C029P: Cemiplimab Biosimilar, PD-1 Monoclonal Antibody
Recombinant Humanized IgG4 Monoclonal Antibody.
Specificity/Sensitivity: The in vivo grade cemiplimab biosimilar specifically binds to the programmed cell death protein 1 (PD-1), antagonizing its interaction with its known ligands PD-L1 and PD-L2.
Applications: ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by cemiplimab.APIM050319: ARV-825
CAS No.: 1818885-28-7.
Purity: >99% by HPLC.
QC: HPLC-MS, NMR, and Quantitative Elemental Analysis.
Solubility: Soluble in DMSO.APIM050018: AZD5991
CAS No.: 2143061-81-6.
Purity: 99.8-100% Chemically and Atropisomerically Pure by achiral and chiral HPLCs.
QC: Achiral and Chiral HPLCs, MS, NMR, and Elemental Analysis, Binding Potency Reports.
Solubility: Refer to Certificate of Analysis.APIM050015: AZD4320
CAS No.: 1357576-48-7.
Purity: 99.9-100% by Achiral and Chiral HPLCs.
QC: Achiral and Chiral HPLCs, MS, 19F-, 1H-NMRs, and Quantitative Elemental Analysis Report.
Solubility: Refer to Certificate of Analysis.PA007173: In Vivo Grade Recombinant Anti-HIV CD4-Binding Site Human IgG1 Kappa Monoclonal Antibody
The in vivo grade recombinant anti-HIV CD4-binding site human IgG1 monoclonal antibody (clone of VRC07-523LS) was produced in mammalian cells.
Applications: ELISA, Western blot, immunohistochemistry (IHC), Flow Cytometry (FC), and various in vitro and in vivo functional assays.APIM050021: BCL-201 (S55746, Servier-1)
CAS No.: 1448525-91-4.
Purity: >99% Chemically and Enantiomerically Pure by achiral and chiral HPLCs.
QC: Achiral and Chiral HPLCs, MS, NMR, and Elemental Analysis.
Solubility: Refer to Certificate of Analysis.APIM050004: ABT-199 (VENETOCLAX)
Purity: 99.9% by HPLC at 214 and 254 nm.
QC: HPLC-MS, 1HNMR, and Quantitative Elemental Analysis Report.
Solubility: DMSO.APIM050295: BIRINAPANT
CAS No.: 1260251-31-7.
Purity: 99.5% by HPLC.
QC: HPLC-MS, 1HNMR, Chiral HPLC and Quantitative Elemental Analysis.
Solubility: Soluble in DMSO.APIM050293: AZD-0156 (AZD0156)
CAS No.: 1821428-35-6.
Purity: 99.9% (HPLC at 214 and 254 nm).
QC: HPLC, 1H-NMR, and Quantitative Elemental Analysis Report.
Solubility: Refer to Certificate of Analysis.BP002388-Z53: Recombinant Human Cellular tumor antigen p53 (p53) Protein
Source: Baculovirus, SF9 insect cells-derived.
Bioactivity test: 1 unit equals 1 nanogram of purified protein. 10 unit is sufficient for a gel mobility shift assay in a 20 ul reaction; 50 units are sufficient for reconstituted transcription assay and 100 units are sufficient for a protein-protein interaction assay.
Purity: > 95%, by SDS-PAGE.
Endotoxin Level: < 1.0 EU per 1 ug of the protein by the LAL method.