BP003373: Human/Murine/Rat BDNF Protein with No Tag
Source: The recombinant Human/Murine/Rat BDNF Protein, (amino acids His129-Arg247) fused with No tag at the terminus, was produced in E.coli cells.
Activity: Immobilized recombinant Human/Murine/Rat BDNF protein with No tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Human TrkB protein with the His tag with the EC50 of 0.17 ug/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.BP003426: Cynomolgus ROR2/NTRKR2 Protein with the C-His Tag
Source: The recombinant Cynomolgus ROR2/NTRKR2 Protein, (amino acids Glu34-Met402) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Cynomolgus ROR2 protein with the C-His tag at 0.5 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Anti-ROR2 Antibody protein with the C-hFc tag with the EC50 of 4.3 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.APIM050197: MGCD516 (SITRAVATINIB)
CAS No.: 1123837-84-2.
Purity: >98.5% by HPLC.
QC: HPLC-MS, 1HNMR, and Quantitative Elemental Analysis.
Solubility: Soluble in DMSO.APIM050039: LOXO-195 (SELITRECTINIB)
CAS No.: 2097002-61-2.
Purity: >99.5% chemical and optical purity by achiral and chiral HPLCs.
QC: Achiral and Chiral HPLCs, NMR, and Quantitative Elemental Analysis Report.
Solubility: Refer to Certificate of Analysis.APIM050139: DCC-2036 (REBASTINIB)
CAS No.: 1020172-07-9.
Purity: >99% (HPLC).
QC: 1HNMR, HPLC and MS.
Solubility: Soluble in DMSO.APIM050183: LOXO-101 (LAROTRECTINIB)
CAS No.: 1223403-58-4.
Purity: 99.9% chemical and stereomerical purity by achiral and chiral HPLCs.
QC: Achiral and Chiral HPLCs, 1H-NMR, and Elemental Analysis Report.
Solubility: Refer to certificate of analysis.APIM050184: LOXO-195 (SELITRECTINIB)
CAS No.: 2097002-61-2.
Purity: >99.5% chemical and optical purity by achiral and chiral HPLCs.
QC: Achiral and Chiral HPLCs, NMR, and Quantitative Elemental Analysis Report.
Solubility: Refer to Certificate of Analysis.BP004422: Human/Cynomolgus/Rhesus macaque ROR1 (39-151, Ig-like Domain) Protein with the C-His Tag
Source: The recombinant Human/Cynomolgus/Rhesus macaque ROR1 (39-151, Ig-like Domain) Protein, (amino acids Glu39-Gly151) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human/Cynomolgus/Rhesus macaque ROR1 (39-151, Ig-like Domain) protein with the C-His tag at 2 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Anti-ROR1 Antibody protein with the C-hFc tag with the EC50 of 3.0 ng/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.BP005046: Human TrkB/NTRK2 Protein with the C-His Tag
Source: The recombinant Human TrkB/NTRK2 Protein, (amino acids Cys32-His430) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Activity: Immobilized recombinant Human/Murine/Rat BDNF protein with the C-His tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for the recombinant Human TrkB protein with the C-His tag with the EC50 of 0.24 ug/ml determined by ELISA.
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.BP003276: Human TrkA Protein with the C-His Tag
Source: The recombinant Human TrkA Protein, (amino acids Ala33-Gly417) fused with a His tag at the C-terminus, was produced in HEK 293 cells.
Activity:
Purity: >95% by SEC-HPLC and SDS-PAGE under reducing conditions.
Endotoxin Level: Less than 1 EU per ug of protein as determined by LAL method.