BP002109-PRO-589: Recombinant Mycobacterium Tuberculosis major secretory protein Antigen 85B (Ag85B)

Source: E. Coli-derived.
Purity: > 90.0% as determined by: Analysis by RP-HPLC and SDS-PAGE.

PA007617.m1:In Vivo Grade Recombinant Anti-human CA19-9 Monoclonal Antibody (Clone: 1116-NS-19-9), Mouse IgG1 Kappa

Recombinant Mouse IgG1 Monoclonal Antibody.
Specificity/Sensitivity: The in vivo grade recombinant mouse monoclonal antibody (clone: 1116-NS-19-9) specifically binds to human CA19-9.
Applications:ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the human CA19-9 protein.

PA007421.m1: Non-conjugated Recombinant Anti-human CD3 Monoclonal Antibody (Clone: SP34-2), Mouse IgG1 Lambda

Recombinant  mouse IgG1 Monoclonal Antibody. 
Conjugation: Non-conjugated.
Specificity/Sensitivity: The recombinant SP34-2 antibody specifically binds to the human T cell receptor CD3 in denatured form and in native form.
Applications: Flow cytometry (FC), and Immunohistochemistry - Frozen (IHC-F). 

PA007421.h1Fs: Non-conjugated Recombinant Anti-human CD3 Monoclonal Antibody (Clone: SP34-2), Human IgG1 Fc Silent Kappa

Recombinant  human IgG1 Monoclonal Antibody with Fc silent mutation. 
Conjugation: Non-conjugated.
Specificity/Sensitivity: The recombinant SP34-2 antibody specifically binds to the human T cell receptor CD3 in denatured form and in native form.
Applications: Flow cytometry (FC), and Immunohistochemistry - Frozen (IHC-F).

PA007751.h1Fs-b: Biotinylated Recombinant Anti-human CD3e Monoclonal Antibody (Clone: SP34-2), Human IgG1 Fc Silent Kappa

Recombinant  human IgG1 monoclonal antibody  with site-directed  biotinylation through the Avi tag at the C-terminus of the antibody heavy chain.
Conjugation: Biotin-conjugated.
Specificity/Sensitivity: The site-directed biotinylated recombinant SP34-2 antibody specifically binds to the human, cynomolgus and rhesus T cell receptor CD3 epsilon subunit in denatured form and in native form.
Applications: Flow cytometry (FC) with various dye conjugation through streptavidin; conjugation to streptavidin agarose beads or streptavidin magnetic beads.

PA007711.m1: In Vivo Grade Recombinant Anti-mouse 2C TCR Monoclonal Antibody (Clone: 1B2), Mouse IgG1 Kappa

Recombinant mouse IgG1 monoclonal antibody.
Specificity/Sensitivity: The in vivo grade recombinant mouse monoclonal antibody (clone: 1B2) specifically binds to mouse 2C TCR .
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the mouse 2C TCR  protein.

PA007201: In vivo Grade Recombinant Anti-mouse CD3e Mouse IgG2a Kappa Monoclonal Antibody (Clone: 500A2)

Recombinant mouse IgG2a Monoclonal Antibody.
Specificity/Sensitivity: The in vivo grade recombinant mouse monoclonal antibody (clone: 500A2) specifically binds to the mouse T cell receptor CD3e.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the mouse CD3e protein.

PA007591.m2a: In Vivo Grade Recombinant Anti-mouse MHC Class I (H-2Db) Monoclonal Antibody (Clone: 28-14-8S), Mouse IgG2a Kappa

Recombinant Mouse IgG2a Monoclonal Antibody.
Specificity/Sensitivity: The in vivo grade recombinant mouse monoclonal antibody (clone: 28-14-8S) specifically binds to mouse MHC Class I (H-2Db).
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the mouse MHC Class I (H-2Db) protein.

PA007603.m: In Vivo Grade Recombinant Anti-mouse MHC Class II (Beta chain) Monoclonal Antibody (Clone: KL277), Mouse IgG

Recombinant Mouse IgG Monoclonal Antibody.
Specificity/Sensitivity: The in vivo grade recombinant mouse monoclonal antibody (clone: KL277) specifically binds to mouse MHC Class II (Beta chain).
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the mouse MHC Class II (Beta chain) protein.

PA007603.hs: In Vivo Grade Recombinant Anti-mouse MHC Class II (Beta chain) Monoclonal Antibody (Clone: KL277), Hamster IgG

Recombinant Hamster IgG Monoclonal Antibody.
Specificity/Sensitivity: The in vivo grade recombinant hamster monoclonal antibody (clone: KL277) specifically binds to mouse MHC Class II (Beta chain).
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the mouse MHC Class II (Beta chain) protein.

PA007523.m2a: Recombinant Anti-mouse TCRβ Monoclonal Antibody (Clone: H57-597), Mouse IgG2a Lambda

Recombinant mouse IgG2a Monoclonal Antibody.
Conjugation: non-conjugated.
Specificity/Sensitivity: The recombinant mouse monoclonal antibody (clone: H57-597) specifically binds to the mouse TCRβ.
Applications: Flow cytometry (FC), and Immunohistochemistry - Frozen (IHC-F).
 

PA007523.h1Fs: Recombinant Anti-mouse TCRβ Monoclonal Antibody (Clone: H57-597), Human IgG1 Fc Silent Kappa

Recombinant human IgG1 Monoclonal Antibody with Fc silent mutation.
Conjugation: non-conjugated.
Specificity/Sensitivity: The recombinant H57-597 antibody specifically binds to the mouse TCRβ.
Applications: Flow cytometry (FC), and Immunohistochemistry - Frozen (IHC-F).
 

PA007775.h1Fs-b: Biotinylated Recombinant Anti-mouse TCRβ Monoclonal Antibody (Clone: H57-597), Human IgG1 Fc Silent Kappa

Recombinant human IgG1 Monoclonal Antibody with site-directed biotinylation through the Avi tag at the C-terminus of the antibody heavy chain.
Conjugation: Biotin-conjugated.
Specificity/Sensitivity: The site-directed biotinylated recombinant H57-597 antibody specifically binds to the mouse TCRβ.
Applications: Flow cytometry (FC) with various dye conjugation through streptavidin; conjugation to streptavidin agarose beads or streptavidin magnetic beads.

PA007608.m2b: In Vivo Grade Recombinant Anti-swine MHC Class I (SLAd) Monoclonal Antibody (Clone: 74-11-10), Mouse IgG2b Kappa

Recombinant Mouse IgG2b Monoclonal Antibody.
Specificity/Sensitivity: The in vivo grade recombinant mouse monoclonal antibody (clone: 74-11-10) specifically binds to swine MHC Class I (SLAd).
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the swine MHC Class I (SLAd) protein.

Kinetic analysis is used to determine the affinity of an antibody to its soluble antigen using surface plasmon resonance (SPR) or biolayer interferometry (BLI), which can measure kon, koff, and kD. Association and dissociation are measured on the Biacore T100 or the ForteBio Octet QKe using various concentrations of the antigen and the kD is calculated using an appropriate curve-fitting model.

Fast turnaround time: 2-3 days per antibody-antigen pair, but may require more time depending on the complexity of analysis.