Our complete custom Adeno-associated Virus (AAV) production services include: 1) AAV plasmid vector construction; 2) AAV packaging; 3) AAV purification by iodixanol or column chromatography; 4) AAV titering by qPCR.
We have always optimized our AAV production systems, including AAV plasmid vector design and construction and low endotoxin plasmid preparation, host cells for AAV packaging, cell culture medium and AAV packaging process, small and large scale AAV purification process.
Fast turnaround: 2-3 weeks.We provide large selection of pre-made adenovirus and complete custom adenovirus production services from small crude scale to large purified scale, including: 1) construction of an adenovirus vector for expression or silencing of a gene; 2) generation of adenovirus; 3) amplification and purification of adenovirus.
Our adenovirus production team has constructed, packaged, amplified, and purified thousands of adenoviruses for worldwide clients in more than a decade. An optimized technology is used to simplify and accelerate adenoviral vector construction for researchers studying gene expression or gene silencing in mammalian systems.
Fast turnaround: 2-3 weeks.Our Ad5-RGD and Ad5/35 adenovirus production services include: 1) construction of an Ad5-RGD and Ad5/35 adenovirus vector for expression or silencing of a gene; 2) generation of Ad5-RGD and Ad5/35 adenovirus; 3) amplification and purification of Ad5-RGD and Ad5/35 adenovirus.
Our adenovirus production team has constructed, amplified, and purified thousands of adenoviruses for worldwide clients in more than a decade. An improved technology is used to simplify and accelerate construction of adenoviral vectors for researchers studying gene expression or gene silencing in mammalian systems.
Fast turnaround: 2 weeks.Our adenovirus production services for toxic genes include: 1) construction of an adenovirus vector for expression of a cytotoxic gene; 2) generation of adenoviruses carrying cytotoxic genes; 3) amplification and purification of adenoviruses carrying cytotoxic genes.
Our adenovirus production team has constructed, amplified, and purified thousands of adenoviruses for worldwide clients in more than a decade. An improved technology is used to simplify and accelerate construction of adenoviral vectors for researchers studying gene expression or gene silencing in mammalian systems.
Fast turnaround: 2 weeks.BP000861-ENZ-406: Recombinant Human AKR1C3 (Aldo-keto reductase family 1 member C3)
Source: E. coli-derived.
Specific activity: approximately < 0.1 units/mg.
Purity > 95%, by SDS-PAGE.PA007705.m1: Recombinant Anti-Digoxin Monoclonal Antibody (Clone: 26-10), Mouse IgG1 Kappaa
Recombinant mouse IgG1 Monoclonal Antibody.
Specificity/Sensitivity: The recombinant anti-Digoxin monoclonal antibody (clone: 26-10) specifically binds to Digoxin.
Applications: Western Blot (WB), ELISA, Immunohistochemistry (IHC).PA007420.m1: Non-conjugated Recombinant Anti-human CD64 Monoclonal Antibody (Clone: 22), Mouse IgG1 Kappa
Recombinant mouse IgG1 Monoclonal Antibody.
Conjugation: Non-conjugated.
Specificity/Sensitivity: The recombinant 22 antibody specifically binds to human CD64.
Applications: Flow cytometry (FC), and Immunohistochemistry - Frozen (IHC-F).PA007420.h1Fs: Non-conjugated Recombinant Anti-human CD64 Monoclonal Antibody (Clone: 22), Human IgG1 Fc Silent Kappa
Recombinant human IgG1 Monoclonal Antibody with Fc silent mutation.
Conjugation: Non-conjugated.
Specificity/Sensitivity: The recombinant 22 antibody specifically binds to human CD64.
Applications: Flow cytometry (FC), and Immunohistochemistry - Frozen (IHC-F).PA007569.r1: In Vivo Grade Recombinant Anti-mouse CD1d (CD1.1) Monoclonal Antibody (Clone: 20H2), Rat IgG1 Kappa
Recombinant rat IgG1 Monoclonal Antibody.
Specificity/Sensitivity: The in vivo grade recombinant rat monoclonal antibody (clone: 20H2) specifically binds to mouse CD1d (CD1.1) .
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the mouse CD1d (CD1.1) protein.PA007580.r2a: In Vivo Grade Recombinant Anti-mouse CD45RB Monoclonal Antibody (Clone: MB23G2), Rat IgG2a Kappa
Recombinant Rat IgG2a Monoclonal Antibody.
Specificity/Sensitivity: The in vivo grade recombinant rat monoclonal antibody (clone: MB23G2) specifically binds to mouse CD45RB.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the mouse CD45RB protein.Fast turnaround: 8-10 weeks in total. Our antibody humanization process involves significant computational analysis, and thus is quite efficient and requires much less trial time.
A human antibody database and a proprietary method are used for analysis and design of humanized antibodies.
Nine humanized antibodies (each combination of 3 designed heavy chains and 3 designed light chains) are constructed and produced for antigen binding confirmation and affinity measurement.