BP004837: Biotinylated Cynomolgus TSLP Protein with the C-His Tag
Source: The recombinant Biotinylated Cynomolgus TSLP Protein, (amino acids Tyr29-Gln159) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Biotinylated Cynomolgus TSLP protein with the C-His tag at 0.5 ug/ml (100 ul/well) on the streptavidin precoated plate (5 ug/ml). Dose response curve for the recombinant Anti-TSLP Antibody protein with the C-hFc tag with the EC50 of 11.2 ng/ml determined by ELISA (QC Test).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.BP005728: Biotinylated Human TSLP (R127A, R130A) Protein with the C-His-Avi Tag
Source: The recombinant Biotinylated Human TSLP (R127A, R130A) Protein, (amino acids Tyr29-Gln159(R127A,R130A)) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Biotinylated Human TSLP (R127A, R130A) protein with the C-His-Avi tag at 1 ug/ml (100 ul/well) on the streptavidin precoated plate (5 ug/ml). Dose response curve for the recombinant Human TSLPR protein with the C-hFc tag with the EC50 of 3.0 ng/ml determined by ELISA (QC Test).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.BP005682: Biotinylated Human TSLP Protein with the C-His-Avi Tag
Source: The recombinant Biotinylated Human TSLP Protein, (amino acids Tyr29-Gln159) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Anti-TSLP Antibody protein with the C-His-Avi tag at 0.5 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Biotinylated Human TSLP protein with the C-His tag with the EC50 of 1.6 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.BP004958: Cynomolgus TSLP Protein with the C-His Tag
Source: The recombinant Cynomolgus TSLP Protein, (amino acids Tyr29-Gln159) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Cynomolgus TSLP protein with the C-His tag at 1 ug/ml (100 ul/Well) on the plate. Dose response curve for the recombinant Anti-TSLP Antibody protein with the C-hFc tag with the EC50 of 13.6 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.BP005431: Human TSLP (R127A, R130A) Protein with the C-His-Avi Tag
Source: The recombinant Human TSLP (R127A, R130A) Protein, (amino acids Tyr29-Gln159(R127A,R130A)) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human TSLP (R127A, R130A) protein with the C-His-Avi tag at 2 ug/ml (100 ul/Well). Dose response curve for the recombinant Human TSLPR protein with the C-hFc tag with the EC50 of 4.0 ng/ml determined by ELISA (QC Test).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.BP003443: Human TSLP Protein with the C-hFc Tag
Source: The recombinant Human TSLP Protein, (amino acids Tyr29-Gln159) fused with a hFc tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human TSLP protein with the C-hFc tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Human TSLPR protein with the C-His tag with the EC50 of 1.33 ug/ml determined by ELISA (QC Test).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.
BP005430: Human TSLP Protein with the C-His-Avi Tag
Source: The recombinant Human TSLP Protein, (amino acids Tyr29-Gln159) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human TSLP protein with the C-His-Avi tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Human TSLPR protein with the C-hFc tag with the EC50 of 50.8 ng/ml determined by ELISA (QC Test). The affinity constant of 9.21 nM as determined in SPR assay (Biacore T200).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.C120P: Tezepelumab Biosimilar, Human TSLP Monoclonal Antibody
Recombinant Humanized IgG2 lambda Monoclonal Antibody.
Specificity/Sensitivity: The in vivo grade tezepelumab biosimilar specifically binds to the TSLP protein.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by tezepelumab.BP000107-CYT-572: Recombinant Human Thymic Stromal Lymphopoietin (TSLP)
Source: E. coli-derived.
A single, non-glycosylated polypeptide chain containing 132 amino acids and having a molecular mass of 15 kDa.
The ED50 is determined by the ability to induce proliferation of human Interleukin-7 receptor alpha & human TSLP Receptor co-transfected with mouse BaF3 cells which was found to be less than 0.3 ug/ml.
Purity > 97%, by SDS-PAGE and RP-HPLC.