Biologics production stable cell line development services utilize advanced technology platforms to generate cell lines expressing the target gene at very high levels for the manufacturing of recombinant proteins and antibodies.
- Performed under GLP; manufactured product may be used in FDA Nonclinical Laboratory Studies.
- Parental cell line is cGMP banked with certification.
- Set licensing fee arrangement for commercial production license.
- Cell lineage history of the cell line and testing details facilitate IND filing.BP003397: Biotinylated Human HLA-A*02:01&B2M&PRAME (SLLQHLIGL) Monomer Protein with the C-His-Avi Tag
Source: The recombinant Biotinylated Human HLA-A*02:01&B2M&PRAME (SLLQHLIGL) Monomer Protein, (amino acids Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M)and SLLQHLIGL peptide) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity:
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.BP003508: Human HLA-A*02:01&B2M&PRAME (SLLQHLIGL) Tetramer Protein with the C-His-Avi Tag
Source: The recombinant Human HLA-A*02:01&B2M&PRAME (SLLQHLIGL) Tetramer Protein, (amino acids Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M)and SLLQHLIGL peptide) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human HLA-A*02:01&B2M&PRAME (SLLQHLIGL) Tetramer protein with the C-His-Avi tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant HLA-A*02:01&B2M&PRAME TCR with the EC50 of 9.5 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.BP003193: PE-Labeled Human HLA-A*02:01&B2M&PRAME (SLLQHLIGL) Tetramer Protein with the C-His-Avi Tag
Source: The recombinant PE-Labeled Human HLA-A*02:01&B2M&PRAME (SLLQHLIGL) Tetramer Protein, (amino acids Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M)and SLLQHLIGL peptide) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity:
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.BP003396: Human HLA-A*02:01&B2M&MAGE-A1 (KVLEYVIKV) Monomer Protein with the C-His-Avi Tag
Source: The recombinant Human HLA-A*02:01&B2M&MAGE-A1 (KVLEYVIKV) Monomer Protein, (amino acids Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and KVLEYVIKV peptide) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity: The affinity constant of 116.2 nM as determined in SPR assay (Biacore T200).
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.BP003395: Biotinylated Human HLA-A*02:01&B2M&MAGE-A1 (KVLEYVIKV) Monomer Protein with the C-His-Avi Tag
Source: The recombinant Biotinylated Human HLA-A*02:01&B2M&MAGE-A1 (KVLEYVIKV) Monomer Protein, (amino acids Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and KVLEYVIKV peptide) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity:
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.BP003394: Human HLA-A*02:01&B2M&MAGE-A1 (KVLEYVIKV) Tetramer Protein with the C-His-Avi Tag
Source: The recombinant Human HLA-A*02:01&B2M&MAGE-A1 (KVLEYVIKV) Tetramer Protein, (amino acids Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and KVLEYVIKV peptide) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity:
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.BP003142: PE-Labeled Human HLA-A*02:01&B2M&MAGE-A1 (KVLEYVIKV) Tetramer Protein with the C-His-Avi Tag
Source: The recombinant PE-Labeled Human HLA-A*02:01&B2M&MAGE-A1 (KVLEYVIKV) Tetramer Protein, (amino acids Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and KVLEYVIKV peptide) fused with a His-Avi tag at the C-terminus, was produced in HEK 293 cells.
Activity:
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.BP003636: Biotinylated Cynomolgus PSMA/FOLH1 Protein with the N-His Tag
Source: The recombinant Biotinylated Cynomolgus PSMA/FOLH1 Protein, (amino acids Lys44-Ala750) fused with a His tag at the N-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Anti-PSMA Antibody protein with the N-His tag at 0.5 ug/ml (100 ul/Well) on the plate. Dose response curve for the recombinant Biotinylated Cynomolgus PSMA protein with the N-His tag with the EC50 of 21.2 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.BP000339-GD15: Recombinant Human Chorionic Gonadotropin (hCG)
Source: CHO-derived.
The hCG α/β activity was determined to be 25,000 IU/mg.
Purity > 97% by SDS-PAGE under reducing conditions and visualized by silver stain, and 97% by SEC-HPLC.