C119P: Sarilumab Biosimilar, Human IL-6R Monoclonal Antibody
Recombinant Humanized IgG1 kappa Monoclonal Antibody.
Specificity/Sensitivity: The in vivo grade mepolizumab biosimilar specifically binds to the IL-6R protein.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by sarilumab.BP000172-CYT-286: Recombinant Human IL-6 Soluble Receptor
Source: E. coli-derived.
A single, non-glycosylated polypeptide chain containing 338 amino acids (20-357) corresponding to the mature IL-6R protein, having a molecular weight of 42.25 kDa, with an aminoterminal hexahistidine tag.
Purity > 90%, by SDS-PAGE and RP-HPLC.