PA007156.m2c: In vivo Grade Recombinant Anti-mouse CD25 Monoclonal Antibody (Clone PC61.5.3), Mouse IgG2c Kappa
The in vivo grade recombinant anti-mouse CD25 mouse IgG2c monoclonal antibody was produced in CHO cells.
Applications: immunoprecipitation (IP), immunohistochemistry (IHC), Flow Cytometry (FC), and various functional assays, such as in vivo depletion of CD25+CD4+ Treg cells, in vitro blocking of IL-2 binding to low- and high-affinity receptors, and growth inhibition of IL-2-dependent T-cell lines.
Endotoxin Level: Less than 1 EU/mg of protein as determined by LAL method.PA007156.m2caf: In vivo Grade Recombinant Afucosylated Anti-mouse CD25 Monoclonal Antibody (Clone PC61.5.3), Mouse IgG2c Kappa
The in vivo grade recombinant afucosylated anti-mouse CD25 mouse IgG2c monoclonal antibody was produced in engineered CHO cells which produce afucosylated antibodies.
Applications: immunoprecipitation (IP), immunohistochemistry (IHC), Flow Cytometry (FC), and various functional assays, such as in vivo depletion of CD25+CD4+ Treg cells, in vitro blocking of IL-2 binding to low- and high-affinity receptors, and growth inhibition of IL-2-dependent T-cell lines.
Endotoxin Level: Less than 1 EU/mg of protein as determined by LAL method.BP000227-CYT-633: Recombinant Human Osteoprotegerin, Hi-5
Source: Hi-5-derived.
A single, glycosylated polypeptide chain containing 398 amino acid residues (22-401 a.a.), having a calculated molecular mass of 45.6 kDa.
Purity > 85%, by SDS-PAGE.BP000051-GD14: Recombinant Human OPG-Fc Fusion Protein
Source: HEK 293-derived.
The Osteoprotegerin / OPG / TNFRSF11B / OCIF / OBF activity is calculated by its ability to inhibit TRAIL-mediated cytotoxicity using L929 mouse fibrosarcoma cells treated with TRAIL. The ED50 for this effect is typically 5 ng/ml.
Endotoxin: < 5.0 EU per 1 ug of the protein by the LAL method.
Purity: > 90% by SDS-PAGE and RP-HPLC.BP003625: Cynomolgus TRAIL R2/DR5/TNFRSF10B Protein with the C-His Tag
Source: The recombinant Cynomolgus TRAIL R2/DR5/TNFRSF10B Protein, (amino acids Ile58-Ser212) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Cynomolgus TRAIL R2 protein with the C-His tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Anti-TRAIL R2 Antibody protein with the C-hFc tag with the EC50 of 3.9 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.BP000129-C326: Recombinant Human Tumor Necrosis Factor Ligand Superfamily Member 10 (TNFSF10) Protein
Source: HEK 293-derived.
Purity: > 95% by reducing SDS-PAGE and SEC-HPLC.
Endotoxin: < 0.1 ng/ug (1 IEU/ug).C044P: Drozitumab Biosimilar, TRAIL Monoclonal Antibody
Recombinant Humanized IgG1 Monoclonal Antibody.
Specificity/Sensitivity: The in vivo grade drozitumab biosimilar specifically binds to death receptor DR5 and induces apoptosis.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by drozitumab.EK000114-EK0532: Human TRAIL ELISA Kit
Range 15.6ug/ml-1000ug/ml
Sensitivity < 1ug/ml
Specificity: No detectable cross-reactivity with any other cytokine.
Application: For quantitative detection of human TRAIL in sera, plasma, body fluids, tissue lysates or cell culture supernates.
Expiration: four months at 4°C and eight months at -20°C.BP004602: Mouse TRAIL R2/DR5/TNFRSF10B Protein with the C-His Tag
Source: The recombinant Mouse TRAIL R2/DR5/TNFRSF10B Protein, (amino acids Asn53-Lys180) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Activity: The affinity constant of 0.43 nM as determined in SPR assay (Biacore T200).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.PA005342-PA1419: TRAIL Polyclonal Antibody
Rabbit Polyclonal Antibody;
Applications: WB, IHC-P;
Reactivity: Mouse, Rat;
Isotype: Rabbit IgG.BP001640-C504: Recombinant Human Tumor Necrosis Factor Receptor Superfamily Member 10C (TNFRSF10C) Protein
Source: HEK 293-derived.
Purity: > 95% by SEC-HPLC and reducing SDS-PAGE.
Endotoxin: < 0.1 ng/ug (1 IEU/ug).