PA007584.m2c: In Vivo Grade Recombinant Anti-mouse MHC Class II (I-Ak, I-Ar, I-Af, I-As, I-Ag7) Monoclonal Antibody (Clone: 10-3.6.2), Mouse IgG2c Kappa
Recombinant Mouse IgG2c Monoclonal Antibody.
Specificity/Sensitivity: The in vivo grade recombinant mouse monoclonal antibody (clone: 10-3.6.2) specifically binds to mouse MHC Class II (I-Ak, I-Ar, I-Af, I-As, I-Ag7).
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the mouse MHC Class II (I-Ak, I-Ar, I-Af, I-As, I-Ag7) protein.PA007580.r2a: In Vivo Grade Recombinant Anti-mouse CD45RB Monoclonal Antibody (Clone: MB23G2), Rat IgG2a Kappa
Recombinant Rat IgG2a Monoclonal Antibody.
Specificity/Sensitivity: The in vivo grade recombinant rat monoclonal antibody (clone: MB23G2) specifically binds to mouse CD45RB.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the mouse CD45RB protein.PA007143: In Vivo Grade Recombinant Rat IgG2a Isotype Control Antibody
The in vivo grade recombinant rat IgG2a isotype control antibody was produced in mammalian cells.
Applications: an isotype-matched negative control for rat IgG2a kappa antibodies used in ELISA, Western Blot (WB), Flow Cytometry (Flow), Immunoprecipitation (IP), Immunohistochemistry (Paraffin) (IHC (P)), Immunohistochemistry (Frozen) (IHC (F)), and in vivo animal model research.
Endotoxin: Less than 1 EU/mg of protein as determined by LAL method.Experienced scientists working on antigen and antibody production, antibody engineering, lentivirus, and cell line development services for decades. >90% success rate of stable cell line generation.
Fast turnaround:
Antigen (peptide or protein) production: 3-6 weeks.
Mouse monoclonal antibody production: 20-24 weeks.
Screening phage or yeast libraries for fully human antibodies: 8-12 weeks.
Sequencing hybrioma antibody: 1-3 weeks.
Chimeric antibody production: 3-4 weeks.
Antibody humanization: 8-10 weeks.
Construction of CAR cassette, lentivirus packaging and production: 4-5 weeks.
T-cell activation, transduction, and CAR T-cell expansion: 4-5 weeks.
Confirmation of CAR expression, IFN-gamma ELISA, and cytotoxicity assay of transduced and expanded T-cells: 2 weeks.BP000324-CYT-304: Recombinant Human Soluble CD4
Source: Baculovirus-derived.
Immune reactive in ELISA using monoclonal anti CD4 in gpl2O capture ELISA assays.
Purity > 90%, by SDS-PAGE and RP-HPLC.BP005146: Cynomolgus/Rhesus macaque 4-1BB/TNFRSF9 Protein with the C-His Tag
Source: The recombinant Cynomolgus/Rhesus macaque 4-1BB/TNFRSF9 Protein, (amino acids Leu24-Gln186) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Cynomolgus/Rhesus macaque 4-1BB protein with the C-His tag at 0.2 ug/ml (100 ul/Well) on the plate. Dose response curve for the recombinant Cynomolgus 4-1BB Ligand protein with the C-hFc tag with the EC50 of 3.3 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.BP000325-CYT-472: Recombinant Mouse Soluble CD-40 Ligand/TRAP
Source: E. coli-derived.
A non-glycosylated, Polypeptide chain containing 149 amino acids and having a molecular mass of 16409 Dalton.
The ED50 as determined by its ability to induce MIP-1 alpha & TNF-alpha from mouse splenocytes was found to be 0.1 ?/ml corresponding to a Specific Activity of 10 MIU/mg.
Purity > 98%, by SDS-PAGE and RP-HPLC.BP005297: Human 4-1BB/TNFRSF9 Protein with the C-His Tag
Source: The recombinant Human 4-1BB/TNFRSF9 Protein, (amino acids Leu24-Gln186) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human 4-1BB protein with the C-His tag at 1 ug/ml (100 ul/Well) on the plate. Dose response curve for the recombinant Human 4-1BB Ligand Trimer protein with the C-hFc tag with the EC50 of 3.3 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.BP000325-CYT-670: Recombinant Human soluble CD40 Ligand/TRAP, His Tag
Source: E. coli-derived.
A single, non-glycosylated, polypeptide chain containing 169 amino acids (113-261 a.a.) and having a molecular mass of 18.3 kDa.
Purity > 95%, by SDS-PAGE.BP005472: Biotinylated Human 4-1BB/TNFRSF9 Protein with the C-His-Avi Tag
Source: The recombinant Biotinylated Human 4-1BB/TNFRSF9 Protein, (amino acids Leu24-Gln186) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human 4-1BB Ligand (Trimer) protein with the C-His-Avi tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Biotinylated Human 4-1BB protein with the C-His tag with the EC50 of 0.16 ug/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.