize stress to the animals by minimizing inflammatory responses, while maintaining excellent humeral immune response to antigen, resulting with the induction of high affinity and high titer antibodies. - IA000029-1025
Activated KLH and BSA are commonly used as protein carriers for haptens such as peptides in order to enable the immune response to small molecules. In many cases KLH conjugate is used for the immunization, while BSA conjugate is used in immunoassys of the resulting antibodies. BSA conjugates are used in order to filter out the antibodies directed to the KLH. However in some cases BSA or other proteins are prefered as carrier proteins because of a variety of other reasons. The Maleimide activated KLH and BSA are preactivated with a heterobifunctional cross-linker (GMBS). These activated proteins may be reacted with biomolecules that contain a free sulfhydryl groups, to form a stable thioether bond. - IA000030-1026
Activated KLH, BSA and Ovalbumin (OVA), are commonly used as protein carriers for haptens such as peptides in order to enable the immune response to small molecules. In many cases KLH conjugate is used for the immunization, while
BSA or OVA conjugate is used in immunoassys of the resulting antibodies. OVA conjugates are used in order to filter out the antibodies directed to the KLH. However in some cases OVA or other proteins are preffered as carrier proteins because of a variety of other reasons. The Maleimide activated KLH and OVA are preactivated with a heterobifunctional cross-linker (GMBS). These activated proteins may be reacted with biomolecules that contain a free sulfhydryl groups, to form a stable thioether bond. - IA000031-1027
Activated KLH and BSA are commonly used as protein carriers for haptens such as peptides, in order to enable the immune response to these small molecules. KLH is most popular for immunization while BSA conjugate is used in immunoassays of the resulting antibodies in order to filter out the anti KLH response.
The Maleimide activated KLH and BSA are preactivated with a heterobifunctional cross-linker (GMBS). These activated proteins can be reacted with compounds that contain a free sulfhydryl group to form a stable thioether bond.
80 Activated Carrier Proteins Products