PA008041.m2cLA: In Vivo Grade Recombinant Anti-mouse/human PD-L1 / VEGFR-2 Bispecific Antibody, Mouse IgG2c LALAPG Kappa (Clone Ate / DC101)

The in vivo grade recombinant anti-mouse/human PD-L1 / VEGFR-2 bispecific antibody (mouse IgG2c LALAPG Kappa) was produced in mammalian cells.
Applications: immunohistochemistry (IHC), Flow Cytometry (FC), and various in vitro and in vivo functional assays.
Endotoxin Level: Less than 1 EU/mg of protein as determined by LAL method.

PA008040.m2cLA: In Vivo Grade Recombinant Anti-mouse/human PD-L1 / VEGF-A Bispecific Antibody, Mouse IgG2c LALAPG Kappa (Clone Ate / G6-31)

The in vivo grade recombinant anti-mouse/human PD-L1 / VEGF-A bispecific antibody (mouse IgG2c LALAPG Kappa) was produced in mammalian cells.
Applications: immunohistochemistry (IHC), Flow Cytometry (FC), and various in vitro and in vivo functional assays.
Endotoxin Level: Less than 1 EU/mg of protein as determined by LAL method.

PA008038.m2cLA: In Vivo Grade Recombinant Anti-mouse/human PD-L1 / VEGF-A Bispecific Antibody, Mouse IgG2c LALAPG Kappa (Clone Ate / B20-4.1.1.1)

The in vivo grade recombinant anti-mouse/human PD-L1 / VEGF-A bispecific antibody (mouse IgG2c LALAPG Kappa) was produced in mammalian cells.
Applications: immunohistochemistry (IHC), Flow Cytometry (FC), and various in vitro and in vivo functional assays.
Endotoxin Level: Less than 1 EU/mg of protein as determined by LAL method.

PA008039.m2cLA: In Vivo Grade Recombinant Anti-mouse/human PD-L1 / VEGF-A Bispecific Antibody, Mouse IgG2c LALAPG Kappa (Clone Ate / G6-23)

The in vivo grade recombinant anti-mouse/human PD-L1 / VEGF-A bispecific antibody (mouse IgG2c LALAPG Kappa) was produced in mammalian cells.
Applications: immunohistochemistry (IHC), Flow Cytometry (FC), and various in vitro and in vivo functional assays.
Endotoxin Level: Less than 1 EU/mg of protein as determined by LAL method.

PA007500.r2b: Recombinant Anti-mouse CD8b Monoclonal Antibody (Clone: YTS 156.7), Rat IgG2b Kappa

Recombinant Rat IgG2b Monoclonal Antibody.
Conjugation: Non-conjugated.
Specificity/Sensitivity: The recombinant YTS 156.7 antibody specifically binds to mouse CD8b protein.
Applications: Flow cytometry (FC), and Immunohistochemistry - Frozen (IHC-F).

PA007500.h1Fs: Recombinant Anti-mouse CD8b Monoclonal Antibody (Clone: YTS 156.7), Human IgG1 Fc Silent Kappa

Recombinant human IgG1 Monoclonal Antibody with Fc silent mutation.
Conjugation: Non-conjugated.
Specificity/Sensitivity: The recombinant YTS 156.7 antibody specifically binds to mouse CD8b protein.
Applications: Flow cytometry (FC), and Immunohistochemistry - Frozen (IHC-F).

PA007729.h1Fs-b: Biotinylated Recombinant Anti-mouse CD8b Monoclonal Antibody (Clone: YTS 156.7), Human IgG1 Fc Silent Kappa

Recombinant human IgG1 monoclonal antibody with site-directed biotinylation through the Avi tag at the C-terminus of the antibody heavy chain.
Conjugation: Biotin-conjugated.
Specificity/Sensitivity: The site-directed biotinylated recombinant YTS 156.7 antibody specifically binds to mouse CD8b protein.
Applications: Flow cytometry (FC) with various dye conjugation through streptavidin; conjugation to streptavidin agarose beads or streptavidin magnetic beads.

PA007545.m2a: In Vivo Grade Recombinant Anti-mouse CTLA-4 (CD152) Monoclonal Antibody (Clone: UC10-4F10-11), Mouse IgG2a Kappa

Recombinant mouse IgG2a Monoclonal Antibody.
Specificity/Sensitivity: The in vivo grade recombinant mouse monoclonal antibody (clone: UC10-4F10-11) specifically binds to mouse CTLA-4 (CD152).
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the mouse CTLA-4 (CD152) protein.

PA007545.hs: In Vivo Grade Recombinant Anti-mouse CTLA-4 (CD152) Monoclonal Antibody (Clone: UC10-4F10-11), Armenian hamster IgG

Recombinant hamster IgG Monoclonal Antibody.
Specificity/Sensitivity: The in vivo grade recombinant mouse monoclonal antibody (clone: UC10-4F10-11) specifically binds to mouse CTLA-4 (CD152).
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the mouse CTLA-4 (CD152) protein.

BP004987: Biotinylated Human PD-1/PDCD1 Protein with the C-His-Avi Tag

Source: The recombinant Biotinylated Human PD-1/PDCD1 Protein, (amino acids Leu25-Gln167) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Biotinylated Human PD-1 protein with the C-His-Avi tag at 1 ug/ml (100 ul/Well) on streptavidin (5 ug/ml) precoated plate. Dose response curve for the recombinant Human PD-L1 protein with the C-hFc Tag with the EC50 of 23.5ng/ml determined by ELISA (QC Test). The affinity constant of 2.356 uM as determined in SPR assay (Biacore T200).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP005587: Biotinylated Human PD-1/PDCD1 Protein with the C-hFc-Avi Tag

Source: The recombinant Biotinylated Human PD-1/PDCD1 Protein, (amino acids Leu25-Gln167) fused with a hFc-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human PD-L1 protein with the C-hFc-Avi tag at 2 ug/ml (100 ul/Well). Dose response curve for the recombinant Biotinylated Human PD-1 protein with the C-hFc tag with the EC50 of 0.23 ug/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

BP003743: Biotinylated Mouse PD-1/PDCD1 Protein with the C-hFc Tag

Source: The recombinant Biotinylated Mouse PD-1/PDCD1 Protein, (amino acids Leu25-Gln167) fused with a hFc tag at the C-terminus, was produced in HEK 293 cells.
Activity: The affinity constant of 3.35 uM as determined in SPR assay (Biacore T200).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.

PA007146: In Vivo Grade Recombinant Armenian Hamster IgG1 Isotype Control Antibody

The in vivo grade recombinant hamster IgG1 isotype control antibody was produced in mammalian cells.
Applications: an isotype-matched negative control for hamster IgG1 kappa antibodies used in ELISA, Western Blot (WB), Flow Cytometry (Flow), Immunoprecipitation (IP), Immunohistochemistry (Paraffin) (IHC (P)), Immunohistochemistry (Frozen) (IHC (F)), and in vivo animal model research.
Endotoxin: Less than 1 EU/mg of protein as determined by LAL method.

PA007148: In Vivo Grade Recombinant Syrian Hamster IgG1 Isotype Control Antibody

The in vivo grade recombinant hamster IgG1 isotype control antibody was produced in mammalian cells.
Applications: an isotype-matched negative control for hamster IgG1 kappa antibodies used in ELISA, Western Blot (WB), Flow Cytometry (Flow), Immunoprecipitation (IP), Immunohistochemistry (Paraffin) (IHC (P)), Immunohistochemistry (Frozen) (IHC (F)), and in vivo animal model research.
Endotoxin: Less than 1 EU/mg of protein as determined by LAL method.

C035P: Spartalizumab Biosimilar, PD-1 Monoclonal Antibody

Recombinant Humanized IgG4 Monoclonal Antibody.
Specificity/Sensitivity: The in vivo grade spartalizumab biosimilar specifically binds to the programmed cell death protein 1 (PD-1), antagonizing its interaction with its known ligands PD-L1 and PD-L2.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by spartalizumab.