PA007156.m2c: In vivo Grade Recombinant Anti-mouse CD25 Monoclonal Antibody (Clone PC61.5.3), Mouse IgG2c Kappa
The in vivo grade recombinant anti-mouse CD25 mouse IgG2c monoclonal antibody was produced in CHO cells.
Applications: immunoprecipitation (IP), immunohistochemistry (IHC), Flow Cytometry (FC), and various functional assays, such as in vivo depletion of CD25+CD4+ Treg cells, in vitro blocking of IL-2 binding to low- and high-affinity receptors, and growth inhibition of IL-2-dependent T-cell lines.
Endotoxin Level: Less than 1 EU/mg of protein as determined by LAL method.PA007156.m2caf: In vivo Grade Recombinant Afucosylated Anti-mouse CD25 Monoclonal Antibody (Clone PC61.5.3), Mouse IgG2c Kappa
The in vivo grade recombinant afucosylated anti-mouse CD25 mouse IgG2c monoclonal antibody was produced in engineered CHO cells which produce afucosylated antibodies.
Applications: immunoprecipitation (IP), immunohistochemistry (IHC), Flow Cytometry (FC), and various functional assays, such as in vivo depletion of CD25+CD4+ Treg cells, in vitro blocking of IL-2 binding to low- and high-affinity receptors, and growth inhibition of IL-2-dependent T-cell lines.
Endotoxin Level: Less than 1 EU/mg of protein as determined by LAL method.BP000227-CYT-633: Recombinant Human Osteoprotegerin, Hi-5
Source: Hi-5-derived.
A single, glycosylated polypeptide chain containing 398 amino acid residues (22-401 a.a.), having a calculated molecular mass of 45.6 kDa.
Purity > 85%, by SDS-PAGE.BP000051-GD14: Recombinant Human OPG-Fc Fusion Protein
Source: HEK 293-derived.
The Osteoprotegerin / OPG / TNFRSF11B / OCIF / OBF activity is calculated by its ability to inhibit TRAIL-mediated cytotoxicity using L929 mouse fibrosarcoma cells treated with TRAIL. The ED50 for this effect is typically 5 ng/ml.
Endotoxin: < 5.0 EU per 1 ug of the protein by the LAL method.
Purity: > 90% by SDS-PAGE and RP-HPLC.PA006350-PA1975: TNFRSF10A Polyclonal Antibody
Rabbit Polyclonal Antibody;
Applications: WB;
Reactivity: Human;
Isotype: Rabbit IgG.BP002458-CYT-069: Recombinant Human Tumor necrosis factor receptor superfamily member 10B (TNFRSF10B) Protein
Source: E. coli-derived.
The TNFRSF10B reduced the production of LPS-induced TNF by its ability to neutralize endogenous TRAIL in fresh human PBMC. In this assay, endogenous TRAIL is induced during a 24 hour exposure to LPS (10 ng/mL) but in the presence of TNFRSF10B, TRAIL-induced TNF is suppressed.
Purity: > 95.0% by SDS-PAGE.BP005719: Human TRAIL R4/TNFRSF10D Protein with the C-His-Avi Tag
Source: The recombinant Human TRAIL R4/TNFRSF10D Protein, (amino acids Ala56-His211) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human TRAIL protein with the C-His-Avi tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Human TRAIL R4 protein with the C-His tag with the EC50 of 0.13 ug/ml determined by ELISA (QC Test). The affinity constant of 0.13 nM as determined in SPR assay (Biacore T200).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.BP004305: Human TRAIL R2/DR5/TNFRSF10B Protein with the C-hFc Tag
Source: The recombinant Human TRAIL R2/DR5/TNFRSF10B Protein, (amino acids Ile56-Glu182) fused with a hFc tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human Trail protein with the C-hFc tag at 2 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Human TRAIL R2 protein with the C-hFc tag with the EC50 of 4.8 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.BP005541: Human TRAIL R2/DR5/TNFRSF10B Protein with the C-His-Avi Tag
Source: The recombinant Human TRAIL R2/DR5/TNFRSF10B Protein, (amino acids Ile56-Glu182) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human TRAIL R2 protein with the C-His-Avi tag at 0.5 ug/ml (100 ul/Well) on the plate. Dose response curve for the recombinant Anti-TRAIL R2 Antibody protein with the C-hFc tag with the EC50 of 8.5 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.BP000129-C022: Recombinant Human Tumor Necrosis Factor Ligand Superfamily Member 10 (TNFSF10) Protein
Source: E. coli-derived.
The ED50 as determined by the cytolysis of murine L929 cells in the presence of Actinomycin D is less than 2 ug/ml, corresponding to a Specific Activity of 5.0 x 106 IU/mg.
Purity: > 95% by RP-HPLC and reducing SDS-PAGE.
Endotoxin: < 0.1 ng/ug (1 IEU/ug).BP004662: Human DcR1/TRAILR3 Protein with the C-His Tag
Source: The recombinant Human DcR1/TRAILR3 Protein, (amino acids Tyr24-Ala236) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Activity: The affinity constant of 0.57 nM as determined in SPR assay (Biacore T200).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.BP000129-C326: Recombinant Human Tumor Necrosis Factor Ligand Superfamily Member 10 (TNFSF10) Protein
Source: HEK 293-derived.
Purity: > 95% by reducing SDS-PAGE and SEC-HPLC.
Endotoxin: < 0.1 ng/ug (1 IEU/ug).